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Clinics and Practice, Volume 13, Issue 1

2023 February - 29 articles

Cover Story: Subarachnoid, intraparenchymal, intraventricular hemorrhage (SAH, IH, IVH) and severe traumatic brain injury (TBI) are the common conditions requiring external ventricular drainage (EVD), which both represents life-saving treatment and controls intracranial pressure in any complicated acute brain injury with clinical manifestations. EVD can be continuous, as recommended by the principal international guidelines; or intermittent, i.e., less frequent and complicated by a clogged catheter and hemorrhage. EVD misplacement leads to brain edema and midline shift, and external lumbar drainage (ELD) could be the “extrema ratio” for refractory intracranial hypertension. Further, EVD weaning is crucial, and it can be rapid or gradual without differences in terms of ventricular–peritoneal shunting dependency. View this paper
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Articles (29)

  • Review
  • Open Access
18 Citations
11,270 Views
11 Pages

Notalgia Paresthetica Review: Update on Presentation, Pathophysiology, and Treatment

  • Christopher Robinson,
  • Evan Downs,
  • Yanet De la Caridad Gomez,
  • Chinonso Nduaguba,
  • Parker Woolley,
  • Giustino Varrassi,
  • Jatinder Gill,
  • Thomas T. Simopoulos,
  • Omar Viswanath and
  • Cyrus A. Yazdi

19 February 2023

Purpose of Review: Notalgia paresthetica (NP) is a chronic cutaneous neuropathy primarily characterized by localized pruritus and associated dysesthesias, including sensations of pain, numbness, and tingling. The sensory neuropathy characteristic of...

  • Article
  • Open Access
5 Citations
4,185 Views
10 Pages

Pushout Bond Strength of Root Fillings after Irrigation of Root Canals Utilizing Sodium Hypochlorite, Chlorhexidine, and Homeopathic Mother Tincture (Arnica Montana)

  • Unmesh Khanvilkar,
  • Hitesh Patil,
  • Siddhesh Bandekar,
  • Shirin Kshirsagar,
  • Ajinkya M. Pawar,
  • Dian Agustin Wahjuningrum,
  • Francesco Pagnoni,
  • Rodolfo Reda,
  • Alessio Zanza and
  • Luca Testarelli

17 February 2023

The pushout bond strength of root fillings at radicular dentin was investigated employing NaOCl, CHX, and homoeopathic mother tincture (Arnica montana) as an irrigant. Sixty human permanent single-rooted extracted teeth were decoronated. The root can...

  • Case Report
  • Open Access
1 Citations
2,806 Views
8 Pages

Combined Invasive Peripheral Nerve Stimulation in the Management of Chronic Post-Intracranial Disorder Headache: A Case Report

  • Athanasia Alexoudi,
  • Efstathios Vlachakis,
  • Stamatios Banos,
  • Konstantinos Oikonomou,
  • Panayiotis Patrikelis,
  • Anastasia Verentzioti,
  • Maria Stefanatou,
  • Stylianos Gatzonis,
  • Stefanos Korfias and
  • Damianos Sakas

17 February 2023

The introduction of ventricular shunts dramatically changed the outcome and quality of life of hydrocephalic patients. However, shunt surgery continues to be associated with numerous adverse events. Headache is one of the most common complications af...

  • Case Report
  • Open Access
7 Citations
2,836 Views
9 Pages

Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation

  • Claudia Manini,
  • Claudia Provenza,
  • Leire Andrés,
  • Igone Imaz,
  • Rosa Guarch,
  • Raffaelle Nunziata and
  • José I. López

16 February 2023

Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problem...

  • Opinion
  • Open Access
4 Citations
2,565 Views
8 Pages

Empowering Tennessee Pharmacists to Initiate PrEP Using Collaborative Pharmacy Practice Agreements

  • Alina Cernasev,
  • Rachel E. Barenie,
  • Breanne R. Wofford,
  • Jay Golden and
  • Crystal Walker

15 February 2023

Background: The uptake of Pre-Exposure Prophylaxis (PrEP) has revolutionized the fight against the Human Immunodeficiency Virus (HIV) epidemic. Consistent obstacles remain that have influenced the slow uptake of PrEP in the United States of America (...

