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Marine Drugs, Volume 9, Issue 6

2011 June - 16 articles

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Articles (16)

  • Article
  • Open Access
61 Citations
12,287 Views
15 Pages

23 June 2011

In this paper we studied the antioxidant and antiproliferative activities of the heated pepsin hydrolysate from a marine fish half-fin anchovy (HAHp-H). Furthermore, we compared the chemical profiles including the amino acid composition, the browning...

  • Article
  • Open Access
26 Citations
8,307 Views
9 Pages

Zorrimidazolone, a Bioactive Alkaloid from the Non-Indigenous Mediterranean Stolidobranch Polyandrocarpa zorritensis

  • Anna Aiello,
  • Ernesto Fattorusso,
  • Concetta Imperatore,
  • Carlo Irace,
  • Paolo Luciano,
  • Marialuisa Menna,
  • Rita Santamaria and
  • Rocco Vitalone

23 June 2011

Chemical analysis of the Mediterranean ascidian Polyandrocarpa zorritensis (Van Name 1931) resulted in the isolation of a series of molecules including two monoindole alkaloids, 3-indolylglyoxylic acid (3) and its methyl ester (4), 4-hydroxy-3-methox...

  • Article
  • Open Access
31 Citations
10,629 Views
9 Pages

Swinholide J, a Potent Cytotoxin from the Marine Sponge Theonella swinhoei

  • Simona De Marino,
  • Carmen Festa,
  • Maria Valeria D’Auria,
  • Thierry Cresteil,
  • Cecile Debitus and
  • Angela Zampella

22 June 2011

In our ongoing search for new pharmacologically active leads from Solomon organisms, we have examined the sponge Theonella swinhoei. Herein we report the isolation and structure elucidation of swinholide A (1) and one new macrolide, swinholide J (2)....

  • Article
  • Open Access
92 Citations
15,998 Views
14 Pages

17 June 2011

Functional feed supplemented with alternative-economic nutrient sources (protein, carbohydrates, lipids) and probiotics are being considered in shrimp/fish aquaculture production systems as an option to increase yield and profits and to reduce water...

  • Review
  • Open Access
683 Citations
33,235 Views
18 Pages

15 June 2011

For photosynthesis, phototrophic organisms necessarily synthesize not only chlorophylls but also carotenoids. Many kinds of carotenoids are found in algae and, recently, taxonomic studies of algae have been developed. In this review, the relationship...

  • Article
  • Open Access
200 Citations
16,082 Views
18 Pages

14 June 2011

The study was conducted to investigate the promoted immune response to ovalbumin in mice by chitosan nanoparticles (CNP) and its toxicity. CNP did not cause any mortality or side effects when mice were administered subcutaneously twice with a dose of...

  • Review
  • Open Access
696 Citations
33,457 Views
45 Pages

14 June 2011

The marine environment represents a relatively untapped source of functional ingredients that can be applied to various aspects of food processing, storage, and fortification. Moreover, numerous marine-based compounds have been identified as having d...

  • Review
  • Open Access
149 Citations
16,064 Views
14 Pages

Absorption and Metabolism of Xanthophylls

  • Eiichi Kotake-Nara and
  • Akihiko Nagao

10 June 2011

Dietary carotenoids, especially xanthophylls, have attracted significant attention because of their characteristic biological activities, including anti-allergic, anti-cancer, and anti-obese actions. Although no less than forty carotenoids are ingest...

  • Article
  • Open Access
50 Citations
9,662 Views
13 Pages

Bioactive Cembranoids from the Dongsha Atoll Soft Coral Sarcophyton crassocaule

  • Wan-Yu Lin,
  • Yi Lu,
  • Jui-Hsin Su,
  • Zhi-Hong Wen,
  • Chang-Feng Dai,
  • Yao-Haur Kuo and
  • Jyh-Horng Sheu

9 June 2011

Seven new cembranoids, sarcocrassocolides F–L (17), have been isolated from a soft coral Sarcophyton crassocaule. Their structures were determined by extensive spectroscopic analysis. Most new compounds exhibited significant cytotoxic activity again...

  • Article
  • Open Access
16 Citations
10,011 Views
17 Pages

Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis

  • Arturo Soto-Matos,
  • Sergio Szyldergemajn,
  • Sonia Extremera,
  • Bernardo Miguel-Lillo,
  • Vicente Alfaro,
  • Cinthya Coronado,
  • Pilar Lardelli,
  • Elena Roy,
  • Claudia Silvia Corrado and
  • Carmen Kahatt

9 June 2011

Plitidepsin is a cyclic depsipeptide of marine origin in clinical development in cancer patients. Previously, some depsipeptides have been linked to increased cardiac toxicity. Clinical databases were searched for cardiac adverse events (CAEs) that o...

  • Communication
  • Open Access
24 Citations
8,997 Views
10 Pages

8 June 2011

A macrocyclic alkaloid, halicyclamine A, was re-discovered from an Indonesian marine sponge of Haliclona sp. 05A08 as an anti-dormant mycobacterial substance. To clarify action-mechanism of halicyclamine A, halicyclamine A-resistant strains were scre...

  • Article
  • Open Access
138 Citations
14,839 Views
15 Pages

Antioxidant and Antiproliferative Activities of Heterofucans from the Seaweed Sargassum filipendula

  • Leandro Silva Costa,
  • Gabriel Pereira Fidelis,
  • Cinthia Beatrice Silva Telles,
  • Nednaldo Dantas-Santos,
  • Rafael Barros Gomes Camara,
  • Sara Lima Cordeiro,
  • Mariana Santana Santos Pereira Costa,
  • Jailma Almeida-Lima,
  • Raniere Fagundes Melo-Silveira and
  • Hugo Alexandre Oliveira Rocha
  • + 3 authors

7 June 2011

Fucan is a term used to denominate a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups. We obtained five heterofucans from Sargassum filipendula by proteolytic digestion followed by sequential acetone...

  • Article
  • Open Access
221 Citations
22,552 Views
17 Pages

Isolation, Characterization and Biological Evaluation of Jellyfish Collagen for Use in Biomedical Applications

  • Sourour Addad,
  • Jean-Yves Exposito,
  • Clément Faye,
  • Sylvie Ricard-Blum and
  • Claire Lethias

7 June 2011

Fibrillar collagens are the more abundant extracellular proteins. They form a metazoan-specific family, and are highly conserved from sponge to human. Their structural and physiological properties have been successfully used in the food, cosmetic, an...

  • Article
  • Open Access
44 Citations
8,577 Views
8 Pages

27 May 2011

Chemical examination of the Taiwanese soft coral Sinularia triangular led to the isolation of five cembrane-based diterpenoids 15, including two new metabolites, triangulenes A (1) and B (2). The structures of the new metabolites were determined on...

  • Article
  • Open Access
29 Citations
9,357 Views
10 Pages

Discovery of New Eunicellins from an Indonesian Octocoral Cladiella sp.

  • Yung-Husan Chen,
  • Chia-Ying Tai,
  • Yin-Di Su,
  • Yu-Chia Chang,
  • Mei-Chin Lu,
  • Ching-Feng Weng,
  • Jui-Hsin Su,
  • Tsong-Long Hwang,
  • Yang-Chang Wu and
  • Ping-Jyun Sung

26 May 2011

Two new 11-hydroxyeunicellin diterpenoids, cladieunicellin F (1) and (–)-solenopodin C (2), were isolated from an Indonesian octocoral Cladiella sp. The structures of eunicellins 1 and 2 were established by spectroscopic methods, and eunicellin 2 was...

  • Article
  • Open Access
51 Citations
10,722 Views
12 Pages

Antiprotozoal Activities of Organic Extracts from French Marine Seaweeds

  • Catherine Vonthron-Sénécheau,
  • Marcel Kaiser,
  • Isabelle Devambez,
  • Antoine Vastel,
  • Isabelle Mussio and
  • Anne-Marie Rusig

25 May 2011

Marine macrophytes contain a variety of biologically active compounds, some reported to have antiprotozoal activity in vitro. As a part of a screening program to search for new natural antiprotozoals, we screened hydroalcoholic and ethyl acetate extr...

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Mar. Drugs - ISSN 1660-3397