Clinical Nursing and Quality of Healthcare

A special issue of Clinics and Practice (ISSN 2039-7283).

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 41231

Special Issue Editor


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Guest Editor
Department of Nursing, University of West Attica, Athens, Greece
Interests: surgical nursing; wound care; quality of life; negative pressure wound therapy; acute care nursing; evidence based nursing

Special Issue Information

Dear Colleagues,

Today, systems and health professionals are focusing more so than ever on the clinical management of emerging diseases. At the same time, in clinical practice, the possibilities that new therapeutic approaches and technologies represent are helping more than ever in the management of all patients, and especially critically ill patients. However, quality in the care of these patients must be addressed, as quality in health care is a key factor in daily clinical practice. It significantly determines the course of a disease and as a result determines the treatment options. We therefore invite the submission of research and review articles to this Special Issue regarding preclinical and clinical research findings on quality of care in patients at all levels of care.

Dr. Vasilopoulos George
Guest Editor

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Keywords

  • quality of care
  • quality of life
  • clinical practice
  • nursing
  • health care
  • health care systems
  • evidence-based nursing
  • evidence-based medicine

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Published Papers (12 papers)

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Editorial

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2 pages, 140 KiB  
Editorial
Quality in Contemporary Surgical Nursing
by Georgios Vasilopoulos
Clin. Pract. 2024, 14(4), 1214-1215; https://doi.org/10.3390/clinpract14040096 - 21 Jun 2024
Viewed by 1299
Abstract
Quality in healthcare is a multidimensional issue involving various features that depend on service performance and personal assessment (Stavropoulou et al [...] Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)

