Next Article in Journal
Targeting Groups Employed in Selective Dendrons and Dendrimers
Next Article in Special Issue
The Combined Effects of Co-Culture and Substrate Mechanics on 3D Tumor Spheroid Formation within Microgels Prepared via Flow-Focusing Microfluidic Fabrication
Previous Article in Journal
A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route
Previous Article in Special Issue
Complex Polymeric Architectures Self-Assembling in Unimolecular Micelles: Preparation, Characterization and Drug Nanoencapsulation
Open AccessFeature PaperReview

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery

1
Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Patras, 26504 Rio-Patras, Greece
2
Foundation for Research and Technology Hellas, Institute of Chemical Engineering, FORTH/ICE-HT, 26504 Rio-Patras, Greece
*
Authors to whom correspondence should be addressed.
Pharmaceutics 2018, 10(4), 218; https://doi.org/10.3390/pharmaceutics10040218
Received: 22 October 2018 / Revised: 1 November 2018 / Accepted: 3 November 2018 / Published: 6 November 2018
(This article belongs to the Special Issue Micro and Nano Encapsulation Techniques)
The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of engineered-exosomes or exosome-mimetics, which may be artificial (liposomal) or cell-derived vesicles, as advanced platforms for targeted drug delivery. Here, we provide the current state-of-the-art of using exosome or exosome-inspired systems for drug delivery. We review the various approaches investigated and the shortcomings of each approach. Finally the challenges which have been identified to date in this field are summarized. View Full-Text
Keywords: liposomes; exosomes; extracellular vesicles; drug delivery; drug targeting; bioinspired systems; engineered systems liposomes; exosomes; extracellular vesicles; drug delivery; drug targeting; bioinspired systems; engineered systems
Show Figures

Figure 1

MDPI and ACS Style

Antimisiaris, S.G.; Mourtas, S.; Marazioti, A. Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery. Pharmaceutics 2018, 10, 218.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop