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Dimethyl 2-(2,4-Diamino-3-cyano-5H-chromeno[2,3-b]pyridin-5-yl)malonate

N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia
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Academic Editor: Raffaella Mancuso
Molbank 2022, 2022(1), M1308; https://doi.org/10.3390/M1308
Received: 14 December 2021 / Revised: 17 December 2021 / Accepted: 21 December 2021 / Published: 22 December 2021
(This article belongs to the Section Organic Synthesis)
Dimethyl sulfoxide (DMSO) is widely used as a solvent in organic synthesis and in pharmacology because of its low cost, stability, and non-toxicity. Multicomponent reactions are a powerful synthetic tool for the rapid and efficient construction of complicated molecular frameworks. In this communication, the multicomponent transformation of salicylaldehyde, malononitrile dimer, and dimethyl malonate in DMSO at room temperature was carefully investigated to give dimethyl 2-(2,4-diamino-3-cyano-5H-chromeno[2,3-b]pyridin-5-yl)malonate with good yield. The structure of the new compound was established by means of elemental analysis and mass, nuclear magnetic resonance, and infrared spectroscopy. View Full-Text
Keywords: salicylaldehyde; malononitrile dimer; dimethyl malonate; chromeno[2,3-b]pyridines; multicomponent reactions salicylaldehyde; malononitrile dimer; dimethyl malonate; chromeno[2,3-b]pyridines; multicomponent reactions
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MDPI and ACS Style

Ryzhkova, Y.E.; Maslov, O.I.; Elinson, M.N. Dimethyl 2-(2,4-Diamino-3-cyano-5H-chromeno[2,3-b]pyridin-5-yl)malonate. Molbank 2022, 2022, M1308. https://doi.org/10.3390/M1308

AMA Style

Ryzhkova YE, Maslov OI, Elinson MN. Dimethyl 2-(2,4-Diamino-3-cyano-5H-chromeno[2,3-b]pyridin-5-yl)malonate. Molbank. 2022; 2022(1):M1308. https://doi.org/10.3390/M1308

Chicago/Turabian Style

Ryzhkova, Yuliya E., Oleg I. Maslov, and Michail N. Elinson. 2022. "Dimethyl 2-(2,4-Diamino-3-cyano-5H-chromeno[2,3-b]pyridin-5-yl)malonate" Molbank 2022, no. 1: M1308. https://doi.org/10.3390/M1308

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