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Article

Exploratory Grouping Along a Shared Oral-Health Burden Continuum in Children and Adolescents: An Age-Stratified Cluster Analysis

by
Narcis Mihaita Bugala
1,
Smaranda-Adelina Bugala
2,*,
Mihaela Jana Țuculină
2,*,
Ancuta Ramona Camen
3,
Alina Nicoleta Capitanescu
4,
Dragos Cadea
5,
Adrian Macovei
5,
Loredana Selaru
6,
Ana Maria Rica
2 and
Dana Maria Albulescu
5
1
Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
2
Department of Endodontics, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
3
Department of Occupational Medicine, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
4
Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
5
Department of Anatomy, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
6
Department of Pediatrics, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
*
Authors to whom correspondence should be addressed.
Medicina 2026, 62(9), 1654; https://doi.org/10.3390/medicina62091654
Submission received: 20 July 2026 / Revised: 24 August 2026 / Accepted: 27 August 2026 / Published: 28 August 2026

Abstract

Background and Objectives: Caries experience, plaque accumulation, gingival inflammation, and periodontal screening findings may coexist as manifestations of a shared oral-health burden. We examined whether these routinely recorded indicators form distinct multivariable profiles or primarily represent ordered levels along a common burden continuum in children and adolescents. Materials and Methods: This secondary exploratory analysis included 638 participants from a multicenter cross-sectional clinical database: 407 aged 6–12 years and 231 aged 13–19 years. Permanent-dentition Decayed, Missing, and Filled Teeth score, Plaque Index, Gingival Index, and Community Periodontal Index were standardized and analyzed separately by age stratum. Unsupervised K-means clustering compared solutions containing two to five groups to summarize participant-level patterns without imposing predefined clinical categories. Hierarchical Ward classification assessed algorithmic concordance; principal component analysis and a composite standardized burden score assessed dimensionality. Sensitivity analyses excluded the periodontal index or treated it as ordinal with Gower-distance partitioning around medoids, and 1000 repeated 80% subsamples assessed sampling stability using the adjusted Rand index. Results: A single principal component explained 91.0% of variance at 6–12 years and 91.8% at 13–19 years, with all four indicators loading strongly on the same dimension. Ordered cluster membership correlated closely with the composite burden score (Spearman ρ = 0.942 and 0.939; both p < 0.001). The retained low-, intermediate-, and high-burden groupings were highly consistent when the periodontal index was excluded or treated as ordinal and under repeated subsampling. In adolescents, a two-group alternative preserved the low- and high-burden extremes while dividing the intermediate group, indicating that the number of groups changes descriptive granularity rather than revealing a separate phenotype. Conclusions: The principal new finding is that four commonly used oral-health indicators converge on one dominant participant-level burden dimension rather than defining distinct clinical phenotypes. This supports an integrated epidemiological description of cumulative oral-health burden while cautioning against interpreting data-driven groups as diagnostic or treatment categories. The numerical group distributions are sample-specific and require external and longitudinal validation before being transferred to other populations or clinical decision-making.
Keywords: dental caries; cluster analysis; dental plaque index; periodontal index; gingivitis; child; adolescent; cross-sectional studies; oral health dental caries; cluster analysis; dental plaque index; periodontal index; gingivitis; child; adolescent; cross-sectional studies; oral health

Share and Cite

MDPI and ACS Style

Bugala, N.M.; Bugala, S.-A.; Țuculină, M.J.; Camen, A.R.; Capitanescu, A.N.; Cadea, D.; Macovei, A.; Selaru, L.; Rica, A.M.; Albulescu, D.M. Exploratory Grouping Along a Shared Oral-Health Burden Continuum in Children and Adolescents: An Age-Stratified Cluster Analysis. Medicina 2026, 62, 1654. https://doi.org/10.3390/medicina62091654

AMA Style

Bugala NM, Bugala S-A, Țuculină MJ, Camen AR, Capitanescu AN, Cadea D, Macovei A, Selaru L, Rica AM, Albulescu DM. Exploratory Grouping Along a Shared Oral-Health Burden Continuum in Children and Adolescents: An Age-Stratified Cluster Analysis. Medicina. 2026; 62(9):1654. https://doi.org/10.3390/medicina62091654

Chicago/Turabian Style

Bugala, Narcis Mihaita, Smaranda-Adelina Bugala, Mihaela Jana Țuculină, Ancuta Ramona Camen, Alina Nicoleta Capitanescu, Dragos Cadea, Adrian Macovei, Loredana Selaru, Ana Maria Rica, and Dana Maria Albulescu. 2026. "Exploratory Grouping Along a Shared Oral-Health Burden Continuum in Children and Adolescents: An Age-Stratified Cluster Analysis" Medicina 62, no. 9: 1654. https://doi.org/10.3390/medicina62091654

APA Style

Bugala, N. M., Bugala, S.-A., Țuculină, M. J., Camen, A. R., Capitanescu, A. N., Cadea, D., Macovei, A., Selaru, L., Rica, A. M., & Albulescu, D. M. (2026). Exploratory Grouping Along a Shared Oral-Health Burden Continuum in Children and Adolescents: An Age-Stratified Cluster Analysis. Medicina, 62(9), 1654. https://doi.org/10.3390/medicina62091654

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