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International Journal of Molecular Sciences, Volume 15, Issue 8

August 2014 - 106 articles

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Articles (106)

  • Article
  • Open Access
31 Citations
7,704 Views
13 Pages

22 August 2014

Radical scavenging activity of anthocyanins is well known, but only a few studies have been conducted by quantum chemical approach. The adaptive neuro-fuzzy inference system (ANFIS) is an effective technique for solving problems with uncertainty. The...

  • Article
  • Open Access
106 Citations
12,435 Views
15 Pages

The Effect of Fiber Bleaching Treatment on the Properties of Poly(lactic acid)/Oil Palm Empty Fruit Bunch Fiber Composites

  • Marwah Rayung,
  • Nor Azowa Ibrahim,
  • Norhazlin Zainuddin,
  • Wan Zuhainis Saad,
  • Nur Inani Abdul Razak and
  • Buong Woei Chieng

22 August 2014

In this work, biodegradable composites from poly(lactic acid) (PLA) and oil palm empty fruit bunch (OPEFB) fiber were prepared by melt blending method. Prior to mixing, the fiber was modified through bleaching treatment using hydrogen peroxide. Bleac...

  • Article
  • Open Access
28 Citations
9,563 Views
10 Pages

Enhancement of Chlorogenic Acid Production in Hairy Roots of Platycodon grandiflorum by Over-Expression of An Arabidopsis thaliana Transcription Factor AtPAP1

  • Pham Anh Tuan,
  • Do Yeon Kwon,
  • Sanghyun Lee,
  • Mariadhas Valan Arasu,
  • Naif Abdullah Al-Dhabi,
  • Nam Il Park and
  • Sang Un Park

22 August 2014

To improve the production of chlorogenic acid (CGA) in hairy roots of Platycodon grandiflorum, we induced over-expression of Arabidopsis thaliana transcription factor production of anthocyanin pigment (AtPAP1) using an Agrobacterium rhizogenes-mediat...

  • Article
  • Open Access
6 Citations
6,905 Views
13 Pages

Affinity Purification of Binding miRNAs for Messenger RNA Fused with a Common Tag

  • Ke Wei,
  • Feng Yan,
  • Hui Xiao,
  • Xiaoxu Yang,
  • Guie Xie,
  • Ye Xiao,
  • Tingting Wang,
  • Yu Xun,
  • Zhaoqin Huang and
  • Shuanglin Xiang
  • + 1 author

22 August 2014

Prediction of microRNA–mRNA interaction typically relies on bioinformatic methods, but these methods only suggest the possibility of microRNA binding and may miss important interactions as well as falsely predict others. A major obstacle to the miRNA...

  • Article
  • Open Access
51 Citations
7,850 Views
20 Pages

Molecular Cloning and Functional Characterization of the Lycopene ε-Cyclase Gene via Virus-Induced Gene Silencing and Its Expression Pattern in Nicotiana tabacum

  • Yanmei Shi,
  • Ran Wang,
  • Zhaopeng Luo,
  • Lifeng Jin,
  • Pingping Liu,
  • Qiansi Chen,
  • Zefeng Li,
  • Feng Li,
  • Chunyang Wei and
  • Jun Yang
  • + 4 authors

22 August 2014

Lycopene ε-cyclase (ε-LCY) is a key enzyme that catalyzes the synthesis of α-branch carotenoids through the cyclization of lycopene. Two cDNA molecules encoding ε-LCY (designated Ntε-LCY1 and Ntε-LCY2) were cloned from Nicotiana tabacum. Ntε-LCY1 a...

  • Article
  • Open Access
20 Citations
6,239 Views
17 Pages

Polymorphism of the Flap Endonuclease 1 Gene in Keratoconus and Fuchs Endothelial Corneal Dystrophy

  • Katarzyna A. Wojcik,
  • Ewelina Synowiec,
  • Piotr Polakowski,
  • Sylwester Głowacki,
  • Justyna Izdebska,
  • Sophie Lloyd,
  • Dieter Galea,
  • Janusz Blasiak,
  • Jerzy Szaflik and
  • Jacek P. Szaflik

22 August 2014

Oxidative stress is implicated in the pathogenesis of many diseases, including serious ocular diseases, keratoconus (KC) and Fuchs endothelial corneal dystrophy (FECD). Flap endonuclease 1 (FEN1) plays an important role in the repair of oxidative DNA...

  • Article
  • Open Access
18 Citations
8,075 Views
16 Pages

22 August 2014

Increased atrial oxidative stress has an important role in inducing and maintaining atrial fibrillation (AF), and the activation of the small GTPase Rac1 contributes to the oxidative stress. We investigated the relationship of Rac1, atrial endothelia...

  • Article
  • Open Access
42 Citations
9,363 Views
16 Pages

ZmCIPK21, A Maize CBL-Interacting Kinase, Enhances Salt Stress Tolerance in Arabidopsis thaliana

  • Xunji Chen,
  • Quansheng Huang,
  • Fan Zhang,
  • Bo Wang,
  • Jianhua Wang and
  • Jun Zheng

22 August 2014

Salt stress represents an increasing threat to crop growth and yield in saline soil. In this study, we identified a maize calcineurin B-like protein-interacting protein kinase (CIPK), ZmCIPK21, which was primarily localized in the cytoplasm and the n...

  • Article
  • Open Access
7 Citations
6,488 Views
13 Pages

Influence of Gradual Elongation to the Patella Tendon Insertion in Rabbits

  • Hirotaka Mutsuzaki,
  • Hiromi Nakajima,
  • Yasuyoshi Wadano,
  • Shintarou Watanabe and
  • Masataka Sakane

22 August 2014

The purpose of this study was to examine the histological changes at the patella tendon (PT) insertion site under gradual elongation in rabbits. Gradual elongation of the PT was performed using external fixation for 4 weeks, with a lengthening speed...

  • Article
  • Open Access
13 Citations
8,731 Views
20 Pages

Multi-Step Pathogenesis and Induction of Local Immune Response by Systemic Candida Albicans Infection in an Intravenous Challenge Mouse Model

  • Voon-Kin Chin,
  • Kuan-Jeang Foong,
  • Abdullah Maha,
  • Basir Rusliza,
  • Mohtarrudin Norhafizah and
  • Pei Pei Chong

22 August 2014

Different murine species differ in their susceptibility to systemic infection with Candida albicans, giving rise to varied host immune responses, and this is compounded by variations in virulence of the different yeast strains used. Hence, this study...

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Int. J. Mol. Sci. - ISSN 1422-0067