  • Review
  • Open Access
24 Citations
7,984 Views
16 Pages

An Overview of Corneal Transplantation in the Past Decade

  • Mutali Musa,
  • Marco Zeppieri,
  • Ehimare S. Enaholo,
  • Ekele Chukwuyem and
  • Carlo Salati

14 February 2023

The cornea is a transparent avascular structure located in the front of the eye that refracts light entering the eyes and also serves as a barrier between the outside world and the internal contents of the eye. Like every other body part, the cornea...

  • Article
  • Open Access
31 Citations
9,113 Views
13 Pages

Quality of Life among Couples with a Fertility Related Diagnosis

  • Panagiota Dourou,
  • Kleanthi Gourounti,
  • Aikaterini Lykeridou,
  • Konstantina Gaitanou,
  • Nikolaos Petrogiannis and
  • Antigoni Sarantaki

9 February 2023

Fertility-related stress can negatively impact infertile couples’ quality of life (QoL). Most previous studies have concentrated on the effects of stress and infertility on individual persons, especially women, though infertility affects the Qo...

  • Communication
  • Open Access
1 Citations
2,473 Views
5 Pages

Increasing Risk of Tick-Borne Disease through Growth Stages in Ticks

  • Makoto Kondo,
  • Yoshiaki Matsushima,
  • Takehisa Nakanishi,
  • Shohei Iida,
  • Habe Koji and
  • Keiichi Yamanaka

6 February 2023

Rickettsia and Coxiella spp. are pathogens transmitted by ticks to humans. However, the developmental stage of the tick carrying the greatest risk of infection is unknown. Detection of pathogen-specific genes proves that ticks carrying Rickettsia or...

  • Review
  • Open Access
7 Citations
3,802 Views
16 Pages

Adipose Stem Cells in Modern-Day Ophthalmology

  • Mutali Musa,
  • Marco Zeppieri,
  • Ehimare S. Enaholo,
  • Carlo Salati and
  • Pier Camillo Parodi

4 February 2023

Stem cells (SCs) have evolved as an interesting and viable factor in ophthalmologic patient care in the past decades. SCs have been classified as either embryonic, mesenchymal, tissue-specific, or induced pluripotent cells. Multiple novel management...

  • Review
  • Open Access
32 Citations
27,538 Views
11 Pages

External Ventricular Drainage: A Practical Guide for Neuro-Anesthesiologists

  • Alessandro Bertuccio,
  • Stefano Marasco,
  • Yaroslava Longhitano,
  • Tatsiana Romenskaya,
  • Angela Elia,
  • Gianluca Mezzini,
  • Matteo Vitali,
  • Christian Zanza and
  • Andrea Barbanera

31 January 2023

External ventricular drainage is often considered a life-saving treatment in acute hydrocephalus. Given the large number of discussion points, the ideal management of EVD has not been completely clarified. The objective of this study was to review th...

  • Opinion
  • Open Access
8 Citations
12,433 Views
13 Pages

Pathophysiology-Based Management of Acute Heart Failure

  • Luigi Falco,
  • Maria Luigia Martucci,
  • Fabio Valente,
  • Marina Verrengia,
  • Giuseppe Pacileo and
  • Daniele Masarone

31 January 2023

Even though acute heart failure (AHF) is one of the most common admission diagnoses globally, its pathogenesis is poorly understood, and there are few effective treatments available. Despite an heterogenous onset, congestion is the leading contributo...

  • Case Report
  • Open Access
4 Citations
3,358 Views
6 Pages

30 January 2023

Anti-programmed death-1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint inhibitors (ICIs), combined with bevacizumab and platinum-based chemotherapy, have shown promising efficacy in treating metastatic non-squamous cell lung cancer in pha...

