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11 Results Found

  • Article
  • Open Access
376 Views
15 Pages

Development of a Simplified Geriatric Score-4 (SGS-4) to Predict Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation in Patients Aged over 50

  • Eugenia Accorsi Buttini,
  • Alberto Zucchelli,
  • Paolo Tura,
  • Gianluca Bianco,
  • Daniele Avenoso,
  • Giovanni Campisi,
  • Mirko Farina,
  • Gabriele Magliano,
  • Enrico Morello and
  • Vera Radici
  • + 4 authors

10 October 2025

Background: The Comprehensive Geriatric Assessment (CGA) has proven to be a valuable tool for providing a more comprehensive health evaluation of allogeneic stem cell transplantation (allo-SCT) recipients. Methods: We prospectively developed and test...

  • Article
  • Open Access
1 Citations
618 Views
13 Pages

22 July 2025

Background and Objectives: Immunodeficiency associated with aging comorbidities increases the vulnerability of geriatric patients to sepsis. Early recognition and management of sepsis are essential in this population. This study evaluated the relatio...

  • Review
  • Open Access
5 Citations
2,838 Views
12 Pages

The Role of Geriatric Assessment in the Management of Diffuse Large B-Cell Lymphoma

  • Francesco Merli,
  • Stefano Pozzi,
  • Hillary Catellani,
  • Emiliano Barbieri and
  • Stefano Luminari

14 December 2023

The treatment choice for an older patient with diffuse large B-cell lymphoma (DLBCL) depends on many other factors in addition to age, which alone does not reflect the complexity of the aging process. Functional features and comorbidity incidence dif...

  • Feature Paper
  • Article
  • Open Access
23 Citations
5,279 Views
7 Pages

Relationship between Eating Alone and Poor Appetite Using the Simplified Nutritional Appetite Questionnaire

  • Yurie Mikami,
  • Keiko Motokawa,
  • Maki Shirobe,
  • Ayako Edahiro,
  • Yuki Ohara,
  • Masanori Iwasaki,
  • Misato Hayakawa,
  • Yutaka Watanabe,
  • Hiroki Inagaki and
  • Hunkyung Kim
  • + 3 authors

14 January 2022

One prominent factor associated with malnutrition is poor appetite. In Japan, the number of older adults living alone has increased annually. Those living alone tended to eat alone, which may lead to poor appetite. This study aimed to investigate the...

  • Review
  • Open Access
3 Citations
2,622 Views
13 Pages

Current Treatment Options and the Role of Functional Status Assessment in Classical Hodgkin Lymphoma in Older Adults: A Review

  • Vittorio Ruggero Zilioli,
  • Cristina Muzi,
  • Chiara Pagani,
  • Emanuele Ravano,
  • Erika Meli,
  • Rosa Daffini,
  • Erika Ravelli,
  • Roberto Cairoli and
  • Alessandro Re

28 February 2023

Along with the fact that classical Hodgkin lymphoma (cHL) in older adults is frequently considered biologically different from cHL in younger patients, its most distinctive feature is its dismal clinical outcome due to the decreased effectiveness and...

  • Article
  • Open Access
5 Citations
2,787 Views
12 Pages

A Simplified Screening Tool for the One-Leg Standing Test to Determine the Severity of Locomotive Syndrome

  • Takaomi Kobayashi,
  • Tadatsugu Morimoto,
  • Chisato Shimanoe,
  • Rei Ono,
  • Koji Otani and
  • Masaaki Mawatari

16 May 2023

This study determined the cut-off time for the one-leg standing test (OLST) to simply screen the severity of locomotive syndrome (LS). We conducted this cross-sectional study on 1860 community-dwelling residents (age, 70.5 ± 9.5 years old; mal...

  • Article
  • Open Access
13 Citations
3,685 Views
9 Pages

Functional Constipation and Anorexia in Community-Dwelling Older Adults: Korean Frailty and Aging Cohort Study (KFACS)

  • Eunjin Jeong,
  • Jung A Kim,
  • Byung Sung Kim,
  • Chang Kyun Lee,
  • Miji Kim and
  • Chang Won Won

Anorexia is a relevant geriatric syndrome because it accounts for most malnutrition in older adults. Constipation has been suggested as a risk factor for anorexia. This study aimed to examine the association between anorexia and functional constipati...

  • Article
  • Open Access
3 Citations
2,581 Views
15 Pages

Tools for the Assessment of Risk-Taking Behavior in Older Adults with Mild Dementia: A Cross-Sectional Clinical Study

  • Charline Compagne,
  • Damien Gabriel,
  • Lénaïc Ferrero,
  • Eloi Magnin and
  • Thomas Tannou

Diseases such as Alzheimer’s cause an alteration of cognitive functions, which can lead to increased daily risk-taking in older adults living at home. The assessment of decision-making abilities is primarily based on clinicians’ global an...

  • Article
  • Open Access
1 Citations
1,603 Views
13 Pages

The Association Between Severity of Constipation and Oral Frailty Index-8 in the JUSTICE-TOKYO Study: A Cross-Sectional Study

  • Tsutomu Takeda,
  • Daisuke Asaoka,
  • Hiroyuki Kiko,
  • Takuya Kanazawa,
  • Osamu Nomura,
  • Shotaro Oki,
  • Mariko Hojo,
  • Koji Sugano,
  • Kei Matsuno and
  • Hiroyuki Inoshita
  • + 5 authors

Background/Objectives: Reports on oral frailty as a risk factor for chronic constipation are scarce. In this study, we examined the relationship between Oral Frailty Index-8 (OFI-8) and constipation severity. Methods: This cross-sectional analysis in...

  • Article
  • Open Access
24 Citations
4,535 Views
12 Pages

Comparison of Simplified Creatinine Index and Systemic Inflammatory Markers for Nutritional Evaluation of Hemodialysis Patients

  • Ming-Tsun Tsai,
  • Wei-Cheng Tseng,
  • Shuo-Ming Ou,
  • Kuo-Hua Lee,
  • Chih-Yu Yang and
  • Der-Cherng Tarng

30 May 2021

Protein-energy wasting (PEW) is associated with adverse outcomes in hemodialysis patients. This study compares the simplified creatinine index (SCI) and circulating inflammatory markers as nutritional screening tools for hemodialysis patients. Mainte...

  • Article
  • Open Access
60 Citations
6,313 Views
10 Pages

Inflammation, Appetite and Food Intake in Older Hospitalized Patients

  • Lars Sieske,
  • Gregor Janssen,
  • Nina Babel,
  • Timm Henning Westhoff,
  • Rainer Wirth and
  • Maryam Pourhassan

22 August 2019

The effect of inflammation on appetite and food intake has been rarely studied in humans. In this study, we examined the association of C-reactive protein (CRP), as an inflammatory marker, with appetite and food intake among older hospitalized patien...