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8 Results Found

  • Article
  • Open Access
1 Citations
4,997 Views
11 Pages

Occurrence of Postoperative Delirium and the Use of Different Assessment Tools

  • Andrea Kirfel,
  • Diane Jossen,
  • Jan Menzenbach,
  • Andreas Mayr and
  • Maria Wittmann

(1) Background: Postoperative delirium (POD) poses a high risk of worsening outcomes for patients and is also a burden for hospitals. The leading guidelines recommend standardized POD assessment and prevention. The aim of this subgroup analysis of th...

  • Article
  • Open Access
18 Citations
3,212 Views
12 Pages

Elevated Monocyte Chemoattractant Protein-1 as the Independent Risk Factor of Delirium after Cardiac Surgery. A Prospective Cohort Study

  • Jakub Kaźmierski,
  • Piotr Miler,
  • Agnieszka Pawlak,
  • Hanna Jerczyńska,
  • Joanna Woźniak,
  • Emilia Frankowska,
  • Agnieszka Brzezińska,
  • Katarzyna Woźniak,
  • Michał Krejca and
  • Mirosław Wilczyński

9 April 2021

Background: The pathogenesis of postoperative delirium is largely unknown. The primary objective of this study is to assess whether increased levels of monocyte chemoattractant protein-1 (MCP-1) and high-sensitivity C-reactive protein (hsCRP) are ass...

  • Article
  • Open Access
804 Views
17 Pages

Circulating Brain-Related miRNAs as Predictors of Postoperative Delirium in Cardiac Surgery Patients

  • Karina Nowakowska,
  • Grzegorz Walkiewicz,
  • Emilia Stec-Martyna,
  • Dominika Kulczycka-Wojdala,
  • Emilia Frankowska,
  • Piotr Miler,
  • Agnieszka Pawlak,
  • Katarzyna Woźniak,
  • Michał Krejca and
  • Mirosław Wilczyński
  • + 1 author

17 September 2025

Delirium is a neuropsychiatric syndrome that is pathophysiologically related to both mental (dementia, depression) and physical illness. Its occurrence results in a poor prognosis. This study investigates whether specific miRNAs (miR-9-3p, miR-34c-5p...

  • Systematic Review
  • Open Access
4 Citations
7,610 Views
16 Pages

The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review

  • Sarai Zaher-Sánchez,
  • Pedro José Satústegui-Dordá,
  • Enrique Ramón-Arbués,
  • Jose Angel Santos-Sánchez,
  • Juan José Aguilón-Leiva,
  • Sofía Pérez-Calahorra,
  • Raúl Juárez-Vela,
  • Teresa Sufrate-Sorzano,
  • Beatriz Angulo-Nalda and
  • María Elena Garrote-Cámara
  • + 2 authors

15 October 2024

Background: Delirium or an acute confusional state (ACS) is characterised as being a frequent and complex hospital complication in older adult patients, which can affect their level of independence and increase patient morbidity and mortality. Critic...

  • Article
  • Open Access
574 Views
12 Pages

Comparison of DeltaScan® and CAM-ICU for the Assessment of Postoperative Delirium in Patients Undergoing Cardiac Surgery and Cardiac Interventions: A Prospective Observational Pilot Study

  • Astrid Bergmann,
  • Janis Fliegenschmidt,
  • Silvia Ruggeri,
  • Nikolai Hulde,
  • Catharina Middeke,
  • Claudia Bunge,
  • Maria Preising,
  • Carsten Hermes and
  • Vera von Dossow

21 October 2025

Background: Postoperative delirium is frequent among elderly patients and often presents after major surgery or intervention. Validated screening tools should be routinely used to recognise this psychopathological syndrome. Delirium might be associat...

  • Article
  • Open Access
9 Citations
6,162 Views
20 Pages

Postoperative Delirium and Cognitive Dysfunction After Cardiac Surgery: The Role of Inflammation and Clinical Risk Factors

  • Raluca-Elisabeta Staicu,
  • Corina Vernic,
  • Sebastian Ciurescu,
  • Ana Lascu,
  • Oana-Maria Aburel,
  • Petru Deutsch and
  • Elena Cecilia Rosca

Background/Objectives: Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are prevalent neurological complications following cardiac surgery, significantly affecting patient recovery and long-term outcomes, including increase...

  • Article
  • Open Access
18 Citations
4,494 Views
10 Pages

The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients

  • Ana-Maria Cotae,
  • Mirela Ţigliş,
  • Cristian Cobilinschi,
  • Alexandru Emil Băetu,
  • Diana Maria Iacob and
  • Ioana Marina Grinţescu

23 April 2021

Background and Objectives: Patients with traumatic injuries have often been excluded from studies that have attempted to pinpoint modifiable factors to predict the transient disturbance of the cognitive function in the postoperative settings. Anesthe...

  • Article
  • Open Access
8 Citations
5,256 Views
11 Pages

Morbidity and Mortality in Patients over 90 Years of Age Following Posterior Stabilization for Acute Traumatic Odontoid Type II Fractures: A Retrospective Study with a Mean Follow-Up of Three Years

  • Mohammed Issa,
  • Karl L. Kiening,
  • Andreas W. Unterberg,
  • Moritz Scherer,
  • Alexander Younsi,
  • Stepan Fedorko,
  • Rod J. Oskouian,
  • Jens R. Chapman and
  • Basem Ishak

24 August 2021

Odontoid type II fractures represent the most common cervical spine injuries in the elderly. The decision for surgical treatment in very elderly patients is still controversial. The aim of this study was to assess morbidity and mortality in patients...