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Open AccessReview

Targeting Groups Employed in Selective Dendrons and Dendrimers

Faculty of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo 05508-000, Brazil
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Pharmaceutics 2018, 10(4), 219; https://doi.org/10.3390/pharmaceutics10040219
Received: 4 September 2018 / Revised: 19 October 2018 / Accepted: 24 October 2018 / Published: 8 November 2018
(This article belongs to the Special Issue Dendrimers in Nanomedical Applications: Update and Future Directions)
The design of compounds with directed action to a defined organ or tissue is a very promising approach, since it can decrease considerably the toxicity of the drug/bioactive compound. For this reason, this kind of strategy has been greatly important in the scientific community. Dendrimers, on the other hand, comprise extremely organized macromolecules with many peripheral functionalities, stepwise controlled synthesis, and defined size. These nanocomposites present several biological applications, demonstrating their efficiency to act in the pharmaceutical field. Considering that, the main purpose of this review was describing the potential of dendrons and dendrimers as drug targeting, applying different targeting groups. This application has been demonstrated through interesting examples from the literature considering the last ten years of publications. View Full-Text
Keywords: dendrons; dendrimers; targeting groups; biomedical application dendrons; dendrimers; targeting groups; biomedical application
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MDPI and ACS Style

Vieira Gonzaga, R.; Da Silva Santos, S.; Da Silva, J.V.; Campos Prieto, D.; Feliciano Savino, D.; Giarolla, J.; Igne Ferreira, E. Targeting Groups Employed in Selective Dendrons and Dendrimers. Pharmaceutics 2018, 10, 219.

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