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Review

Biomolecule-Functionalized Smart Polydiacetylene for Biomedical and Environmental Sensing

by 1 and 2,*
1
Institute for Ubiquitous Information Technology and Applications (UBITA) & Center for Biotechnology Research in UBITA (CBRU), Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea
2
Department of Bioscience and Biotechnology, Microbial Carbohydrate Resource Bank (MBRC) & Center for Biotechnology Research in UBITA (CBRU), Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea
*
Author to whom correspondence should be addressed.
Molecules 2018, 23(1), 107; https://doi.org/10.3390/molecules23010107
Received: 20 November 2017 / Revised: 22 December 2017 / Accepted: 29 December 2017 / Published: 4 January 2018
(This article belongs to the Section Analytical Chemistry)
Polydiacetylene (PDA) has attracted interest for use as a sensing platform in biomedical, environmental, and chemical engineering applications owing to its capacity for colorimetric and fluorescent transition in response to external stimuli. Many researchers have attempted to develop a tailor-made PDA sensor via conjugation of chemical or biological substances to PDA. Here, we review smart bio-conjugates of PDA with various biomolecules such as carbohydrates, lipids, nucleic acids, and proteins. In addition, materialization and signal amplification strategies to improve handling and sensitivity are described. View Full-Text
Keywords: biomolecules; polydiacetylene; conjugation; sensor biomolecules; polydiacetylene; conjugation; sensor
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MDPI and ACS Style

Cho, E.; Jung, S. Biomolecule-Functionalized Smart Polydiacetylene for Biomedical and Environmental Sensing. Molecules 2018, 23, 107. https://doi.org/10.3390/molecules23010107

AMA Style

Cho E, Jung S. Biomolecule-Functionalized Smart Polydiacetylene for Biomedical and Environmental Sensing. Molecules. 2018; 23(1):107. https://doi.org/10.3390/molecules23010107

Chicago/Turabian Style

Cho, Eunae, and Seunho Jung. 2018. "Biomolecule-Functionalized Smart Polydiacetylene for Biomedical and Environmental Sensing" Molecules 23, no. 1: 107. https://doi.org/10.3390/molecules23010107

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