Research

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14 pages, 1116 KiB  
Article
Two Pregnancy Care Models in Poland—A Descriptive–Comparative Study
by Marta Gallas, Aleksandra Gaworska-Krzemińska and Katarzyna Pogorzelczyk
Clin. Pract. 2023, 13(5), 1146-1159; https://doi.org/10.3390/clinpract13050103 - 20 Sep 2023
Viewed by 1410
Abstract
Care for a pregnant woman can take various organizational forms. The World Health Organization (WHO) recommends leaders increase research into health systems. The aim of this is to manage the healthcare system in such a way as to provide beneficiaries with access to [...] Read more.
Care for a pregnant woman can take various organizational forms. The World Health Organization (WHO) recommends leaders increase research into health systems. The aim of this is to manage the healthcare system in such a way as to provide beneficiaries with access to high-quality services with limited financial resources. The study presented in this paper was conducted using a diagnostic survey on a group of 1642 Polish women in the traditional model of care (TM) and 3216 women in the Coordinated Care for Pregnant Women Program (CCP). Two research tools were used in this study. The first is a survey prepared by the National Health Fund, the second is an author’s survey. The results indicate that most women (85%) receiving care under the CCP received effective pain management, compared to 67% under the traditional care model (p < 0.001). In the CCP, women were significantly more likely to receive midwife assistance in infant care (90%) than women in the traditional care model (60%) (p < 0.001). Significantly more CCP patients want to return to the same hospital for their subsequent childbirth (74%) than women in the traditional model of care (43%) (p < 0.001). In patients’ opinion, the new CCP model is superior in meeting their needs and providing higher-quality services. However, educating women that an obstetrician-gynecologist and a midwife can manage their pregnancy is still necessary. In addition to the CCP program, special attention should be paid to available pain management during childbirth since the use of analgesia is still insufficient in Polish hospitals. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
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8 pages, 458 KiB  
Article
The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial
by Karoline Riedler, Andrzej Hecker, Birgit Bauer, Christa Tax, Daniel Georg Gmainer, Anna-Lisa Pignet, Lars-Peter Kamolz and David Benjamin Lumenta
Clin. Pract. 2023, 13(3), 648-655; https://doi.org/10.3390/clinpract13030059 - 25 May 2023
Viewed by 2343
Abstract
Background and Objectives: Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar [...] Read more.
Background and Objectives: Essential oils are a complementary treatment and can play an important role in scar care. The aim of this study was to evaluate and compare the efficacy of a new essential oil (regeneration oil) with a control group on scar quality in healed split-thickness skin graft donor sites. Materials and Methods: A single-center blinded randomized controlled study was performed on 30 patients with healed split-thickness skin graft donor site. The patients were randomly allocated into blended regeneration oil (n = 14) and pure almond oil (n = 16) groups. Application of the assigned oil occurred twice a day for 6 months. Scarring (Patient and Observer Scar Assessment Scale), itching (ITCH Assessment Scale) and scar discoloration (colorimetry) of the donor sites were assessed after 1, 3 and 6 months. Results: We found no statistically significant differences between the groups in any applied parameter. We observed comparable outcomes (scar quality, itchiness, colorit) in healed split-thickness skin graft donor sites for both oils. Conclusions: Regeneration oil and control oil presented comparable results regarding scar quality, itchiness and colorit in healed split-thickness skin graft donor sites after 6 months of application. Both oils are suitable for skin/scar care in split-thickness skin graft donor sites. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
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17 pages, 299 KiB  
Article
Quality of Life in Patients Undergoing Percutaneous Coronary Intervention
by Vasiliki Tsoulou, Georgios Vasilopoulos, Theodore Kapadochos, Niki Pavlatou, Antonia Kalogianni, Georgia Toulia, Evangellos Dousis, George Panoutsopoulos, Michael Kourakos and Maria Polikandrioti
Clin. Pract. 2023, 13(3), 621-637; https://doi.org/10.3390/clinpract13030057 - 17 May 2023
Cited by 2 | Viewed by 2309
Abstract
Introduction: Percutaneous coronary intervention (PCI) is a non-surgical invasive procedure to treat coronary artery occlusion. The quality of life (QoL) is a way to measure the impact of illness and additionally its treatments to traditional measures of clinical outcomes. Purpose: The aim of [...] Read more.
Introduction: Percutaneous coronary intervention (PCI) is a non-surgical invasive procedure to treat coronary artery occlusion. The quality of life (QoL) is a way to measure the impact of illness and additionally its treatments to traditional measures of clinical outcomes. Purpose: The aim of the present study was to explore the levels of QoL pre-PCI, 6 and 12 months after PCI, as well as the factors associated with the QoL pre-PCI. Methods: In the present study, 100 patients undergoing PCI were enrolled. Data were collected through the completion of the SF-36 Health Survey (SF-36), which included participants’ characteristics. The statistical significance level was p < 0.05. Results: Patients had moderate levels of QoL at baseline, with a median general health score of 45 (IQR: 30–65). A gradual statistically significant increase in scores was observed in all subcategories of the patients’ QoL at 6 and 12 months after PCI (p < 0.001). A greater increase in scores was observed in physical functioning, physical role, emotional role and social functionality. In terms of the pre-PCI phase, it was found that physical functionality was statistically significantly associated with educational level (p = 0.005), occupation (p = 0.026) and whether the patients had children (p = 0.041). The physical and emotional role was significantly associated with gender (p = 0.046 and p = 0.040) and educational level (p = 0.030 and p = 0.001). Energy–fatigue was significantly associated with gender (p = 0.001), age (p = 0.028), marital status (p = 0.001), educational level (p = 0.001), whether the patients had children (p= 0.012) and other diseases (p = 0.001). Emotional well-being was significantly associated with family history of coronary artery disease (p = 0.011) and the frequency of physical exercise (p = 0.001). Social functioning was significantly associated with gender (p = 0.033), marital status (p = 0.034) and educational level (p = 0.002). Pain was not found to be significantly associated with patients’ demographics. General health was significantly associated with gender (p = 0.003), age (p = 0.043), educational level (p = 0.001), other diseases (p = 0.005) and the frequency of physical exercise (p = 0.001). Conclusion: Information about the QoL of PCI and its determinants is important to define an effective and comprehensive care plan. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
9 pages, 737 KiB  
Article
Investigation of the Quality of Life of Patients with Gastrointestinal Issues Treated in the Surgical Clinic of a Regional General Hospital in Greece
by Nikos Rikos, Chara Frantzeskaki, Maria Fragiadaki, Anna Kassotaki, Andreas Mpalaskas, Manolis Linardakis and Georgios Vasilopoulos
Clin. Pract. 2023, 13(2), 520-528; https://doi.org/10.3390/clinpract13020048 - 12 Apr 2023
Viewed by 1894
Abstract
As disorders of the gastrointestinal system are among the most prevalent, had a significant impact on patients’ quality of life (QoL). This study aimed to investigate the QoL of 83 patients treated in the surgical clinic of a regional general hospital in Crete-Greece. [...] Read more.
As disorders of the gastrointestinal system are among the most prevalent, had a significant impact on patients’ quality of life (QoL). This study aimed to investigate the QoL of 83 patients treated in the surgical clinic of a regional general hospital in Crete-Greece. They recruited from April-to-June 2021 using the 36-Item Short Form Survey scale (SF-36) and the Spielberger State-Trait Anxiety Inventory (STAI). Logistic regression analysis was performed to evaluate the QoL in relation to patients’ characteristics. The 50.6% were men with mean age of all the 55.0 years. Mental Health was found with highest mean score in relation to Role Physical (p < 0.001) and the Mental Component higher than the Physical (p = 0.029) while 68.7% of patients had high State Anxiety score. For each added year of age, the odds ratio of a moderate-to-high Physical Component was significantly decreased (OR = 0.95, p = 0.012) as married/partnered patients had higher odds of a moderate-to-high Mental Component (OR = 6.59, p = 0.006). Those with high state anxiety had lower odds of a moderate-to-high Mental Component (OR = 0.16, p = 0.005). Action is necessary on a clinical or individual level, guided by health professionals, to promote appropriate dietary choices and interventions for the avoidance of behaviors that could harm or endanger patients’ health. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
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13 pages, 264 KiB  
Article
The Psychological and Professional Burden Experienced by Nurses Who Worked in COVID-19 Clinics during the Pandemic: A Content Analysis
by Areti Stavropoulou, Maria Prasianaki, Dimitris Papageorgiou, Evridiki Kaba, Evdokia Misouridou, Chrysoula Dafogianni, Georgia Gerogianni and Martha Kelesi
Clin. Pract. 2023, 13(2), 422-434; https://doi.org/10.3390/clinpract13020038 - 9 Mar 2023
Cited by 2 | Viewed by 2531
Abstract
Introduction: Since the beginning of the pandemic, nurses have played a key role in providing care for COVID-19 patients. Infection risk and fear, use of personal protective equipment, and social isolation were related to high levels of stress and extreme psychological drain among [...] Read more.
Introduction: Since the beginning of the pandemic, nurses have played a key role in providing care for COVID-19 patients. Infection risk and fear, use of personal protective equipment, and social isolation were related to high levels of stress and extreme psychological drain among front-line healthcare providers. Aim: The aim of this study was to explore how front-line nurses experienced psychological and professional burdens during the coronavirus outbreak. Material and Methods: The study used a qualitative research design. Semi-structured interviews were applied as the method of data collection. Ten nurses from COVID-19 wards and units of two general public hospitals participated in the study. A content analysis approach was employed to analyze the data. Results: Data analysis revealed two main categories, namely: (A) front-line experience “From fear to empowerment”, and (B) caring and management “From powerlessness to adaptation”. Eight sub-categories were developed and included within the corresponding main categories. The study’s findings demonstrated that the pandemic caused significant psychological and professional strain on front-line nurses, with feelings of fear, anxiety, and uncertainty predominating. Nonetheless, the process of adaptation and adjustment brought about sentiments of self-actualization and empowerment. Conclusions: A thorough understanding of the psychological and professional burden experienced by the front-line nurses is crucial to ensure that nurses receive appropriate support and that quality care is sustained under highly demanding healthcare conditions. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
12 pages, 1201 KiB  
Article
A Conceptual Model to Strengthen Integrated Management of HIV and NCDs among NIMART-Trained Nurses in Limpopo Province, South Africa
by Nthuseni Sharon Murudi-Manganye, Lufuno Makhado and Leepile Alfred Sehularo
Clin. Pract. 2023, 13(2), 410-421; https://doi.org/10.3390/clinpract13020037 - 9 Mar 2023
Cited by 2 | Viewed by 2093
Abstract
Integrated management of human immune deficiency virus (HIV) and non-communicable diseases (NCDs) in primary health care facilities remains a challenge. Despite research that has been conducted in South Africa, it is evident that in Limpopo Province there are slits in the implementation thereof. [...] Read more.
