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Review

A Systematic Review and Meta-Analysis Comparing Liver Resection with the Rf-Based Device Habib™-4X with the Clamp-Crush Technique

1
Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK
2
Department of General Surgery, University Hospital of Larissa, Mezourlo, 413 34 Larissa, Greece
3
Department of Surgery and Hepatitis Research Center, National Taiwan University Hospital, Taipei 100, Taiwan
*
Authors to whom correspondence should be addressed.
Cancers 2018, 10(11), 428; https://doi.org/10.3390/cancers10110428
Received: 28 September 2018 / Revised: 25 October 2018 / Accepted: 1 November 2018 / Published: 8 November 2018
Liver cancer is the sixth most common cancer and third most common cause of cancer-related mortality. Presently, indications for liver resections for liver cancers are widening, but the response is varied owing to the multitude of factors including excess intraoperative bleeding, increased blood transfusion requirement, post-hepatectomy liver failure and morbidity. The advent of the radiofrequency energy-based bipolar device Habib™-4X has made bloodless hepatic resection possible. The radiofrequency-generated coagulative necrosis on normal liver parenchyma provides a firm underpinning for the bloodless liver resection. This meta-analysis was undertaken to analyse the available data on the clinical effectiveness or outcomes of liver resection with Habib™-4X in comparison to the clamp-crush technique. The RF-assisted device Habib™-4X is considered a safe and feasible modality for liver resection compared to the clamp-crush technique owing to the multitude of benefits and mounting clinical evidence supporting its role as a superior liver resection device. The most intriguing advantage of the RF-device is its ability to induce systemic and local immunomodulatory changes that further expand the boundaries of survival outcomes following liver resection. View Full-Text
Keywords: liver cancer; liver resection; radiofrequency; Habib™-4X; clamp-crush technique liver cancer; liver resection; radiofrequency; Habib™-4X; clamp-crush technique
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MDPI and ACS Style

Jayant, K.; Sodergren, M.H.; Reccia, I.; Kusano, T.; Zacharoulis, D.; Spalding, D.; Pai, M.; Jiao, L.R.; Huang, K.W. A Systematic Review and Meta-Analysis Comparing Liver Resection with the Rf-Based Device Habib™-4X with the Clamp-Crush Technique. Cancers 2018, 10, 428. https://doi.org/10.3390/cancers10110428

AMA Style

Jayant K, Sodergren MH, Reccia I, Kusano T, Zacharoulis D, Spalding D, Pai M, Jiao LR, Huang KW. A Systematic Review and Meta-Analysis Comparing Liver Resection with the Rf-Based Device Habib™-4X with the Clamp-Crush Technique. Cancers. 2018; 10(11):428. https://doi.org/10.3390/cancers10110428

Chicago/Turabian Style

Jayant, Kumar, Mikael H. Sodergren, Isabella Reccia, Tomokazu Kusano, Dimitris Zacharoulis, Duncan Spalding, Madhava Pai, Long R. Jiao, and Kai W. Huang 2018. "A Systematic Review and Meta-Analysis Comparing Liver Resection with the Rf-Based Device Habib™-4X with the Clamp-Crush Technique" Cancers 10, no. 11: 428. https://doi.org/10.3390/cancers10110428

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