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Molecules, Volume 19, Issue 6

June 2014 - 110 articles

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Articles (110)

  • Article
  • Open Access
16 Citations
6,696 Views
11 Pages

Cis-[Cr(C2O4)(pm)(OH2)2]+ Coordination Ion as a Specific Sensing Ion for H2O2 Detection in HT22 Cells

  • Dagmara Jacewicz,
  • Kamila Siedlecka-Kroplewska,
  • Joanna Pranczk,
  • Dariusz Wyrzykowski,
  • Michał Woźniak and
  • Lech Chmurzyński

23 June 2014

The purpose of this study was to examine the application of the coordinated cis-[Cr(C2O4)(pm)(OH)2]+ cation where pm denotes pyridoxamine, as a specific sensing ion for the detection of hydrogen peroxide (H2O2). The proposed method for H2O2 detecti...

  • Article
  • Open Access
38 Citations
7,575 Views
12 Pages

Loddigesiinols G–J: α-Glucosidase Inhibitors from Dendrobium loddigesii

  • Yu Lu,
  • Ming Kuang,
  • Gu-Ping Hu,
  • Rui-Bo Wu,
  • Jun Wang,
  • Lan Liu and
  • Yong-Cheng Lin

23 June 2014

Four new polyphenols, loddigesiinols G–J (compounds 1–4) and a known compound, crepidatuol B (5), were isolated from the stems of Dendrobium loddigesii that have long been used in Traditional Chinese Medicine and have recently been used to treat type...

  • Article
  • Open Access
11 Citations
7,222 Views
15 Pages

Mycelium-Bound Lipase from a Locally Isolated Strain of Geotrichum candidum

  • Joo Ling Loo,
  • Anahita Khoramnia,
  • Oi Ming Lai,
  • Kamariah Long and
  • Hasanah Mohd Ghazali

23 June 2014

Mycelium-bound lipase (MBL), from a locally isolated Geotrichum candidum strain, was produced and characterized as a natural immobilized lipase. A time course study of its lipolytic activity in 1 L liquid broth revealed the maximum MBL activity at 4...

  • Article
  • Open Access
12 Citations
7,514 Views
18 Pages

Evaluation of a Triple-Helical Peptide with Quenched Fluorophores for Optical Imaging of MMP-2 and MMP-9 Proteolytic Activity

  • Xuan Zhang,
  • Jamee Bresee,
  • Philip P. Cheney,
  • Baogang Xu,
  • Manishabrata Bhowmick,
  • Mare Cudic,
  • Gregg B. Fields and
  • Wilson Barry Edwards

23 June 2014

Matrix metalloproteinases (MMP) 2 and 9, the gelatinases, have consistently been associated with tumor progression. The development of gelatinase-specific probes will be critical for identifying in vivo gelatinoic activity to understand the molecular...

  • Review
  • Open Access
72 Citations
16,521 Views
21 Pages

Self-Assembly: From Amphiphiles to Chromophores and Beyond

  • Jonathan P. Hill,
  • Lok Kumar Shrestha,
  • Shinsuke Ishihara,
  • Qingmin Ji and
  • Katsuhiko Ariga

23 June 2014

Self-assembly has been recognised as a ubiquitous aspect of modern chemistry. Our understanding and applications of self-assembly are substantially based on what has been learned from biochemical systems. In this review, we describe various aspects o...

  • Article
  • Open Access
26 Citations
9,185 Views
22 Pages

High-Throughput Assay of Levansucrase Variants in Search of Feasible Catalysts for the Synthesis of Fructooligosaccharides and Levan

  • Karin Mardo,
  • Triinu Visnapuu,
  • Maria Gromkova,
  • Anneli Aasamets,
  • Katrin Viigand,
  • Heiki Vija and
  • Tiina Alamäe

20 June 2014

Bacterial levansucrases polymerize fructose residues of sucrose to β-2,6 linked fructans—fructooligosaccharides (FOS) and levan. While β-2,1-linked FOS are widely recognized as prebiotics, the health-related effects of β-2,6 linked FOS are scarcely s...

  • Article
  • Open Access
14 Citations
7,985 Views
16 Pages

3-Aminothiophene-2-Acylhydrazones: Non-Toxic, Analgesic and Anti-Inflammatory Lead-Candidates

  • Yolanda Karla Cupertino da Silva,
  • Christian Tadeo Moreno Reyes,
  • Gildardo Rivera,
  • Marina Amaral Alves,
  • Eliezer J. Barreiro,
  • Magna Suzana Alexandre Moreira and
  • Lídia Moreira Lima

20 June 2014

Different chemotypes are described as anti-inflammatory. Among them the N-acylhydrazones (NAH) are highlighted by their privileged structure nature, being present in several anti-inflammatory drug-candidates. In this paper a series of functionalized...

  • Article
  • Open Access
26 Citations
7,661 Views
14 Pages

Evidence for the Involvement of Spinal Cord-Inhibitory and Cytokines-Modulatory Mechanisms in the Anti-Hyperalgesic Effect of Hecogenin Acetate, a Steroidal Sapogenin-Acetylated, in Mice

  • Jullyana S.S. Quintans,
  • Rosana S.S. Barreto,
  • Waldecy De Lucca,
  • Cristiane F. Villarreal,
  • Carla M. Kaneto,
  • Milena B.P. Soares,
  • Alexsandro Branco,
  • Jackson R.G.S. Almeida,
  • Alex G. Taranto and
  • Angelo R. Antoniolli
  • + 2 authors

19 June 2014

Hecogenin is a steroidal sapogenin largely drawn from the plants of the genus Agave, commonly known as ‘sisal’, and is one of the important precursors used by the pharmaceutical industry for the synthesis of steroid hormones. Hecogenin acetate (HA) i...

  • Article
  • Open Access
32 Citations
7,581 Views
17 Pages

Xanthenedione Derivatives, New Promising Antioxidant and Acetylcholinesterase Inhibitor Agents

  • Ana M. L. Seca,
  • Stephanie B. Leal,
  • Diana C. G. A. Pinto,
  • Maria Carmo Barreto and
  • Artur M. S. Silva

19 June 2014

Natural and synthetic xanthone derivatives are well-known for their ability to act as antioxidants and/or enzyme inhibitors. This paper aims to present a successful synthetic methodology towards xanthenedione derivatives and the study of their aromat...

  • Review
  • Open Access
22 Citations
9,926 Views
16 Pages

19 June 2014

The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it. This relationship has renewed importance today because diet-induced fatty liver is rel...

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Molecules - ISSN 1420-3049