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15 Results Found

  • Communication
  • Open Access
1 Citations
2,483 Views
10 Pages

Retrospective Analysis of Subsolid Nodules’ Frequency Using Chest Computed Tomography Detection in an Outpatient Population

  • Ana Paula Zanardo,
  • Vicente Bohrer Brentano,
  • Rafael Domingos Grando,
  • Rafael Ramos Rambo,
  • Felipe Teixeira Hertz,
  • Luis Carlos Anflor Junior,
  • Jonatas Favero Prietto Dos Santos,
  • Gabriela Schneider Galvao and
  • Cristiano Feijo Andrade

9 August 2023

Introduction: The study was designed to evaluate the frequency of detection and the characteristics of subsolid nodules (SSNs) in outpatients’ chest computed tomography (CT) scans from a private hospital in Southern Brazil. Methods: A retrospec...

  • Review
  • Open Access
16 Citations
5,704 Views
17 Pages

Managing Persistent Subsolid Nodules in Lung Cancer: Education, Decision Making, and Impact of Interval Growth Patterns

  • Yung-Chi Liu,
  • Chia-Hao Liang,
  • Yun-Ju Wu,
  • Chi-Shen Chen,
  • En-Kuei Tang and
  • Fu-Zong Wu

14 August 2023

With the popularization of lung cancer screening, many persistent subsolid nodules (SSNs) have been identified clinically, especially in Asian non-smokers. However, many studies have found that SSNs exhibit heterogeneous growth trends during long-ter...

  • Review
  • Open Access
7 Citations
4,678 Views
11 Pages

What’s New on Quantitative CT Analysis as a Tool to Predict Growth in Persistent Pulmonary Subsolid Nodules? A Literature Review

  • Andrea Borghesi,
  • Silvia Michelini,
  • Salvatore Golemi,
  • Alessandra Scrimieri and
  • Roberto Maroldi

Pulmonary subsolid nodules (SSNs) are observed not infrequently on thin-section chest computed tomography (CT) images. SSNs persisting after a follow-up period of three to six months have a high likelihood of being pre-malignant or malignant lesions....

  • Review
  • Open Access
52 Citations
8,413 Views
15 Pages

Radiomics in Early Lung Cancer Diagnosis: From Diagnosis to Clinical Decision Support and Education

  • Yun-Ju Wu,
  • Fu-Zong Wu,
  • Shu-Ching Yang,
  • En-Kuei Tang and
  • Chia-Hao Liang

Lung cancer is the most frequent cause of cancer-related death around the world. With the recent introduction of low-dose lung computed tomography for lung cancer screening, there has been an increasing number of smoking- and non-smoking-related lung...

  • Article
  • Open Access
6 Citations
4,344 Views
12 Pages

CT-Detected Subsolid Nodules: A Predictor of Lung Cancer Development at Another Location?

  • Anton Schreuder,
  • Mathias Prokop,
  • Ernst T. Scholten,
  • Onno M. Mets,
  • Kaman Chung,
  • Firdaus A. A. Mohamed Hoesein,
  • Colin Jacobs and
  • Cornelia M. Schaefer-Prokop

4 June 2021

The purpose of this case–cohort study was to investigate whether the frequency and computed tomography (CT) features of pulmonary nodules posed a risk for the future development of lung cancer (LC) at a different location. Patients scanned between 20...

  • Article
  • Open Access
1,062 Views
23 Pages

Lung Nodule Malignancy Classification Integrating Deep and Radiomic Features in a Three-Way Attention-Based Fusion Module

  • Sadaf Khademi,
  • Shahin Heidarian,
  • Parnian Afshar,
  • Arash Mohammadi,
  • Abdul Sidiqi,
  • Elsie T. Nguyen,
  • Balaji Ganeshan and
  • Anastasia Oikonomou

13 October 2025

In this study, we propose a novel hybrid framework for assessing the invasiveness of an in-house dataset of 114 pathologically proven lung adenocarcinomas presenting as subsolid nodules on Computed Tomography (CT). Nodules were classified into group...

  • Article
  • Open Access
6 Citations
4,734 Views
10 Pages

Lung Nodules in Melanoma Patients: Morphologic Criteria to Differentiate Non-Metastatic and Metastatic Lesions

  • Simone Alexandra Stadelmann,
  • Christian Blüthgen,
  • Gianluca Milanese,
  • Thi Dan Linh Nguyen-Kim,
  • Julia-Tatjana Maul,
  • Reinhard Dummer,
  • Thomas Frauenfelder and
  • Matthias Eberhard

Lung nodules are frequent findings in chest computed tomography (CT) in patients with metastatic melanoma. In this study, we assessed the frequency and compared morphologic differences of metastases and benign nodules. We retrospectively evaluated 85...

  • Article
  • Open Access
3,145 Views
12 Pages

13 January 2023

This study evaluates ultra-low-dose computed tomography (ULDCT) protocols concerning the detectability of pulmonary nodules. The influence of tube current settings, kernels, strength levels of third-generation iterative reconstruction algorithms, and...

