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Article

16 Citations

10,305 Views

20 Pages

The Nuclear Dense Fine Speckled (DFS) Immunofluorescence Pattern: Not All Roads Lead to DFS70/LEDGFp75

Evelyn S. Sanchez-Hernandez,
Greisha L. Ortiz-Hernandez,
Pedro T. Ochoa,
Michael Reeves and ,
Nicola Bizzaro,
Luis E. C. Andrade,
Michael Mahler and
Carlos A. Casiano
+ 3 authors+ 0 author

Diagnostics2023, 13(2), 222;https://doi.org/10.3390/diagnostics13020222

7 January 2023

The monospecific dense fine speckled (DFS) immunofluorescence assay (IFA) pattern is considered a potential marker to aid in exclusion of antinuclear antibody (ANA)-associated rheumatic diseases (AARD). This pattern is typically produced by autoantib...

(This article belongs to the Section Clinical Laboratory Medicine)

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Article

3 Citations

7,956 Views

11 Pages

Discriminating between Homogeneous (AC-1) and Dense Fine Speckled (AC-2) Antinuclear Antibody Patterns: Re-Evaluation of Immunofluorescence Imaging

Han-Hua Yu,
Pao-Feng Hsieh,
Szu-Wei Huang,
Tien-Ming Chan and ,
Pao-Lien Tai,
Shih-Ting Yang and
Kuang-Hui Yu
+ 2 authors+ 0 author

Biomedicines2023, 11(11), 3027;https://doi.org/10.3390/biomedicines11113027

11 November 2023

Antinuclear antibodies (ANAs) are essential diagnostic markers in systemic autoimmune rheumatic diseases. Among the 30 ANA patterns, homogeneous (AC-1) and dense fine speckled (AC-2) should be focused on owing to their somewhat indistinct presentatio...

(This article belongs to the Section Immunology and Immunotherapy)

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Review

2 Citations

20,665 Views

13 Pages

The Role of Anti-DFS70 in the Diagnosis of Systemic Autoimmune Rheumatic Diseases

Liudmila Zotova,
Victoria Kotova and
Zakhar Kuznetsov

Biologics2023, 3(4), 342-354;https://doi.org/10.3390/biologics3040019

14 November 2023

The diagnosis of systemic autoimmune rheumatic disease (SARD) or its exclusion is carried out taking into account the results of immunological studies, primarily antinuclear antibodies (ANA) and specific autoantibodies. Often, during ANA analysis via...

(This article belongs to the Section Diagnostics)

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Article

5 Citations

7,941 Views

13 Pages

Mortality in Antinuclear Antibody-Positive Patients with and Without Rheumatologic Immune-Related Disorders: A Large-Scale Population-Based Study

Uria Shani,
Paula David,
Ilana Balassiano Strosberg,
Ohad Regev and ,
Mohamad Yihia,
Niv Ben-Shabat,
Dennis McGonagle,
Orly Weinstein,
Howard Amital and
Abdulla Watad
+ 5 authors+ 0 author

Medicina2025, 61(1), 60;https://doi.org/10.3390/medicina61010060

2 January 2025

Background & Objectives: To explore the potential association between positive ANA serology and all-cause mortality in a large cohort of patients, including those with and without rheumatological conditions and other immune-related diseases. Mate...

(This article belongs to the Special Issue Autoimmune Diseases: Advances and Challenges)

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