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Molecules, Volume 26, Issue 15

August-1 2021 - 318 articles

Cover Story: Cyclic trinuclear complexes (CTCs) represent some of the simplest polynuclear metal clusters and have various applications, e.g., exploiting intermolecular M(I)–M(I) interactions, π-acidity and basicity or luminescence. The simplest imidazolate-based scaffold—Au3(Methylimidazolate)3—was first synthesized in 1989 but had not been structurally determined until very recently in 2020. When reinvestigating the synthesis, a new solvatomorph was serendipitously discovered and is reported here. The new solid-state phase comprises metallophilic interactions, which are in general related to emission properties. A combined photophysical, structural, and DFT study is presented to investigate the photophysically active phase and highlights the importance of phase analysis also in the context of molecular compounds. View this paper.
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Articles (318)

  • Article
  • Open Access
1 Citations
4,297 Views
14 Pages

Antiallergic Activity of 6-Deoxy-2-O-methyl-6-(N-hexadecanoyl)amino-l-ascorbic Acid

  • Kaori Miura,
  • Hiroaki Matsuno,
  • Yuji Iwaoka,
  • Hideyuki Ito and
  • Akihiro Tai

3 August 2021

Allergy is an excessive immune response to a specific antigen. Type I allergies, such as hay fever and food allergies, have increased significantly in recent years and have become a worldwide problem. We previously reported that an ascorbic acid deri...

  • Article
  • Open Access
3,532 Views
12 Pages

Detection of 4a,5-dihydropravastatin as Impurity in the Cholesterol Lowering Drug Pravastatin

  • Wibo B. van Scheppingen,
  • Peter P. Lankhorst,
  • Marcus Hans and
  • Marco A. van den Berg

3 August 2021

Dihydro analogues are known byproducts of the fermentative production of statins and cannot be detected with existing pharmacopoeia analysis methods. We detected dihydropravastatin in most commercial formulations of pravastatin with LC-MS, in some ca...

  • Review
  • Open Access
46 Citations
8,166 Views
20 Pages

Downstream Processing of Therapeutic Peptides by Means of Preparative Liquid Chromatography

  • Chiara De Luca,
  • Giulio Lievore,
  • Desiree Bozza,
  • Alessandro Buratti,
  • Alberto Cavazzini,
  • Antonio Ricci,
  • Marco Macis,
  • Walter Cabri,
  • Simona Felletti and
  • Martina Catani

3 August 2021

The market of biomolecules with therapeutic scopes, including peptides, is continuously expanding. The interest towards this class of pharmaceuticals is stimulated by the broad range of bioactivities that peptides can trigger in the human body. The m...

  • Communication
  • Open Access
5 Citations
3,199 Views
13 Pages

3 August 2021

The doubly decarboxylative Michael–type addition of pyridylacetic acid to chromone-3-carboxylic acids or coumarin-3-carboxylic acids has been developed. This protocol has been realized under Brønsted base catalysis, providing biologically interesting...

  • Article
  • Open Access
7 Citations
3,344 Views
15 Pages

Noble Metal Nanoparticles Stabilized by Hyper-Cross-Linked Polystyrene as Effective Catalysts in Hydrogenation of Arenes

  • Elena S. Bakhvalova,
  • Arina O. Pinyukova,
  • Alexey V. Mikheev,
  • Galina N. Demidenko,
  • Mikhail G. Sulman,
  • Alexey V. Bykov,
  • Linda Z. Nikoshvili and
  • Lioubov Kiwi-Minsker

3 August 2021

This work is addressing the arenes’ hydrogenation—the processes of high importance for petrochemical, chemical and pharmaceutical industries. Noble metal (Pd, Pt, Ru) nanoparticles (NPs) stabilized in hyper-cross-linked polystyrene (HPS) were shown t...

  • Article
  • Open Access
91 Citations
5,928 Views
25 Pages

Biochemical and Functional Characterization of Kidney Bean Protein Alcalase-Hydrolysates and Their Preservative Action on Stored Chicken Meat

  • Ahmed M. Saad,
  • Mahmoud Z. Sitohy,
  • Alshaymaa I. Ahmed,
  • Nourhan A. Rabie,
  • Shimaa A. Amin,
  • Salama M. Aboelenin,
  • Mohamed M. Soliman and
  • Mohamed T. El-Saadony

3 August 2021

A new preservation approach is presented in this article to prolong the lifetime of raw chicken meat and enhance its quality at 4 °C via coating with highly soluble kidney bean protein hydrolysate. The hydrolysates of the black, red, and white kidney...

  • Article
  • Open Access
4 Citations
3,147 Views
14 Pages

The Properties of Cu Ions in Zeolites CuY Studied by IR Spectroscopy

  • Jerzy Podobiński,
  • Mariusz Gackowski,
  • Grzegorz Mordarski,
  • Katarzyna Samson,
  • Michał Śliwa,
  • Dorota Rutkowska-Zbik and
  • Jerzy Datka

3 August 2021

The properties of both Cu2+ and Cu+ ions in zeolite CuY were followed with NO and CO as probe molecules. Cu2+ was found to be located in SII, SII*, and SIII sites, whereas Cu+ was found in SII and SII* sites. The fine analysis of the spectra of Cu2+-...

  • Review
  • Open Access
1 Citations
4,052 Views
89 Pages

Recent Advances on O-Ethoxycarbonyl and O-Acyl Protected Cyanohydrins

  • Héctor Manuel Torres Domínguez,
  • Luis Mauricio Hernández Villaverde and
  • Ronan Le Lagadec

3 August 2021

Ethoxycarbonyl cyanohydrins and O-acyl cyanohydrins are examples of O-protected cyanohydrins in which the protecting group presents an electrophilic center, contributing to additional reaction pathways. The first section of this review describes rece...

  • Article
  • Open Access
2 Citations
3,162 Views
14 Pages

3 August 2021

A three-port circulator for optical communication systems comprising a photonic crystal slab made of a magneto-optical material in which an magnetizing element is not required to keep its magnetic domains aligned is suggested for the first time. By m...

  • Essay
  • Open Access
16 Citations
7,474 Views
14 Pages

3 August 2021

The influence of Linus Pauling on the understanding of chemical bonding is critically examined. Pauling deserves credit for presenting a connection between the quantum theoretical description of chemical bonding and Gilbert Lewis’s classical bonding...

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Molecules - ISSN 1420-3049