  • Case Report
  • Open Access
2,525 Views
8 Pages

Efficacy of Touch Imprint Cytology in Intraoperative Diagnosis of Invasive Mucinous Adenocarcinoma of the Lung: A Case Report and Literature Review

  • Toshihiko Kato,
  • Yumiko Higuchi,
  • Mei Oshima,
  • Fuki Endo,
  • Fuminori Sato,
  • Shiro Sugihara,
  • Manabu Yamamoto and
  • Yasuo Imai

29 January 2024

A preoperative diagnosis of the peripheral small lung nodule is often difficult, and an intraoperative frozen section diagnosis (FSD) is performed to guide treatment strategy. However, invasive mucinous adenocarcinoma (IMA) is prone to be overlooked...

  • Article
  • Open Access
19 Citations
5,020 Views
19 Pages

A Low-Dose CT-Based Radiomic Model to Improve Characterization and Screening Recall Intervals of Indeterminate Prevalent Pulmonary Nodules

  • Leonardo Rundo,
  • Roberta Eufrasia Ledda,
  • Christian di Noia,
  • Evis Sala,
  • Giancarlo Mauri,
  • Gianluca Milanese,
  • Nicola Sverzellati,
  • Giovanni Apolone,
  • Maria Carla Gilardi and
  • Ugo Pastorino
  • + 2 authors

3 September 2021

Lung cancer (LC) is currently one of the main causes of cancer-related deaths worldwide. Low-dose computed tomography (LDCT) of the chest has been proven effective in secondary prevention (i.e., early detection) of LC by several trials. In this work,...

  • Article
  • Open Access
2,302 Views
13 Pages

Unlocking the Potential of Computed Tomography-Guided Tracers in Pinpointing Lung Lesions during Surgery: A Collaborative Multi-Institutional Journey

  • Rossella Potenza,
  • Marco Andolfi,
  • Andrea Dell’Amore,
  • Marialuisa Lugaresi,
  • Gabriella Roca,
  • Leonardo Valentini,
  • Chiara Catelli,
  • Francesco Buia,
  • Giampiero Dolci and
  • Niccolò Daddi
  • + 6 authors

10 October 2024

Background: Multiple techniques exist for the preoperative localization of small, deeply located solid or subsolid pulmonary nodules to guide limited thoracoscopic resection. This study aims to conduct a multi-institutional comparison of three differ...

  • Article
  • Open Access
2 Citations
1,888 Views
11 Pages

Experimental Examination of Conventional, Semi-Automatic, and Automatic Volumetry Tools for Segmentation of Pulmonary Nodules in a Phantom Study

  • Julian Hlouschek,
  • Britta König,
  • Denise Bos,
  • Alina Santiago,
  • Sebastian Zensen,
  • Johannes Haubold,
  • Christoph Pöttgen,
  • Andreas Herz,
  • Marcel Opitz and
  • Nika Guberina
  • + 5 authors

The aim of this study is to examine the precision of semi-automatic, conventional and automatic volumetry tools for pulmonary nodules in chest CT with phantom N1 LUNGMAN. The phantom is a life-size anatomical chest model with pulmonary nodules repres...

  • Article
  • Open Access
1 Citations
1,483 Views
10 Pages

First 50 Cases with the ION Robotic-Assisted Navigational Bronchoscopy System in Routine Clinical Use in Germany: The Bonn Experience

  • Donatas Zalepugas,
  • Dirk Skowasch,
  • Philipp Feodorovici,
  • Benedetta Bedetti,
  • Philipp Schnorr,
  • Carmen Pizarro,
  • Verena Tischler,
  • Jan Arensmeyer,
  • Daniel Kuetting and
  • Hruy Menghesha
  • + 1 author

31 August 2025

Background: The diagnostic work-up of small peripheral pulmonary nodules (PPNs) is becoming increasingly important, especially in light of the upcoming lung cancer screening programs and recommendations in practice. The systematic clinical introducti...

  • Article
  • Open Access
675 Views
11 Pages

Added Value of SPECT/CT in Radio-Guided Occult Localization (ROLL) of Non-Palpable Pulmonary Nodules Treated with Uniportal Video-Assisted Thoracoscopy

  • Demetrio Aricò,
  • Lucia Motta,
  • Giulia Giacoppo,
  • Michelangelo Bambaci,
  • Paolo Macrì,
  • Stefania Maria,
  • Francesco Barbagallo,
  • Nicola Ricottone,
  • Lorenza Marino and
  • Laura Evangelista
  • + 5 authors

29 July 2025

Background/Objectives: The extensive use of computed tomography (CT) has led to a significant increase in the detection of small and non-palpable pulmonary nodules, necessitating the use of invasive methods for definitive diagnosis. Video-assisted th...

  • Article
  • Open Access
1 Citations
1,654 Views
9 Pages

Clinical Versus Pathological Staging in Patients with Resected Ground Glass Pulmonary Lesions

  • Dan Levy Faber,
  • Abed Agbarya,
  • Andrew Lee,
  • Yael Tsenter,
  • Sonia Schneer,
  • Yulia Robitsky Gelis and
  • Ronen Galili

20 December 2024

Background: A ground glass nodule (GGN) is a radiologically descriptive term for a lung parenchymal area with increased attenuation and preserved bronchial and vascular structures. GGNs are further divided into pure versus subsolid lesions. The diffe...