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International Journal of Molecular Sciences, Volume 10, Issue 1

2009 January - 22 articles

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Articles (22)

  • Article
  • Open Access
10 Citations
13,051 Views
10 Pages

26 January 2009

The Saccharomyces cerevisiae wine yeast strains 71B-1122 and K1-V1116 were used to derive strains that could tolerate and produce higher ethanol yields. Respiratory-deficient mutants resistant to 500 mg/mL lycorine were isolated. Two mutants, 71B-112...

(This article belongs to the Section Biochemistry)
  • Review
  • Open Access
35 Citations
16,257 Views
19 Pages

The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience

  • Irina Dedova,
  • Antony Harding,
  • Donna Sheedy,
  • Therese Garrick,
  • Nina Sundqvist,
  • Clare Hunt,
  • Juliette Gillies and
  • Clive G. Harper

23 January 2009

New developments in molecular neuropathology have evoked increased demands for postmortem human brain tissue. The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leadin...

(This article belongs to the Special Issue Advances in Molecular Neuropathology)
  • Article
  • Open Access
76 Citations
16,193 Views
12 Pages

Synthesis and Evaluation of a Molecularly Imprinted Polymer for 2,4-Dinitrophenol

  • Nor Dyana Zakaria,
  • Nor Azah Yusof,
  • Jelas Haron and
  • Abdul Halim Abdullah

22 January 2009

Molecular imprinted polymers (MIP) are considered one of the most promising selective and novel separation methods for removal phenolic compound in wastewater treatment. MIP are crosslinked polymeric materials that exhibit high binding capacity and s...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
14 Citations
12,753 Views
9 Pages

20 January 2009

Mycobacterium neoaurum is a soil saprophyte and obligate aerobic bacterium. This group of mycobacterium is relatively fast-growing. They form colonies on nutrient agar at 37ºC within 3 – 4 days. In natural soil habitats, bioavailability of iron is li...

(This article belongs to the Section Biochemistry)
  • Review
  • Open Access
219 Citations
21,060 Views
20 Pages

15 January 2009

For the continuous production of electricity with solar heat power plants the storage of heat at a temperature level around 400 °C is essential. High temperature metal hydrides offer high heat storage capacities around this temperature. Based on Mg-c...

(This article belongs to the Section Materials Science)
  • Review
  • Open Access
34 Citations
14,086 Views
19 Pages

13 January 2009

Mitochondria play a key role in the energy metabolism in skeletal muscle. A new concept has emerged suggesting that impaired mitochondrial oxidative capacity in skeletal muscle may be the underlying defect that causes insulin resistance. According to...

(This article belongs to the Special Issue Molecular System Bioenergetics)
  • Article
  • Open Access
19 Citations
14,253 Views
14 Pages

Determination of Mineral Content in Methanolic Safflower (Carthamus tinctorius L.) Seed Extract and Its Effect on Osteoblast Markers

  • Young Seok Lee,
  • Chang Won Choi,
  • Jae Jin Kim,
  • Andy Ganapathi,
  • Rajangam Udayakumar and
  • Sei Chang Kim

12 January 2009

Safflower (Carthamus tinctorius L.) seeds are used as a folk medicine to enhance bone formation or to prevent osteoporosis in Korea. Therefore, the methanolic extract of safflower seeds (MESS) containing high mineral content, such as calcium (Ca), po...

(This article belongs to the Special Issue Natural Compounds for the Treatment and Prevention of Metabolic Diseases)
  • Article
  • Open Access
131 Citations
18,020 Views
11 Pages

Structural Antitumoral Activity Relationships of Synthetic Chalcones

  • Cesar Echeverria,
  • Juan Francisco Santibañez,
  • Oscar Donoso-Tauda,
  • Carlos A. Escobar and
  • Rodrigo Ramirez-Tagle

9 January 2009

Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2’-hydroxychalcones resulted in apoptosis induction and dose-dependent inhibition...

(This article belongs to the Section Biochemistry)
  • Review
  • Open Access
140 Citations
20,726 Views
15 Pages

9 January 2009

The identification of TDP-43 as the major component of the pathologic inclusions in most forms of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis (ALS) resolved a l...

(This article belongs to the Special Issue Advances in Molecular Neuropathology)
  • Review
  • Open Access
29 Citations
35,392 Views
45 Pages

9 January 2009

To what degree could chaos and complexity have organized a Peptide or RNA World of crude yet necessarily integrated protometabolism? How far could such protolife evolve in the absence of a heritable linear digital symbol system that could mutate, ins...

(This article belongs to the Special Issue Origin of Life)
  • Article
  • Open Access
6 Citations
10,087 Views
8 Pages

8 January 2009

Self- and cross-metathesis of fatty acid methyl esters (FAMEs) was investigated using a silica alumina supported Re2O7 catalyst. Although a 3 wt% Re2O7/SiO2-Al2O3/SnBu4 is already active for the metathesis of unsaturated FAMEs, the results have shown...

(This article belongs to the Section Biochemistry)
  • Review
  • Open Access
47 Citations
17,878 Views
29 Pages

Molecular Neuropathology of Gliomas

  • Markus J. Riemenschneider and
  • Guido Reifenberger

7 January 2009

Gliomas are the most common primary human brain tumors. They comprise a heterogeneous group of benign and malignant neoplasms that are histologically classified according to the World Health Organization (WHO) classification of tumors of the nervous...

