Innovations in Neurochemical and Electrophysiological Sensing: Materials, Devices, and Techniques
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 1996
Special Issue Editors
2. Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA
3. Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 15213, USA
Interests: electrochemical sensors; neural microelectrodes; glassy carbon; nanomaterials
Special Issues, Collections and Topics in MDPI journals
2. Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USA
3. Fraunhofer USA Center Midwest, East Lansing, MI, USA
Interests: biomedical microelectromechanical systems (BioMEMS); neuroprosthetic devices; microsensors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Understanding brain function requires advanced neural probes capable of monitoring both electrical and chemical signaling across multiple timescales and brain regions. The integration of electrochemical neurotransmitter detection with traditional electrical recording in implantable multielectrode probes has opened new frontiers in neuroscience research. These advancements offer deeper insights into the complex dynamics of neurochemical and electrophysiological processes.
This Special Issue aims to spotlight recent developments in materials, devices, and techniques that have enabled or have the potential to advance dual-mode recordings. The focus is on innovations that not only enhance the functionality of neural probes but also address critical challenges such as sensor fouling and long-term biocompatibility, thereby minimizing brain damage from chronic implantation.
We welcome original research articles, reviews, and mini-reviews that cover a range of topics:
- Advances in the microfabrication processes of neural probes to improve reproducibility, durability, and cost-effectiveness.
- New developments in carbon microelectrodes for dual-mode recordings.
- New detection techniques for longitudinal neurotransmitter detection, such as innovations aimed at the sustained, accurate monitoring of neurotransmitter levels over extended periods.
- Research focused on enhancing the stability and biocompatibility of neural microelectrodes for reliable, long-term recordings of neurochemical and/or electrophysiological signals.
- Development of novel materials and nanocoatings to enhance the sensitivity, selectivity, and stability of neural probes.
- Incorporation of enzyme and aptamer-based recognition methods to improve precision and speficifity.
- Techniques to acquire electrochemical and electrophysiological measurements from the same device (including hardware, software, and devices).
Dr. Elisa Castagnola
Dr. Wen Li
Guest Editors
Manuscript Submission Information
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Keywords
- electrochemical sensors
- neural interfaces
- fast scan cyclic voltammetry
- neurotransmitters
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