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Open AccessArticle

Impact of Deoxynivalenol on the Intestinal Microflora of Pigs

1
French Agency for Food Safety (AFSSA) – Zoopôle des côtes d’Armor, BP53, 22440 Ploufragan – France
2
French Institute of Agricultural Research (INRA) – UR 66- Unité de Pharmacologie-Toxicologie, 180 chemin de Tournefeuille, 31027 Toulouse cedex 3 – France
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2009, 10(1), 1-17; https://doi.org/10.3390/ijms10010001
Received: 6 November 2008 / Revised: 22 December 2008 / Accepted: 24 December 2008 / Published: 27 December 2008
Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities. View Full-Text
Keywords: Mycotoxin; Deoxynivalenol; pigs; intestinal microflora; growth performance; faeces; anaerobic sulfite-reducing bacteria; CE-SSCP Mycotoxin; Deoxynivalenol; pigs; intestinal microflora; growth performance; faeces; anaerobic sulfite-reducing bacteria; CE-SSCP
MDPI and ACS Style

Waché, Y.J.; Valat, C.; Postollec, G.; Bougeard, S.; Burel, C.; Oswald, I.P.; Fravalo, P. Impact of Deoxynivalenol on the Intestinal Microflora of Pigs. Int. J. Mol. Sci. 2009, 10, 1-17.

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