You are currently viewing a new version of our website. To view the old version click .

Current Issues in Molecular Biology, Volume 43, Issue 3

December 2021 - 78 articles

Cover Story: Postmenopausal syndrome refers to cognitive decline and depressive symptoms caused by gradual decrease in female hormones. Radix polygalae has been used for memory boosters and mood stabilizers. In a mouse model of estrogen depletion induced by 4-vinylcyclohexene diepoxide, Radix polygalae improved memory and depressive behaviors. In relation to these behaviors, ChAT, BDNF, and BAG1 expression increased in brain circuits. These results implicate the possible benefit of Radix polygalae in use to prevent conditions such as postmenopausal depression and cognitive decline. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (78)

  • Article
  • Open Access
3 Citations
4,133 Views
12 Pages

1 December 2021

Scutellaria L. (family Lamiaceae) includes approximately 470 species found in most parts of the world and is commonly known as skullcaps. Scutellaria L. is a medicinal herb used as a folk remedy in Korea and East Asia, but it is difficult to identify...

  • Article
  • Open Access
4 Citations
3,696 Views
10 Pages

Gene Expression Studies in Formalin-Fixed Paraffin-Embedded Samples of Cutaneous Cancer: The Need for Reference Genes

  • Omar García-Pérez,
  • Leticia Melgar-Vilaplana,
  • Elizabeth Córdoba-Lanús and
  • Ricardo Fernández-de-Misa

30 November 2021

Formalin-fixed paraffin-embedded (FFPE) tumour samples may provide crucial data regarding biomarkers for neoplasm progression. Analysis of gene expression is frequently used for this purpose. Therefore, mRNA expression needs to be normalized through...

  • Article
  • Open Access
3,509 Views
10 Pages

30 November 2021

For many years, immortalized tumor cell lines have been used as reliable tools to understand the function of oncogenes and tumor suppressor genes. Today, we know that tumors can comprise subclones with common and with subclone-specific genetic altera...

  • Article
  • Open Access
14 Citations
3,757 Views
10 Pages

The Identification of Marker Genes for Predicting the Osteogenic Differentiation Potential of Mesenchymal Stromal Cells

  • Masami Kanawa,
  • Akira Igarashi,
  • Katsumi Fujimoto,
  • Tania Saskianti,
  • Ayumu Nakashima,
  • Yukihito Higashi,
  • Hidemi Kurihara,
  • Yukio Kato and
  • Takeshi Kawamoto

30 November 2021

Mesenchymal stromal cells (MSCs) have the potential to differentiate into a variety of mature cell types and are a promising source of regenerative medicine. The success of regenerative medicine using MSCs strongly depends on their differentiation po...

  • Article
  • Open Access
10 Citations
4,287 Views
11 Pages

29 November 2021

Corneal epithelium maintains visual acuity and is regenerated by the proliferation and differentiation of limbal progenitor cells. Transplantation of human limbal progenitor cells could restore the integrity and functionality of the corneal surface i...

  • Article
  • Open Access
12 Citations
9,052 Views
12 Pages

Evaluation of Microbiome Alterations Following Consumption of BIOHM, a Novel Probiotic

  • Mahmoud A. Ghannoum,
  • Thomas S. McCormick,
  • Mauricio Retuerto,
  • Gurkan Bebek,
  • Susan Cousineau,
  • Lynn Hartman,
  • Charles Barth and
  • Kory Schrom

29 November 2021

Gastrointestinal microbiome dysbiosis may result in harmful effects on the host, including those caused by inflammatory bowel diseases (IBD). The novel probiotic BIOHM, consisting of Bifidobacterium breve, Saccharomyces boulardii, Lactobacillus acido...

  • Article
  • Open Access
2 Citations
3,773 Views
13 Pages

26 November 2021

Mass spawning in fish culture often brings about a marked variance in family size, which can cause a reduction in effective population sizes in seed production for stock enhancement. This study reports an example of combined pedigree information and...

  • Article
  • Open Access
19 Citations
4,739 Views
13 Pages

Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells

  • Yoji Hisamatsu,
  • Hiromi Murata,
  • Hiroaki Tsubokura,
  • Yoshiko Hashimoto,
  • Masaaki Kitada,
  • Susumu Tanaka and
  • Hidetaka Okada

26 November 2021

Cyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue...

  • Article
  • Open Access
7 Citations
4,357 Views
16 Pages

Effect of Metformin and Simvastatin in Inhibiting Proadipogenic Transcription Factors

  • Jelena Jakab,
  • Milorad Zjalić,
  • Štefica Mikšić,
  • Ivan Tušek,
  • Vesna Ćosić,
  • Nikola Volarić,
  • Dario Nakić,
  • Aleksandar Včev and
  • Blaženka Miškić

25 November 2021

Obesity is a multifactorial chronic disease characterized by the excessive accumulation of fat in adipose tissue driven by hypertrophy and hyperplasia of adipocytes through adipogenesis. Adipogenesis plays a key role in the development of obesity and...

  • Article
  • Open Access
7 Citations
15,672 Views
14 Pages

Recombinant Destabilase from Hirudo medicinalis Is Able to Dissolve Human Blood Clots In Vitro

  • Pavel Bobrovsky,
  • Valentin Manuvera,
  • Izolda Baskova,
  • Svetlana Nemirova,
  • Alexandr Medvedev and
  • Vassili Lazarev

20 November 2021

Leeches are amazing animals that can be classified as conditionally poisonous animals since the salivary cocktail they produce is injected directly into the victim, and its components have strictly defined biological purposes, such as preventing bloo...

of 8

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Curr. Issues Mol. Biol. - ISSN 1467-3045