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Open AccessFeature PaperReview

Recent Advances in Enzymatic and Chemoenzymatic Cascade Processes

1
Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, Cantoblanco, Campus UAM, 28049 Madrid, Spain
2
School of Biochemical Engineering, Pontificia Universidad Católica de Valparaíso, Avda. Brasil, 2085 Valparaíso, Chile
*
Author to whom correspondence should be addressed.
Catalysts 2020, 10(11), 1258; https://doi.org/10.3390/catal10111258
Received: 28 September 2020 / Revised: 27 October 2020 / Accepted: 28 October 2020 / Published: 30 October 2020
(This article belongs to the Special Issue Enzymes in Sustainable Chemistry)
Cascade reactions have been described as efficient and universal tools, and are of substantial interest in synthetic organic chemistry. This review article provides an overview of the novel and recent achievements in enzyme cascade processes catalyzed by multi-enzymatic or chemoenzymatic systems. The examples here selected collect the advances related to the application of the sequential use of enzymes in natural or genetically modified combination; second, the important combination of enzymes and metal complex systems, and finally we described the application of biocatalytic biohybrid systems on in situ catalytic solid-phase as a novel strategy. Examples of efficient and interesting enzymatic catalytic cascade processes in organic chemistry, in the production of important industrial products, such as the designing of novel biosensors or bio-chemocatalytic systems for medicinal chemistry application, are discussed View Full-Text
Keywords: enzymes; cascade catalysis; organometallic; biocatalysis; chemoenzymatic processes enzymes; cascade catalysis; organometallic; biocatalysis; chemoenzymatic processes
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MDPI and ACS Style

Losada-Garcia, N.; Cabrera, Z.; Urrutia, P.; Garcia-Sanz, C.; Andreu, A.; Palomo, J.M. Recent Advances in Enzymatic and Chemoenzymatic Cascade Processes. Catalysts 2020, 10, 1258. https://doi.org/10.3390/catal10111258

AMA Style

Losada-Garcia N, Cabrera Z, Urrutia P, Garcia-Sanz C, Andreu A, Palomo JM. Recent Advances in Enzymatic and Chemoenzymatic Cascade Processes. Catalysts. 2020; 10(11):1258. https://doi.org/10.3390/catal10111258

Chicago/Turabian Style

Losada-Garcia, Noelia; Cabrera, Zaida; Urrutia, Paulina; Garcia-Sanz, Carla; Andreu, Alicia; Palomo, Jose M. 2020. "Recent Advances in Enzymatic and Chemoenzymatic Cascade Processes" Catalysts 10, no. 11: 1258. https://doi.org/10.3390/catal10111258

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