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Mitochondrial Dynamics in Stem Cells and Differentiation

Department of Stem Cell and Regenerative Biotechnology, Konkuk Institute of Technology, Konkuk University, Seoul 05020, Korea
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Int. J. Mol. Sci. 2018, 19(12), 3893; https://doi.org/10.3390/ijms19123893
Received: 31 October 2018 / Revised: 3 December 2018 / Accepted: 4 December 2018 / Published: 5 December 2018
(This article belongs to the Section Molecular Biology)
Mitochondria are highly dynamic organelles that continuously change their shape. Their main function is adenosine triphosphate (ATP) production; however, they are additionally involved in a variety of cellular phenomena, such as apoptosis, cell cycle, proliferation, differentiation, reprogramming, and aging. The change in mitochondrial morphology is closely related to the functionality of mitochondria. Normal mitochondrial dynamics are critical for cellular function, embryonic development, and tissue formation. Thus, defects in proteins involved in mitochondrial dynamics that control mitochondrial fusion and fission can affect cellular differentiation, proliferation, cellular reprogramming, and aging. Here, we review the processes and proteins involved in mitochondrial dynamics and their various associated cellular phenomena. View Full-Text
Keywords: mitochondria; mitochondrial dynamics; fusion; fission; pluripotency; differentiation mitochondria; mitochondrial dynamics; fusion; fission; pluripotency; differentiation
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MDPI and ACS Style

Seo, B.J.; Yoon, S.H.; Do, J.T. Mitochondrial Dynamics in Stem Cells and Differentiation. Int. J. Mol. Sci. 2018, 19, 3893. https://doi.org/10.3390/ijms19123893

AMA Style

Seo BJ, Yoon SH, Do JT. Mitochondrial Dynamics in Stem Cells and Differentiation. International Journal of Molecular Sciences. 2018; 19(12):3893. https://doi.org/10.3390/ijms19123893

Chicago/Turabian Style

Seo, Bong J., Sang H. Yoon, and Jeong T. Do. 2018. "Mitochondrial Dynamics in Stem Cells and Differentiation" International Journal of Molecular Sciences 19, no. 12: 3893. https://doi.org/10.3390/ijms19123893

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