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Int. J. Mol. Sci. 2011, 12(5), 2958-2971;

Polyphenolic Contents and Antioxidant Potential of Stem Bark Extracts from Jatropha curcas (Linn)

Drexel University Medical School, St. Peter’s University Hospital, New Brunswick, NJ 08901, USA
Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa
Department of Microbiology and Biochemistry, Ambrose Alli University, Ekpoma, Edo State PMB 14, Nigeria
Department of Microbiology and Biotechnology, Western Delta University, Oghara, Delta State PMB 10, Nigeria
Author to whom correspondence should be addressed.
Received: 7 March 2011 / Revised: 10 April 2011 / Accepted: 27 April 2011 / Published: 5 May 2011
(This article belongs to the Special Issue Antioxidants)
Full-Text   |   PDF [331 KB, uploaded 19 June 2014]


We assessed the polyphenolic contents and antioxidant potential of the aqueous, ethanol and methanol stem bark extracts of Jatropha curcas. The total phenol, flavonoids, flavonols and proanthocyanidin contents of the extracts were evaluated to determine their effect on the antioxidant property of this plant, using standard phytochemical methods. The antioxidant and free radical scavenging activity of ethanol, methanol and aqueous extracts of the plant were also assessed against 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), ferric reducing, nitric oxide (NO), superoxide anion, (O2) and hydrogen peroxide (H2O2) using spectroscopic methods and results were compared with that of butylated hydroxyl toluene (BHT) and ascorbic acid as standards. The concentrations of different classes of phenolic compounds were higher in methanol and ethanol extracts compared to aqueous extracts. There was correlation between total phenol, total flavonoids, total flavonol and total proanthocyanidins (r = 0.996, 0.978, 0.908, and 0.985) respectively. There was correlations between the amount of phenolic compounds and percentage inhibition of DPPH radicals scavenging activity of the extract (r = 0.98). Findings from the present study indicated that J. curcas is a potential source of natural antioxidants and may be a good candidate for pharmaceutical plant based products. View Full-Text
Keywords: Jatropha curcas; antioxidant activity; polyphenolics; free radicals; scavenging capacity Jatropha curcas; antioxidant activity; polyphenolics; free radicals; scavenging capacity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Igbinosa, O.O.; Igbinosa, I.H.; Chigor, V.N.; Uzunuigbe, O.E.; Oyedemi, S.O.; Odjadjare, E.E.; Okoh, A.I.; Igbinosa, E.O. Polyphenolic Contents and Antioxidant Potential of Stem Bark Extracts from Jatropha curcas (Linn). Int. J. Mol. Sci. 2011, 12, 2958-2971.

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