Bevacizumab-Induced Thrombotic Microangiopathy (TMA) in Metastatic Lung Adenocarcinoma Patients Receiving Nivolumab Combined with Bevacizumab, Carboplatin and Paclitaxel: Two Case Reports
Abstract
:1. Clinical Practice Points
- Drug-induced nephrotoxicity is an uncommon but threatening adverse effect when using ICIs combined with bevacizumab and chemotherapy.
- A kidney biopsy is indicated for metastatic non-squamous cell lung cancer patients experiencing nephrotoxicity during this combination therapy.
2. Introduction
3. Case Presentation
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Hsu, P.-C.; Chen, T.-D.; Tsai, T.-Y.; Yang, C.-T. Bevacizumab-Induced Thrombotic Microangiopathy (TMA) in Metastatic Lung Adenocarcinoma Patients Receiving Nivolumab Combined with Bevacizumab, Carboplatin and Paclitaxel: Two Case Reports. Clin. Pract. 2023, 13, 200-205. https://doi.org/10.3390/clinpract13010018
Hsu P-C, Chen T-D, Tsai T-Y, Yang C-T. Bevacizumab-Induced Thrombotic Microangiopathy (TMA) in Metastatic Lung Adenocarcinoma Patients Receiving Nivolumab Combined with Bevacizumab, Carboplatin and Paclitaxel: Two Case Reports. Clinics and Practice. 2023; 13(1):200-205. https://doi.org/10.3390/clinpract13010018
Chicago/Turabian StyleHsu, Ping-Chih, Tai-Di Chen, Tsung-Yu Tsai, and Cheng-Ta Yang. 2023. "Bevacizumab-Induced Thrombotic Microangiopathy (TMA) in Metastatic Lung Adenocarcinoma Patients Receiving Nivolumab Combined with Bevacizumab, Carboplatin and Paclitaxel: Two Case Reports" Clinics and Practice 13, no. 1: 200-205. https://doi.org/10.3390/clinpract13010018