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Article

13 Citations

3,637 Views

12 Pages

Comparative Risk Assessment of Three Native Heliotropium Species in Israel

Jakob A. Shimshoni,
Shimon Barel and
Patrick P. J. Mulder

Molecules2021, 26(3), 689;https://doi.org/10.3390/molecules26030689

28 January 2021

Pyrrolizidine alkaloids (PAs) are genotoxic carcinogenic phytotoxins mostly prevalent in the Boraginaceae, Asteraceae and Fabaceae families. Heliotropium species (Boraginaceae) are PA-producing weeds, widely distributed in the Mediterranean region, t...

(This article belongs to the Section Natural Products Chemistry)

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Article

15 Citations

6,000 Views

16 Pages

Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors

Lu Chen,
Qian Zhang,
Ziwei Yi,
Yu Chen and ,
Weihan Xiao,
Dan Su and
Wenbiao Shi
+ 2 authors+ 0 author

Foods2022, 11(19), 2946;https://doi.org/10.3390/foods11192946

21 September 2022

Pyrrolizidine alkaloids (PAs) present distinct toxicity potencies depending on their metabolites and in vivo toxicokinetics. To represent the potency differences of various PAs, the interim relative potency (REP) factors have been derived. However, l...

(This article belongs to the Special Issue Food Contaminant Components: Source, Detection, Toxicity and Removal)

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