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Open AccessArticle

Indole Alkaloids from the Leaves of Nauclea officinalis

Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen 518060, China
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Author to whom correspondence should be addressed.
Academic Editor: Michael Wink
Molecules 2016, 21(8), 968; https://doi.org/10.3390/molecules21080968
Received: 25 June 2016 / Revised: 18 July 2016 / Accepted: 20 July 2016 / Published: 23 July 2016
(This article belongs to the Special Issue Diversity of Alkaloids)
Three new indole alkaloids, named naucleamide G (1), and nauclealomide B and C (5 and 6), were isolated from the n-BuOH-soluble fraction of an EtOH extract of the leaves of Nauclea officinalis, together with three known alkaloids, paratunamide C (2), paratunamide D (3) and paratunamide A (4). The structures with absolute configurations of the new compounds were identified on the basis of 1D and 2D NMR, HRESIMS, acid hydrolysis and quantum chemical circular dichroism (CD) calculation. According to the structures of isolated indole alkaloids, their plausible biosynthetic pathway was deduced. View Full-Text
Keywords: indole alkaloids; Nauclea officinalis; biosynthetic pathway indole alkaloids; Nauclea officinalis; biosynthetic pathway
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MDPI and ACS Style

Fan, L.; Liao, C.-H.; Kang, Q.-R.; Zheng, K.; Jiang, Y.-C.; He, Z.-D. Indole Alkaloids from the Leaves of Nauclea officinalis. Molecules 2016, 21, 968.

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