You are currently viewing a new version of our website. To view the old version click .

Viruses, Volume 15, Issue 4

April 2023 - 217 articles

Cover Story: The use of molecular models has been combined for the first time with experimental in vitro studies, and, as a result, has led to the discovery that one of the most prescribed drugs globally, aspirin, might also become a new efficient treatment for bunyavirus infections. As a safe, easily administrable and inexpensive drug, our discovery illustrates the large potential applications of repurposing aspirin to fight against viruses beyond SARS-CoV-2. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (217)

  • Article
  • Open Access
7 Citations
3,302 Views
15 Pages

Identification and Molecular Characterization of a Novel Carlavirus Infecting Chrysanthemum morifolium in China

  • Jiapeng Li,
  • Xiaoyin Wu,
  • Hui Liu,
  • Xiaomei Wang,
  • Shaokui Yi,
  • Xueting Zhong,
  • Yaqin Wang and
  • Zhanqi Wang

21 April 2023

Chrysanthemum (Chrysanthemum morifolium) is an important ornamental and medicinal plant suffering from many viruses and viroids worldwide. In this study, a new carlavirus, tentatively named Chinese isolate of Carya illinoinensis carlavirus 1 (CiCV1-C...

  • Article
  • Open Access
3 Citations
2,998 Views
12 Pages

Identification of a Conserved, Linear Epitope on VP3 of Enterovirus A Species Recognized by a Broad-Spectrum Monoclonal Antibody

  • Lie Fu,
  • Xiao-Yu Zhang,
  • Wei-Ping Jin,
  • Chen Wang,
  • Sha-Sha Qian,
  • Meng-Jun Wang,
  • Wen-Hui Wang,
  • Sheng-Li Meng,
  • Jing Guo and
  • Ze-Jun Wang
  • + 2 authors

21 April 2023

Outbreaks of hand, foot and mouth disease (HFMD) have occurred frequently in the Asian-Pacific region over the last two decades, caused mainly by the serotypes in Enterovirus A species. High-quality monoclonal antibodies (mAbs) are needed to improve...

  • Article
  • Open Access
7 Citations
4,041 Views
19 Pages

The Synthetic Opioid Fentanyl Increases HIV Replication and Chemokine Co-Receptor Expression in Lymphocyte Cell Lines

  • Janani Madhuravasal Krishnan,
  • Ling Kong,
  • Rebekah Karns,
  • Mario Medvedovic,
  • Kenneth E. Sherman and
  • Jason T. Blackard

21 April 2023

Background: In the United States, the illicit use of synthetic opioids such as fentanyl has led to a serious public health crisis. Synthetic opioids are known to enhance viral replication and to suppress immunologic responses, but their effects on HI...

  • Article
  • Open Access
15 Citations
4,574 Views
15 Pages

Effectiveness, Tolerability and Prescribing Choice of Antiviral Molecules Molnupiravir, Remdesivir and Nirmatrelvir/r: A Real-World Comparison in the First Ten Months of Use

  • Cosmo Del Borgo,
  • Silvia Garattini,
  • Carolina Bortignon,
  • Anna Carraro,
  • Daniela Di Trento,
  • Andrea Gasperin,
  • Alessandra Grimaldi,
  • Sara Giovanna De Maria,
  • Sara Corazza and
  • Tiziana Tieghi
  • + 15 authors

21 April 2023

In 2022, three antiviral drugs—molnupiravir, remdesivir and nirmatrelvir/ritonavir—were introduced for treatment of mild-to-moderate COVID-19 in high-risk patients. The aim of this study is the evaluation of their effectiveness and tolera...

  • Brief Report
  • Open Access
4 Citations
2,724 Views
7 Pages

Lipid Accumulation in Host Cells Promotes SARS-CoV-2 Replication

  • Tatjana Seitz,
  • Christian Setz,
  • Pia Rauch,
  • Ulrich Schubert and
  • Claus Hellerbrand

21 April 2023

Coronavirus disease-19 (COVID-19) is still affecting the lives of people around the globe and remains a major public health threat. Lipid levels in the host cells have been shown to promote SARS-CoV-2 replication, and since the start of COVID-19 pand...

  • Article
  • Open Access
3 Citations
2,927 Views
10 Pages

Epidemiologic and Clinical Characteristics of Human Bocavirus Infection in Children with or without Acute Gastroenteritis in Acre, Northern Brazil

  • Fábyla D’ Tácia Brito Trindade,
  • Endrya Socorro Foro Ramos,
  • Patrícia Santos Lobo,
  • Jedson Ferreira Cardoso,
  • Edvaldo Tavares Penha Júnior,
  • Delana Andreza Melo Bezerra,
  • Mayara Annanda Oliveira Neves,
  • Jorge Alberto Azevedo Andrade,
  • Monica Cristina Moraes Silva and
  • Joana D’Arc Pereira Mascarenhas
  • + 2 authors

21 April 2023

Human bocavirus (HBoV) is an emerging virus detected around the world that may be associated with cases of acute gastroenteritis (AGE). However, its contribution to AGE has not been elucidated. This study aimed to describe the frequency, clinical fea...

  • Article
  • Open Access
2 Citations
2,290 Views
13 Pages

21 April 2023

Human cytomegalovirus (CMV) has evolved to replicate while causing minimal damage, maintain life-long latency, reactivate sub-clinically, and, in spite of robust host immunity, produce and shed infectious virus in order to transmit to new hosts. The...

  • Article
  • Open Access
3 Citations
3,113 Views
15 Pages

Human Papillomavirus Infections and Increased Risk of Incident Osteoporosis: A Nationwide Population-Based Cohort Study

  • Kevin Sheng-Kai Ma,
  • Ning-Chien Chin,
  • Ting-Yu Tu,
  • Yao-Cheng Wu,
  • Hei-Tung Yip,
  • James Cheng-Chung Wei and
  • Ren-in Chang

21 April 2023

Patients with viral infections are susceptible to osteoporosis. This cohort study investigated the correlation between human papillomavirus (HPV) infections and the risk of osteoporosis via 12,936 patients with new-onset HPV infections and propensity...

  • Article
  • Open Access
17 Citations
5,052 Views
19 Pages

Metagenomic Detection of Divergent Insect- and Bat-Associated Viruses in Plasma from Two African Individuals Enrolled in Blood-Borne Surveillance

  • Gregory S. Orf,
  • Ana Olivo,
  • Barbara Harris,
  • Sonja L. Weiss,
  • Asmeeta Achari,
  • Guixia Yu,
  • Scot Federman,
  • Dora Mbanya,
  • Linda James and
  • Samuel Mampunza
  • + 4 authors

21 April 2023

Metagenomic next-generation sequencing (mNGS) has enabled the high-throughput multiplexed identification of sequences from microbes of potential medical relevance. This approach has become indispensable for viral pathogen discovery and broad-based su...

  • Review
  • Open Access
122 Citations
15,335 Views
36 Pages

Current Clinical Landscape and Global Potential of Bacteriophage Therapy

  • Nicole Marie Hitchcock,
  • Danielle Devequi Gomes Nunes,
  • Job Shiach,
  • Katharine Valeria Saraiva Hodel,
  • Josiane Dantas Viana Barbosa,
  • Leticia Alencar Pereira Rodrigues,
  • Brahm Seymour Coler,
  • Milena Botelho Pereira Soares and
  • Roberto Badaró

21 April 2023

In response to the global spread of antimicrobial resistance, there is an increased demand for novel and innovative antimicrobials. Bacteriophages have been known for their potential clinical utility in lysing bacteria for almost a century. Social pr...

of 22

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915