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Molecules 2017, 22(6), 874;

Isolation of Monoterpene Dihydrochalcones from Piper montealegreanum Yuncker (Piperaceae)

Department of Pharmacy/Post-Graduation Program in Pharmaceutical Sciences, State University of Paraíba, 58429-500 Campina Grande-PB, Brazil
Chemical Science Laboratory, CCT, State University of Fluminense North Darcy Ribeiro, 28013-600 Campo dos Goytacazes-RJ, Brazil
Department of Chemistry, DEQUIM-ICE-Federal University Rural of Rio de Janeiro, CEP 23894-374 Seropédica-RJ, Brazil
Research Institute for Drugs and Medicines, Federal University of Paraíba, CEP 58051-900 João Pessoa-PB, Brazil
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 5 April 2017 / Revised: 18 May 2017 / Accepted: 23 May 2017 / Published: 9 June 2017
(This article belongs to the Section Natural Products Chemistry)
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Four new compounds were isolated from the branches of Piper montealegreanum Yuncker, a shrub found in the Amazon rainforest, including two new dihydrochalcones named claricine (1) and maisine (2), a cinnamic acid derivative 3 and a phenylalkanoid 4, along with a porphyrin identified as the known compound phaeophytin a (5). The structures were established using spectroscopic experiments, including 1D and 2D NMR and HRESIMS experiments, performed on the two monoterpene dihydrochalcones and their monoacetyl derivatives. The structural diversity of these substances is very important for the Piper genus chemotaxonomy. View Full-Text
Keywords: Piper; monoterpene dihydrochalcones; Piper montealegreanum Piper; monoterpene dihydrochalcones; Piper montealegreanum

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Alves, H.S.; Rocha, W.R.V.; Braz-Filho, R.; Chaves, M.C.O. Isolation of Monoterpene Dihydrochalcones from Piper montealegreanum Yuncker (Piperaceae). Molecules 2017, 22, 874.

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