  • Article
  • Open Access
1 Citations
3,030 Views
10 Pages

Which Patients with Chronic Periprosthetic Joint Infection Are Less Suitable to Successful Two Stage Exchange Arthroplasty Surgery? A Retrospective Clinical Trial

  • Alberto Di Martino,
  • Gabriele Di Carlo,
  • Davide Pederiva,
  • Valentino Rossomando,
  • Federico Pilla,
  • Matteo Brunello,
  • Claudio D’Agostino,
  • Leonardo Tassinari,
  • Eleonora Zamparini and
  • Cesare Faldini

28 January 2023

Background: Two-stage exchange (TSE) arthroplasty is currently considered the gold standard for chronic periprosthetic joint infections (PJIs), despite a failure rate reported in up to 10% of patients. Little is known about the risk factors that may...

  • Case Report
  • Open Access
2 Citations
6,783 Views
13 Pages

28 January 2023

The incidence of psoriasis, an intractable long-lasting inflammatory skin disease, is increasing and has many complications and comorbidities. Approximately 14% of patients have psoriatic arthritis (PsA). Rheumatoid arthritis (RA) is not a rare disea...

  • Review
  • Open Access
5 Citations
3,306 Views
11 Pages

The Diagnostic Odyssey of Patients with Chronic Neuropathic Pain—Expert Opinion of Greek Pain Specialists

  • Persefoni Kritikou,
  • Athina Vadalouca,
  • Martina Rekatsina,
  • Giustino Varrassi and
  • Ioanna Siafaka

27 January 2023

The diagnosis of chronic neuropathic pain requires a laborious process and can be a very long journey for the patients, one that can be characterized as an “odyssey.” Our aim was to describe the “diagnostic odyssey” associated...

  • Review
  • Open Access
29 Citations
34,059 Views
11 Pages

Pathogenesis, Diagnostic Challenges, and Risk Factors of Pott’s Disease

  • Ira Glassman,
  • Kevin H. Nguyen,
  • Jane Giess,
  • Cheldon Alcantara,
  • Michelle Booth and
  • Vishwanath Venketaraman

25 January 2023

Tuberculosis (TB) prevalence is increasing in developed nations and continuing to cause significant mortality in low- and middle-income countries. As a result of the uptick in cases, there also exists an increased prevalence of extrapulmonary TB. TB...

  • Article
  • Open Access
1 Citations
2,371 Views
7 Pages

Impact of Japan’s State of Emergency Due to the COVID-19 Pandemic on Trends in Diabetes Care: A Descriptive and Retrospective Study

  • Akira Minoura,
  • Kouzou Murakami,
  • Masaaki Matoba,
  • Yoshinori Ito,
  • Yumi Kamijo and
  • Akatsuki Kokaze

16 January 2023

Objective: This study examined the impact of Japan’s state of emergency on trends in diabetes care during the coronavirus disease 2019 (COVID-19) pandemic. Design: A descriptive and retrospective study. Setting: Showa University Hospital, Japan...

  • Review
  • Open Access
14 Citations
4,428 Views
23 Pages

Preventing Respiratory Viral Diseases with Antimicrobial Peptide Master Regulators in the Lung Airway Habitat

  • Piyush Baindara,
  • Sriradha Ganguli,
  • Ranadhir Chakraborty and
  • Santi M. Mandal

16 January 2023

The vast surface area of the respiratory system acts as an initial site of contact for microbes and foreign particles. The whole respiratory epithelium is covered with a thin layer of the airway and alveolar secretions. Respiratory secretions contain...

  • Concept Paper
  • Open Access
4 Citations
4,018 Views
9 Pages

16 January 2023

The handling of incidental findings (IFs) in brain imaging studies has been a source of contention among scientists and bioethicists. A conceptual framework informed by diversity, equity, and inclusion (DEI) and distributive justice approaches, namel...

  • Review
  • Open Access
5 Citations
3,464 Views
14 Pages

Monkeypox 2022 Outbreak: How Alarming Is the Situation? Epidemiological and Clinical Review

  • Farah Marraha,
  • Ibtissam Al Faker,
  • Hanane Chahoub,
  • Youness Benyamna,
  • Najlae Rahmani and
  • Salim Gallouj

13 January 2023

Monkeypox is a disease caused by Orthopoxvirus, which also includes the smallpox virus. Several endemics have been reported on the African continent, typically in the western and central regions. However, since 13 May 2022, there have been several ca...