(This article belongs to the Special Issue Advances in Molecular Neuropathology)
  • Review
  • Open Access
226 Citations
21,836 Views
27 Pages

Trichothecenes in Cereal Grains

  • Nora A. Foroud and
  • François Eudes

6 January 2009

Trichothecenes are sesquiterpenoid mycotoxins associated with fusarium head blight (FHB) of cereals, with worldwide economic and health impacts. While various management strategies have been proposed to reduce the mycotoxin risk, breeding towards FHB...

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)
  • Article
  • Open Access
64 Citations
17,050 Views
10 Pages

Determination of Aflatoxins in Peanut Products in the Northeast Region of São Paulo, Brazil

  • Carlos A. F. Oliveira,
  • Natália B. Gonçalves,
  • Roice E. Rosim and
  • Andrezza M. Fernandes

6 January 2009

The aim of the present study was to determine aflatoxin levels in peanut products traded in the Northeast region of São Paulo, Brazil. To this end, 240 samples of peanut products traded in the cities of Araras, Leme, Pirassununga and Porto Ferreira w...

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)
  • Article
  • Open Access
43 Citations
18,218 Views
14 Pages

Compensatory Growth Induced in Zebrafish Larvae after Pre-Exposure to a Microcystis aeruginosa Natural Bloom Extract Containing Microcystins

  • Issam El Ghazali,
  • Sanaa Saqrane,
  • Antonio Paulo Carvalho,
  • Youness Ouahid,
  • Brahim Oudra,
  • Francisca Fernandez Del Campo and
  • Vitor Vasconcelos

5 January 2009

Early life stage tests with zebrafish (Danio rerio) were used to detect toxic effects of compounds from a Microcystis aeruginosa natural bloom extracton their embryolarval development. We carried out the exposure of developing stages of fish to compl...

(This article belongs to the Special Issue Biotic and Abiotic Stress)
  • Review
  • Open Access
194 Citations
24,935 Views
54 Pages

2 January 2009

Mycotoxins are a group of compounds produced by various fungi and excreted into the matrices on which they grow, often food intended for human consumption or animal feed. The high toxicity and carcinogenicity of these compounds and their ability to c...

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)
  • Article
  • Open Access
63 Citations
17,307 Views
17 Pages

2 January 2009

The SQUAMOSA PROMOTER BINDING PROTEIN–LIKE (SPL) gene family is an SBP-box transcription family in Arabidopsis. While several physiological responses to SPL genes have been reported, their biological role remains elusive. Here, we use a combined anal...

(This article belongs to the Special Issue Algorithms and Molecular Sciences)
  • Article
  • Open Access
112 Citations
15,098 Views
17 Pages

Impact of Deoxynivalenol on the Intestinal Microflora of Pigs

  • Yann J. Waché,
  • Charlotte Valat,
  • Gilbert Postollec,
  • Stephanie Bougeard,
  • Christine Burel,
  • Isabelle P. Oswald and
  • Philippe Fravalo

27 December 2008

Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consu...

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)
  • Article
  • Open Access
15 Citations
9,976 Views
10 Pages

27 December 2008

To perform whole genome scanning for complex trait analysis, we isolated and characterized a total of 21 novel genomic-SSRs and EST-SSRs for yellow perch (Perca flavescens), using the methods of construction of SSR-enrichment libraries and EST databa...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
3 Citations
13,590 Views
9 Pages

Over-expression, Rapid Preparation and Some Properties of C-terminal BARc Region in PICK1

  • Hong Xiao,
  • Yawei Shi,
  • Jingming Yuan,
  • Yuming Huang and
  • Junhua Wang

27 December 2008

A DNA fragment encoding C-terminal BARc region (amino acids 128-416) of rat PICK1 (NP_445912 ) was inserted into a modified vector pMAL-s involving human rhinovirus 3C protease cleavage site to produce a recombinant plasmid, pMAL-s-barc. The construc...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
24 Citations
11,772 Views
13 Pages

27 December 2008

Embryonic midbrain micromass cultures were exposed for five days to ochratoxin A (OTA) at seven concentrations (ranging from 0.16 to 10 μg/mL). Cell viability was assessed in neutral red uptake test (NRU), and differentiation - by immunoenzymatic det...

(This article belongs to the Special Issue Mycotoxins: Mechanisms of Toxicological Activity - Treatment and Prevention)
  • Article
  • Open Access
13 Citations
12,650 Views
12 Pages

Evaluation of Sphingolipids in Wistar Rats Treated to Prolonged and Single Oral Doses of Fumonisin B1

  • Glória M. Direito,
  • Adriana P. Almeida,
  • Simone Aquino,
  • Tatiana Alves dos Reis,
  • Claudia Rodrigues Pozzi and
  • Benedito Corrêa

27 December 2008

The objective of the present study was to evaluate sphingolipid levels (sphingosine-So and sphinganine-Sa) and to compare the Sa/So ratio in liver, serum and urine of Wistar rats after prolonged administration (21 days) of fumonisin B1 (FB1). In para...

(This article belongs to the Section Biochemistry)
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Int. J. Mol. Sci. - ISSN 1422-0067