Integrated management of human immune deficiency virus (HIV) and non-communicable diseases (NCDs) in primary health care facilities remains a challenge. Despite research that has been conducted in South Africa, it is evident that in Limpopo Province there are slits in the implementation thereof. There is a need to develop a conceptual model to guide in strengthening the clinical competence of nurse-initiated management of antiretroviral therapy (NIMART)-trained nurses to implement the integrated management of HIV and NCDs to improve clinical outcomes of patients with the dual burden of diseases in Limpopo Province, South Africa. This study aimed to develop a conceptual model to strengthen the implementation of integrated management of HIV and NCDs amongst NIMART nurses to improve clinical outcomes of patients with the dual burden of communicable and non-communicable diseases in Limpopo Province, South Africa. An explanatory, sequential, mixed-methods research design was followed. Data were collected from patient records and the skills audit of 25 Primary Health Care (PHC) facilities and from 28 NIMART trained nurses. Donabedian’s structure process outcome model and Miller’s pyramid of clinical competence provided a foundation in the development of the conceptual model. The study revealed a need to develop a conceptual model to strengthen the implementation of integrated HIV and NCDs implementation in PHC, as evidenced by differences in the management of HIV and NCDs. Conclusion: The study findings were conceptualised to describe and develop a model needed to strengthen the implementation of integrated management of HIV and NCDs amongst NIMART nurses working in PHC facilities. The study was limited to Limpopo Province; the model must be implemented in conjunction with the available frameworks to achieve better clinical outcomes. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
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10 pages, 255 KiB  
Communication
Measuring Importance of Physical Self-Care Behavior in Patients with Heart Failure: Validation and Reliability Analysis of 14-item IPSC Scale
by Athanasia Tsami, Ioannis Koutelekos, Georgia Gerogianni, Niki Pavlatou, Antonia Kalogianni, Theodore Kapadohos, Georgia Toulia and Maria Polikandrioti
Clin. Pract. 2023, 13(2), 357-366; https://doi.org/10.3390/clinpract13020032 - 24 Feb 2023
Viewed by 2037
Abstract
Introduction: Heart failure (HF) is a complex clinical syndrome associated with increased disability, morbidity and mortality globally. HF is characterized by recurrent exacerbations and a high rate of hospital readmissions. Self-care is a crucial component of treatment. The way patients assess the importance [...] Read more.
Introduction: Heart failure (HF) is a complex clinical syndrome associated with increased disability, morbidity and mortality globally. HF is characterized by recurrent exacerbations and a high rate of hospital readmissions. Self-care is a crucial component of treatment. The way patients assess the importance of self-care may shed light on planning effective individualized interventions. The aim of this study was to conduct a validity and reliability analysis of the new 14-item IPSC scale, which measures how important HF patients consider their physical self-care behavior (IPSC, Importance of Physical Self-Care). Material and Methods: The 14-item IPSC scale was created by the researchers to explore how important HF patients consider their physical self-care behavior. The validation of the IPSC scale included face and content validity, construct validity, internal consistency, repeatability and discriminant validity. Patients’ characteristics were also included. Results: In the present study, 52 hospitalized HF patients were enrolled, of whom 55.8% were female, 34.6% above 70 years old, 48.1% of NYHA class III and 32.7% suffered this illness from 6 to 10 years. The total IPSC score had a possible range of 14–56, with higher scores indicating a low importance of self-care. The descriptive statistics in the IPSC scale showed a mean score of 27.9 ± 4.9 and a median score of 29, indicating that HF patients evaluated self-care behavior as moderately important. All items were found to be statistically significantly correlated with total scale scores (p ≤ 0.05), with correlation coefficients rho > 0.250, indicating moderate to strong correlations and meaning that all items are important in the calculation of the final score (construct validity). The internal consistency of the items that constituted the total score was found to be high (Cronbach’s a > 0.7). Furthermore, it was found that scores had high repeatability (p ≤ 0.001 and ICCs > 0.7). Regarding discriminant validity, a statistically significant association was observed between the importance of physical self-care behavior and both years suffering the illness (p = 0.007) and the NYHA class (p = 0.030). Conclusion: The 14-item IPSC scale is a reliable instrument that help nurses in clinical settings to gain a better and prompt understanding of the importance which patients invest in their physical self-care behavior. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
13 pages, 289 KiB  
Article
Quality of Life among Couples with a Fertility Related Diagnosis
by Panagiota Dourou, Kleanthi Gourounti, Aikaterini Lykeridou, Konstantina Gaitanou, Nikolaos Petrogiannis and Antigoni Sarantaki
Clin. Pract. 2023, 13(1), 251-263; https://doi.org/10.3390/clinpract13010023 - 9 Feb 2023
Cited by 8 | Viewed by 4442
Abstract
Fertility-related stress can negatively impact infertile couples’ quality of life (QoL). Most previous studies have concentrated on the effects of stress and infertility on individual persons, especially women, though infertility affects the QoL of both spouses. Our research aimed to investigate the roles [...] Read more.