  • Article
  • Open Access
8 Citations
3,347 Views
14 Pages

Gelatin–Curcumin Nanocomposites as a Coating for Implant Healing Abutment: In Vitro Stability Investigation

  • Solmaz Maleki Dizaj,
  • Ali Torab,
  • Shadi Kouhkani,
  • Simin Sharifi,
  • Ramin Negahdari,
  • Sepideh Bohlouli,
  • Shirin Fattahi and
  • Sara Salatin

12 January 2023

Regarding the importance of preventing peri-implantitis in dental implants, the current study aimed to coat a healing abutment with gelatin–curcumin nanocomposites, and the stability of this coating on the healing abutment was evaluated. A cell...

  • Review
  • Open Access
13 Citations
6,879 Views
13 Pages

3 January 2023

(1) Background: Type 2 diabetes mellitus (T2DM) is a global disease with a compelling impact on developed and developing economies across the globe. The World Health Organization (WHO) (2020) reported a global prevalence of 8.5% in 2014 among adults...

  • Article
  • Open Access
1 Citations
2,191 Views
6 Pages

30 December 2022

Background: The aim of this retrospective uncontrolled article is to illustrate a technique of neurotomy of the sensitive branches of S1 S2 S3 in RFA that appears to result in a better success rate and longer-lasting pain relief. Methods: 40 patients...

  • Article
  • Open Access
4 Citations
4,677 Views
13 Pages

30 December 2022

Measuring satisfaction can be an essential method for evaluating and improving healthcare quality. Therefore, this survey aimed to determine university students’ satisfaction with dental care at the primary healthcare level and the factors that...

  • Article
  • Open Access
15 Citations
7,068 Views
11 Pages

Effects of Mediterranean Diet, DASH Diet, and Plant-Based Diet on Outcomes among End Stage Kidney Disease Patients: A Systematic Review and Meta-Analysis

  • Mariam Charkviani,
  • Charat Thongprayoon,
  • Supawit Tangpanithandee,
  • Pajaree Krisanapan,
  • Jing Miao,
  • Michael A. Mao and
  • Wisit Cheungpasitporn

28 December 2022

Background: The Mediterranean, Dietary Approach to Stop Hypertension (DASH), and plant-based diets may provide cardiovascular benefit to the general population. However, data on their effect on end stage kidney disease (ESKD) patients are limited. Th...

  • Review
  • Open Access
60 Citations
17,098 Views
19 Pages

27 December 2022

Over the years, immune checkpoint inhibitors (CPIs) have become a powerful treatment strategy in the field of cancer immunotherapy. In the last decade, the number of FDA-approved CPIs has been increasing prominently, opening new horizons for the trea...

  • Review
  • Open Access
8 Citations
3,306 Views
8 Pages

Advantages and Limitations in the Evaluation of the Neurological and Functional Deficit in Patients with Spinal Cord Injuries

  • Camelia Florentina Lascu,
  • Camelia Liana Buhaș,
  • Gabriel Mihai Mekeres,
  • Mădălin Bulzan,
  • Robert Bogdan Boț,
  • Georgiana Albina Căiță,
  • Ioan Bogdan Voiță and
  • Mihaela Dana Pogan

27 December 2022

(1) Background: Vertebro-medullary trauma (VMT) causes osteo-articular injuries in a varied anatomical lesion associated with multiple clinical manifestations and therapeutic indications. The neurological evaluation of patients who have suffered a sp...

  • Article
  • Open Access
3 Citations
4,834 Views
13 Pages

Depression in Male Inmates

  • Dimitrios Kastos,
  • Evangelos Dousis,
  • Afroditi Zartaloudi,
  • Niki Pavlatou,
  • Antonia Kalogianni,
  • Georgia Toulia,
  • Vasiliki Tsoulou and
  • Maria Polikandrioti

27 December 2022

Introduction: The prevalence of psychiatric morbidity is high among incarcerated individuals. Severe mental disorder is five to ten times higher among prisoners compared to the general population. Several factors are held to be responsible for the hi...

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Clin. Pract. - ISSN 2039-7283