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  • Article
  • Open Access
6 Citations
3,173 Views
13 Pages

Validation of a Novel RP-HPLC Technique for Simultaneous Estimation of Lignocaine Hydrochloride and Tibezonium Iodide: Greenness Estimation Using AGREE Penalties

  • Sana Hanif,
  • Muhammad Ali Syed,
  • Ahmad Junaid Rashid,
  • Tareq Nafea Alharby and ,
  • Mohammad M. Algahtani,
  • Muteb Alanazi,
  • Jowaher Alanazi and
  • Rai Muhammad Sarfraz
  • + 3 authors+ 0 author

13 April 2023

Herein, we reported an HPLC method for the simultaneous determination of tibezonium iodide (TBN) and lignocaine hydrochloride (LGN). The method was developed according to the International Conference for Harmonization guidelines (ICH) Q2R1 using Agil...

(This article belongs to the Special Issue Development of Analytical Methods in Food, Biological and Environmental Samples Determination II)
  • Article
  • Open Access
17 Citations
4,608 Views
25 Pages

Evaluating Novel Agarose-Based Buccal Gels Scaffold: Mucoadhesive and Pharmacokinetic Profiling in Healthy Volunteers

  • Muhammad Ali Syed,
  • Ghiyyas Aziz,
  • Muhammad Bilal Jehangir,
  • Tanveer A. Tabish and ,
  • Ameer Fawad Zahoor,
  • Syed Haroon Khalid,
  • Ikram Ullah Khan,
  • Khaled Mohamed Hosny,
  • Waleed Yousof Rizg and
  • Muhammad Irfan
  • + 8 authors+ 3 authors

Agarose (AG) forms hydrocolloid in hot water and possesses a noteworthy gel strength. However, no reasonable scientific work on investigating the mucoadhesive character of AG has been reported. Therefore, the current study was designed to develop AG...

(This article belongs to the Special Issue Mucoadhesive Drug Delivery Systems)