Fertility-related stress can negatively impact infertile couples’ quality of life (QoL). Most previous studies have concentrated on the effects of stress and infertility on individual persons, especially women, though infertility affects the QoL of both spouses. Our research aimed to investigate the roles of infertility and stress in couples’ quality of life as a single unit. The research sample consisted of 202 spouses, i.e., 101 couples, with a mean age of 39.5 years (SD = 4.9 years) undergoing fertility treatment at Athens Naval Hospital-Assisted Reproduction Unit. Data collection was completed via self-administered questionnaires: the FertiQoL International Questionnaire for measuring the quality of life in infertility and The Demographic Information and Medical History Questionnaire. Data collection was conducted between January and November 2022. Quantitative variables are expressed as mean values (standard deviation) and as median interquartile range, and qualitative variables are expressed as absolute and relative frequencies. Pearson’s (r) and Spearman’s (rho) correlations coefficients were used to explore the association of two continuous variables. Multiple linear regression analysis was used with dependence on the Ferti-QoL’s subscales. The regression equation included terms for participants’ demographics and information from their medical history. Adjusted regression coefficients (β) with standard errors (SE) were computed from the results of the linear regression analyses. All reported p values are two-tailed. Statistical significance was set to p < 0.05, and analyses were conducted using SPSS statistical software (version 22.0). We found that greater anxiety and depression were significantly associated with worse quality of life. Additionally, quality of life, according to Ferti-QoL, was significantly worse in women, participants with a high level of education, those with greater depressive symptoms, and those with greater state scores. Findings of this study highlight the need for implementing interventions of supportive care methods, counseling, stress reduction methods, and improving the fertility-related quality of life of infertile couples. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
13 pages, 276 KiB  
Article
Depression in Male Inmates
by Dimitrios Kastos, Evangelos Dousis, Afroditi Zartaloudi, Niki Pavlatou, Antonia Kalogianni, Georgia Toulia, Vasiliki Tsoulou and Maria Polikandrioti
Clin. Pract. 2023, 13(1), 1-13; https://doi.org/10.3390/clinpract13010001 - 27 Dec 2022
Viewed by 3450
Abstract
Introduction: The prevalence of psychiatric morbidity is high among incarcerated individuals. Severe mental disorder is five to ten times higher among prisoners compared to the general population. Several factors are held to be responsible for the high prevalence of depression in prison: mainly [...] Read more.
Introduction: The prevalence of psychiatric morbidity is high among incarcerated individuals. Severe mental disorder is five to ten times higher among prisoners compared to the general population. Several factors are held to be responsible for the high prevalence of depression in prison: mainly poor living conditions (narrow room, loss of privacy), limited interpersonal relationships, and lack of mental health access. Inmates are at increased risk of all-cause mortality, suicide, self-harm, violence, and victimization while those with mental disorders are involved in conflicts and are more likely to be charged with prison rules. Purpose: To explore depression among male inmates. Methods and material: In the study, 101 male inmates were enrolled. Data were collected by the completion of a “self-rating depression scale (SDS)-Zung” which included participants’ characteristics. The statistical significance level was p < 0.05. Results: Of the 101 participants, 51.4% of inmates were under 40 years old, 54.5% were married, 45.6% had been convicted of homicide and 38.6% had a life sentence. Normal depression levels were experienced by 62.4% of the participants, while 21.8% were mildly depressed, 14.9% were moderately depressed and 1.0% severely depressed. Foreign prisoners had statistically significant higher scores of depression compared to Greeks (median 48 vs. 45, p = 0.012); those suffering from a chronic disease compared to those who did not (median 48 vs. 45, p = 0.038); those who had spent time in solitary confinement compared to those who had not (median 46 vs. 43.5, p = 0.038) as well as those who had not considered harming themselves compared to those who had thought of it (median 46 vs. 44, p = 0.017). Conclusion: Given that prison populations are marginalized and deprived of the rights that people in the community benefit from, establishing the prevalence of depression in male inmates and its associated characteristics may help to formulate recommendations for future prison health care services. Clinical, research, and policy efforts are needed to improve prison mental health. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
14 pages, 285 KiB  
Article
What Quality of Care Means? Exploring Clinical Nurses’ Perceptions on the Concept of Quality Care: A Qualitative Study
by Areti Stavropoulou, Michael Rovithis, Martha Kelesi, George Vasilopoulos, Evangelia Sigala, Dimitrios Papageorgiou, Maria Moudatsou and Sofia Koukouli
Clin. Pract. 2022, 12(4), 468-481; https://doi.org/10.3390/clinpract12040051 - 30 Jun 2022
Cited by 20 | Viewed by 6923
Abstract
Quality is a multidimensional issue involving various features that depend on service performance and personal assessment. Clarifying the concept of quality is essential in order to further facilitate the understanding and improvement of quality in healthcare. The purpose of this study was to [...] Read more.
Quality is a multidimensional issue involving various features that depend on service performance and personal assessment. Clarifying the concept of quality is essential in order to further facilitate the understanding and improvement of quality in healthcare. The purpose of this study was to investigate how clinical nurses, providing care to adult medical patients, perceive and define the concept of quality nursing care. A descriptive qualitative research design was applied. A purposive sampling strategy was used to recruit nurses from the clinical sector of a general public hospital in Athens, Greece. Ten female nurses from the medical sector participated the study. Data collection was conducted through in-depth, semi-structured interviews. Conventional content analysis was used to analyze the verbatim data. Four categories were revealed from the data analysis, namely: (a) “Quality care is holistic care”, (b) “Good care is an interpersonal issue”, (c) “Leadership is crucial”, and (d) “Best care is our responsibility”. Quality care was defined as holistic care, addressing all patient needs with competency and aiming for the best patient outcomes. It was associated with communication, teamwork, good leadership, and personal commitment. By developing an in-depth and mutual understanding about what quality means, nurse leaders and practitioners may collaborate in finding common paths to support quality interventions and enhance quality nursing care in clinical practice. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)

