Skip to Content
  • Retraction
  • Open Access

26 February 2026

1 Page

RETRACTED: Refolo et al. Chlorogenic Acid Improves the Regorafenib Effects in Human Hepatocellular Carcinoma Cells. Int. J. Mol. Sci. 2018, 19, 1518

,
,
,
,
and
Laboratory of Cellular and Molecular Biology, Department of Clinical Pathology, National Institute for Digestive Diseases, IRCCS “Saverio de Bellis”, Via Turi 27, 70013 Castellana Grotte, BA, Italy
*
Authors to whom correspondence should be addressed.
This article belongs to the Section Biochemistry
The Journal retracts the article “Chlorogenic Acid Improves the Regorafenib Effects in Human Hepatocellular Carcinoma Cells” [1] cited above.
Following publication, concerns were brought to the attention of the Editorial Office regarding the integrity of several images presented in this publication [1].
In accordance with the journal’s standard procedures, the Editorial Office and Editorial Board conducted an investigation that confirmed a duplication between sub-panels in Figure 2, as well as a partial duplication of Western blots within Figure 5 and between Figure 5 and Figure 7 in [2], produced by a similar author group, presenting different experimental conditions. The authors fully cooperated with the investigation and indicated that an error had occurred in the collation of the figures. However, as the original images could not be provided for verification, the Editorial Board and the authors were unable to resolve this issue and confirm the reliability of this study. As a Consequence, the Editorial Board has lost confidence in the reliability of the findings and decided to retract this publication [1], as per MDPI’s retraction policy.
This retraction was approved by the Editor-in-Chief of the journal IJMS.
The authors have been informed of this retraction but did not provide a comment on this decision.

References

  1. Refolo, M.G.; Lippolis, C.; Carella, N.; Cavallini, A.; Messa, C.; D’Alessandro, R. RETRACTED: Chlorogenic Acid Improves the Regorafenib Effects in Human Hepatocellular Carcinoma Cells. Int. J. Mol. Sci. 2018, 19, 1518. [Google Scholar] [CrossRef] [Scilit] [PubMed]
  2. Refolo, M.G.; Lotesoriere, C.; Lolli, I.R.; Messa, M.; D’Alessandro, R. Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines. Sci. Rep. 2020, 10, 7162. [Google Scholar] [CrossRef] [Scilit] [PubMed]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Article Metrics

Citations

Article Access Statistics

Multiple requests from the same IP address are counted as one view.