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Molecules 2018, 23(4), 818; https://doi.org/10.3390/molecules23040818

Extraction and Analysis of Gigantol from Dendrobium officinale with Response Surface Methodology

1
College of Life Science, Anhui Agricultural University, Hefei 230036, China
2
Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Luisella Verotta
Received: 28 February 2018 / Revised: 30 March 2018 / Accepted: 31 March 2018 / Published: 3 April 2018
(This article belongs to the Special Issue Bioactives from Bioprocessing: Sources and Production)
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Abstract

In order to optimize the extraction of gigantol from Dendrobium officinale, the influence of methanol concentration, ultrasonic temperature, and liquid ratio on extraction efficiency was analysed by the response surface analysis method. The results show that the extraction rate reached a maximum when the methanol concentration was 92.98%, the solid-liquid ratio was 27.2 mL/g, and the extraction temperature was 41.41 °C. The content of gigantol of Dendrobium officinale in leaves was significantly higher than that in stems, reaching 4.7942 μg/g. The content of gigantol in Dendrobium huoshanensis Fengdou was significantly higher than that of other species of Fengdou. This experiment has practical significance for improving the utilization rate of Dendrobium officinale, and provides a reference for the study of the pharmacological and biological activity of gigantol. View Full-Text
Keywords: Dendrobium officinale; gigantol; response surface methodology; ultrasonic-assisted extraction Dendrobium officinale; gigantol; response surface methodology; ultrasonic-assisted extraction
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Zheng, S.; Zhu, Y.; Jiao, C.; Shi, M.; Wei, L.; Zhou, Y.; Jin, Q.; Cai, Y. Extraction and Analysis of Gigantol from Dendrobium officinale with Response Surface Methodology. Molecules 2018, 23, 818.

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