Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network
Abstract
:1. Introduction
2. Patients and Methods
2.1. Study
2.2. Statistical Analysis
2.3. Ethical Issues
3. Results
3.1. Patients’ Demographics and Clinical Features
3.2. Treatment Coverture, Viral Suppression, Genotypes, and Level of Awareness
3.3. Other Blood-Borne Virus Co-Infections and Treatments
4. Discussion
5. Conclusions
6. Limitations of the Study
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Beckwith, C.; Castonguay, B.U.; Trezza, C.; Bazerman, L.; Patrick, R.; Cates, A.; Olsen, H.; Kurth, A.; Liu, T.; Peterson, J.; et al. Gender Differences in HIV Care among Criminal Justice-Involved Persons: Baseline Data from the CARE+ Corrections Study. PLoS ONE 2017, 12, e0169078. [Google Scholar] [CrossRef] [PubMed]
- Meyer, J.P.; Cepeda, J.; Faye, S.; Taxman, F.S.; Altice, F.L. Sex-Related Disparities in Criminal Justice and HIV Treatment Outcomes: A Retrospective Cohort Study of HIV-Infected Inmates. Am. J. Public Health 2015, 105, 1901–1910. [Google Scholar] [CrossRef] [PubMed]
- University of Turin. Progetto I.Ri.D.E 2: Una Ricerca Intervento per Definire, Confrontare e Valutare Modelli di Intervento Efficaci e Trasferibili di Riduzione del Danno e dei Rischi di Trasmissione di HIV Nella Popolazione Carceraria. 2016. Available online: https://www.salute.gov.it/imgs/C_17_pagineAree_200_listaFile_itemName_7_file.pdf (accessed on 26 November 2016).
- Fiore, V.; Ranieri, R.; Dell’Isola, S.; Pontali, E.; Barbarini, G.; Prestileo, T.; Marri, D.; Starnini, G.; Sotgiu, G.; Madeddu, G.; et al. Feasibility and efficacy of 8 week Glecaprevir/Pibrentasvir to treat incarcerated viraemic HCV patients: A case-control study. Liver Int. 2020, 41, 271–275. [Google Scholar] [CrossRef] [PubMed]
- Fiore, V.; De Matteis, G.; Ranieri, R.; Saderi, L.; Pontali, E.; Muredda, A.; Ialungo, A.M.; Caruso, R.; Madeddu, G.; Sotgiu, G.; et al. HCV testing and treatment initiation in an Italian prison setting: A step-by-step model to micro-eliminate hepatitis C. Int. J. Drug Policy 2020, 90, 103055. [Google Scholar] [CrossRef] [PubMed]
- Pontali, E.; Fiore, V.; Ialungo, A.M.; Ranieri, R.; Mollaretti, O.; Barbarini, G.; Marri, D.; Prestileo, T.; Dell’Isola, S.; Rastrelli, E.; et al. Treatment with direct-acting antivirals in a multicenter cohort of HCV-infected inmates in Italy. Int. J. Drug Policy 2018, 59, 50–53. [Google Scholar] [CrossRef] [PubMed]
- Rastrelli, E. Gender-specific health in prisons. Ital. J. Gend.-Specif. Med. 2016, 2, 169–175. [Google Scholar]
- Italian Ministry of Justice. Statistics. Available online: https://www.giustizia.it/giustizia/it/ (accessed on 1 October 2022).
- Sagnelli, E.; Starnini, G.; Sagnelli, C.; Monarca, R.; Zumbo, G.; Pontali, E.; Gabbuti, A.; Carbonara, S.; Iardino, R.; Armignacco, O.; et al. Blood born viral infections, sexually transmitted diseases and latent tuberculosis in italian prisons: A preliminary report of a large multicenter study. Eur. Rev. Med. Pharmacol. Sci. 2012, 16, 2142–2146. [Google Scholar] [PubMed]
- Pontali, E.; Ferrari, F. Prevalence of Hepatitis B virus and/or Hepatitis C virus co-infections in prisoners infected with the Human Immunodeficiency Virus. Int. J. Prison. Health 2008, 4, 77–82. [Google Scholar] [CrossRef] [PubMed]
- Monarca, R.; SIMSPe–SIMIT Group; Madeddu, G.; Ranieri, R.; Carbonara, S.; Leo, G.; Sardo, M.; Choroma, F.; Casari, S.; Marri, D.; et al. HIV treatment and care among Italian inmates: A one-month point survey. BMC Infect. Dis. 2015, 15, 562. [Google Scholar] [CrossRef] [PubMed]
- Pontali, E.; Bobbio, N.; Zaccardi, M.; Urciuoli, R. Blood-borne viral co-infections among human immunodeficiency virus-infected inmates. Int. J. Prison. Health 2016, 12, 88–97. [Google Scholar] [CrossRef] [PubMed]
- Sanarico, N.; D’Amato, S.; Bruni, R.; Rovetto, C.; Salvi, E.; Di Zeo, P.; Buttò, S. Correlates of infection and molecular characterization of blood-borne HIV, HCV, and HBV infections in HIV-1 infected inmates in Italy: An observational cross-sectional study. Medicine 2016, 95, e5257. [Google Scholar] [CrossRef] [PubMed]
- Pontali, E.; Ranieri, R.; Rastrelli, E.; Iannece, M.D.; Ialungo, A.M.; Dell’Isola, S.; Liberti, A.; Rosario, P.; Casati, R.; Starnini, G.; et al. Hospital admissions for HIV-infected prisoners in Italy. Int. J. Prison. Health 2017, 13, 105–112. [Google Scholar] [CrossRef] [PubMed]
- Hogben, M.; Leichliter, J. Social determinants and sexually transmitted disease disparities. Sex Transm. Dis. 2008, 35, S13–S18. [Google Scholar] [CrossRef] [PubMed]
- Fiore, V.; Latte, G.; Madeddu, G.; Galleri, G.; Rocchitta, G.; Nuvoli, S.; Calvisi, D.; Bagella, P.; Manetti, R.; Serra, P.A.; et al. Underserved populations and bacterial and protozoal sexually transmitted infections: A lost health-care opportunity. Eur. Rev. Med. Pharmacol. Sci. 2017, 21, 3935–3943. [Google Scholar] [PubMed]
- Fiore, V.; De Vito, A.; Colpani, A.; Manca, V.; Maida, I.; Madeddu, G.; Babudieri, S. Viral Hepatitis C New Microelimination Pathways Objective: Psychiatric Communities HCV Free. Life 2022, 12, 1873. [Google Scholar] [CrossRef] [PubMed]
- Bolcato, M.; Fiore, V.; Casella, F.; Babudieri, S.; Lucania, L.; Di Mizio, G. Health in Prison: Does Penitentiary Medicine in Italy Still Exist? Healthcare 2021, 9, 1511. [Google Scholar] [CrossRef] [PubMed]
- Fiore, V.; Rastrelli, E.; Madeddu, G.; Ranieri, R.; De Vito, A.; Giuliani, R.; Di Mizio, G.; Bolcato, M.; De Matteis, G.; Ialungo, A.M.; et al. HCV spread among female incarcerated population and treatment pathways to viral elimination in Italian prison settings: Clinical perspectives and medico legal aspects. BMC Infect. Dis. 2022, 22, 601. [Google Scholar] [CrossRef] [PubMed]
- Fiore, V.; De Matteis, G.; Pontali, E.; De Vito, A.; Panese, S.; Geremia, N.; Maida, I.; Artioli, S.; Starnini, G.; Madeddu, G.; et al. Quick diagnosis, staging, and treatment of HCV infection among people living in prison: Opinion expert panel. Front. Public Health 2022, 10, 926414. [Google Scholar] [CrossRef] [PubMed]
- Fiore, V.; De Vito, A.; Pontali, E.; Lucania, L.; Madeddu, G.; Babudieri, S. Chronic Viral Hepatitis in the Italian Prison Setting: Prevalence, Outcomes, Literature Needs and Perspectives. Healthcare 2021, 9, 1186. [Google Scholar] [CrossRef] [PubMed]
- Italian Society of Penitentiary Medicine. Statistics. Available online: https://www.sanitapenitenziaria.org/infezione-da-hiv-nella-popolazione-detenuta/ (accessed on 1 October 2022).
Variable | Result |
---|---|
Nationality | |
Italy, n (%) | 50 (58.8) |
Africa, n (%) | 25 (29.4) |
South America | 4 (4.7) |
Slovakia | 2 (2.3) |
Romania | 2 (2.3) |
Czech Republic | 1 (1.2) |
Albania | 1 (1.2) |
Age, mean ± SD | 41.7 ± 8.7 |
Risk factor | |
Drug injection, n (%) | 40 (47) |
Sexual transmission, n (%) | 44 (51.8) |
Blood transfusion | 1 (1.2) |
CD4+ count, median (IQR) | 573 (362–696) |
On HAART, n (%) | 79 (92.9) |
INSTI-based, n (%) | 28 (32.9) |
PI-based, n (%) | 42 (49.4) |
NNRTI-based, n (%) | 7 (8.2) |
Variable | Result |
---|---|
HCV-Ab positive, n (%) Active infection, n (%) | 38 (44.7) 20 (52.2) |
HBV positivity, n (%) HBsAg positive, n (%) OBI, n (%) | 19 (22.3) 3 (15.8) 16 (84.2) |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Rastrelli, E.; Fiore, V.; Ranieri, R.; Pontali, E.; Prestileo, T.; Barbarini, G.; Ialungo, A.M.; Dell’Isola, S.; De Vito, A.; Bolcato, M.; et al. Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network. Viruses 2023, 15, 497. https://doi.org/10.3390/v15020497
Rastrelli E, Fiore V, Ranieri R, Pontali E, Prestileo T, Barbarini G, Ialungo AM, Dell’Isola S, De Vito A, Bolcato M, et al. Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network. Viruses. 2023; 15(2):497. https://doi.org/10.3390/v15020497
Chicago/Turabian StyleRastrelli, Elena, Vito Fiore, Roberto Ranieri, Emanuele Pontali, Tullio Prestileo, Giorgio Barbarini, Anna Maria Ialungo, Serena Dell’Isola, Andrea De Vito, Matteo Bolcato, and et al. 2023. "Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network" Viruses 15, no. 2: 497. https://doi.org/10.3390/v15020497
APA StyleRastrelli, E., Fiore, V., Ranieri, R., Pontali, E., Prestileo, T., Barbarini, G., Ialungo, A. M., Dell’Isola, S., De Vito, A., Bolcato, M., Madeddu, G., Di Mizio, G., Starnini, G., & Babudieri, S., on behalf of ROSE Network. (2023). Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network. Viruses, 15(2), 497. https://doi.org/10.3390/v15020497