Next Article in Journal
Polyphenolic Contents and Antioxidant Potential of Stem Bark Extracts from Jatropha curcas (Linn)
Previous Article in Journal
Flavonoids, Phenolics, and Antioxidant Capacity in the Flower of Eriobotrya japonica Lindl.
Communication

d-(+)-Galactose-Conjugated Single-Walled Carbon Nanotubes as New Chemical Probes for Electrochemical Biosensors for the Cancer Marker Galectin-3

1
Department of Nano System Engineering, Inje University, Gimhae, 612-749, Korea
2
Carbon Valley R & D Division, Jeonju Institute of Machinery and Carbon Composites, Jeonju, 561-844, Korea
3
Nano Carbon Materials Research Group, Korea Electrotechnology Research Institute, Changwon, 641-120, Korea
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2011, 12(5), 2946-2957; https://doi.org/10.3390/ijms12052946
Received: 6 April 2011 / Revised: 22 April 2011 / Accepted: 29 April 2011 / Published: 5 May 2011
(This article belongs to the Section Materials Science)
d-(+)-Galactose-conjugated single-walled carbon nanotubes (SWCNTs) were synthesized for use as biosensors to detect the cancer marker galectin-3. To investigate the binding of galectin-3 to the d-(+)-galactose-conjugated SWCNTs, an electrochemical biosensor was fabricated by using molybdenum electrodes. The binding affinities of the conjugated SWCNTs to galectin-3 were quantified using electrochemical sensitivity measurements based on the differences in resistance together with typical I-V characterization. The electrochemical sensitivity measurements of the d-(+)-galactose-conjugated SWCNTs differed significantly between the samples with and without galectin-3. This indicates that d-(+)-galactose-conjugated SWCNTs are potentially useful electrochemical biosensors for the detection of cancer marker galectin-3. View Full-Text
Keywords: biosensor; cancer marker; galectin-3; galactose; single-walled carbon nanotubes biosensor; cancer marker; galectin-3; galactose; single-walled carbon nanotubes
Show Figures

MDPI and ACS Style

Park, Y.K.; Bold, B.; Lee, W.K.; Jeon, M.H.; An, K.H.; Jeong, S.Y.; Shim, Y.K. d-(+)-Galactose-Conjugated Single-Walled Carbon Nanotubes as New Chemical Probes for Electrochemical Biosensors for the Cancer Marker Galectin-3. Int. J. Mol. Sci. 2011, 12, 2946-2957. https://doi.org/10.3390/ijms12052946

AMA Style

Park YK, Bold B, Lee WK, Jeon MH, An KH, Jeong SY, Shim YK. d-(+)-Galactose-Conjugated Single-Walled Carbon Nanotubes as New Chemical Probes for Electrochemical Biosensors for the Cancer Marker Galectin-3. International Journal of Molecular Sciences. 2011; 12(5):2946-2957. https://doi.org/10.3390/ijms12052946

Chicago/Turabian Style

Park, Young Kum, Bayarmaa Bold, Woo Kyung Lee, Min Hyon Jeon, Kay Hyeok An, Seung Yol Jeong, and Young Key Shim. 2011. "d-(+)-Galactose-Conjugated Single-Walled Carbon Nanotubes as New Chemical Probes for Electrochemical Biosensors for the Cancer Marker Galectin-3" International Journal of Molecular Sciences 12, no. 5: 2946-2957. https://doi.org/10.3390/ijms12052946

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop