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Toxins, Volume 4, Issue 9

September 2012 - 8 articles

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Articles (8)

  • Article
  • Open Access
92 Citations
11,575 Views
23 Pages

18 September 2012

Oxylipins regulate Aspergillus development and mycotoxin production and are also involved in Aspergillus quorum sensing mechanisms. Despite extensive knowledge of how these oxylipins are synthesized and what processes they regulate, nothing is known...

  • Brief Report
  • Open Access
13 Citations
6,878 Views
11 Pages

18 September 2012

Staphylococcal enterotoxin B (SEB) and related exotoxins produced by Staphylococcus aureus are potent activators of the immune system and cause toxic shock in humans. Currently there is no effective treatment except for the use of intravenous immunog...

  • Article
  • Open Access
33 Citations
8,264 Views
19 Pages

Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities

  • Letícia B. Rocha,
  • Daniela E. Luz,
  • Claudia T. P. Moraes,
  • Andressa Caravelli,
  • Irene Fernandes,
  • Beatriz E. C. Guth,
  • Denise S. P. Q. Horton and
  • Roxane M. F. Piazza

18 September 2012

Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been developed for STEC diagnosi...

  • Review
  • Open Access
40 Citations
12,707 Views
19 Pages

Macrophage-Targeted Therapy: CD64-Based Immunotoxins for Treatment of Chronic Inflammatory Diseases

  • Dmitrij Hristodorov,
  • Radoslav Mladenov,
  • Michael Huhn,
  • Stefan Barth and
  • Theo Thepen

14 September 2012

Diseases caused by chronic inflammation (e.g., arthritis, multiple sclerosis and diabetic ulcers) are multicausal, thus making treatment difficult and inefficient. Due to the age-associated nature of most of these disorders and the demographic transi...

  • Article
  • Open Access
348 Citations
13,778 Views
13 Pages

12 September 2012

Between January 2009 and December 2011, a total of 7049 corn, soybean/soybean meal, wheat, dried distillers grains with solubles (DDGS) and finished feed samples were analyzed for the occurrence of aflatoxins (Afla), zearalenone (ZEN), deoxynivalenol...

  • Article
  • Open Access
13 Citations
7,887 Views
20 Pages

11 September 2012

Ochratoxin A (OTA) is considered to be a possible human urinary tract carcinogen, based largely on a rat model, but no molecular genetic changes in the rat carcinomas have yet been defined. The phosphorylated-S6 ribosomal protein is a marker indicati...

  • Article
  • Open Access
31 Citations
14,256 Views
10 Pages

Simultaneous Detection of Ricin and Abrin DNA by Real-Time PCR (qPCR)

  • Eva Felder,
  • Ilona Mossbrugger,
  • Mirko Lange and
  • Roman Wölfel

31 August 2012

Ricin and abrin are two of the most potent plant toxins known and may be easily obtained in high yield from the seeds using rather simple technology. As a result, both toxins are potent and available toxins for criminal or terrorist acts. However, as...

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Toxins - ISSN 2072-6651