Review

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20 pages, 1644 KiB  
Review
Clinical Research in Prehospital Care: Current and Future Challenges
by Jonathan Cimino and Claude Braun
Clin. Pract. 2023, 13(5), 1266-1285; https://doi.org/10.3390/clinpract13050114 - 23 Oct 2023
Cited by 5 | Viewed by 8660
Abstract
Prehospital care plays a critical role in improving patient outcomes, particularly in cases of time-sensitive emergencies such as trauma, cardiac failure, stroke, bleeding, breathing difficulties, systemic infections, etc. In recent years, there has been a growing interest in clinical research in prehospital care, [...] Read more.
Prehospital care plays a critical role in improving patient outcomes, particularly in cases of time-sensitive emergencies such as trauma, cardiac failure, stroke, bleeding, breathing difficulties, systemic infections, etc. In recent years, there has been a growing interest in clinical research in prehospital care, and several challenges and opportunities have emerged. There is an urgent need to adapt clinical research methodology to a context of prehospital care. At the same time, there are many barriers in prehospital research due to the complex context, posing unique challenges for research, development, and evaluation. Among these, this review allows the highlighting of limited resources and infrastructure, ethical and regulatory considerations, time constraints, privacy, safety concerns, data collection and analysis, selection of a homogeneous study group, etc. The analysis of the literature also highlights solutions such as strong collaboration between emergency medical services (EMS) and hospital care, use of (mobile) health technologies and artificial intelligence, use of standardized protocols and guidelines, etc. Overall, the purpose of this narrative review is to examine the current state of clinical research in prehospital care and identify gaps in knowledge, including the challenges and opportunities for future research. Full article
(This article belongs to the Special Issue Clinical Nursing and Quality of Healthcare)
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