Error in Table
In the original publication [1], there were two mistakes in Table 3 as published. In the chemical structure of ANT-3310 (column 2, row 16) the NO bond was not clearly visible, and in the chemical structure of ANT-2681 (column 2, row 22), an amide functionality, was linked to the thiazole ring in place of an acid one. The corrected Structures of ANT-3310 and ANT-2681 appear below.
ANT-3310
ANT-2681
Error in Schemes
In the original publication, there was a mistake in Scheme 16 as published. In the first three chemical structures of Scheme 16, a BnO ester functionality was reported in the place of an EtO one. The corrected Scheme 16 appears below.
Scheme 16.
Synthesis of ANT-3310 (C6H9 FN2O5S, MW = 240.2), IUPAC name, (2R,5R)-2-fluoro-7-oxo-1,6-diazabicyclo [3.2.1] octan-6-yl hydrogen sulphate.
In the original publication, there was a mistake in Scheme 23 as published. In the final structure of ANT-2681, the PMB protecting group should not have been present. The corrected Scheme 23 appears below.
Scheme 23.
Synthesis of ANT-2681 ANT-2681 (C12H12F2N8O4S2, MW = 434.4), IUPAC name: 5-((4-(2-Carbamimidoylhydrazine-1-carboxamido)-3,5-difluorophenyl) sulphonamide) thiazole-4-carboxamide.
The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.
Reference
- Alfei, S.; Zuccari, G. Recommendations to Synthetize Old and New β-Lactamases Inhibitors: A Review to Encourage Further Production. Pharmaceuticals 2022, 15, 384. [Google Scholar] [CrossRef] [Scilit]
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