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Article

9 Citations

6,302 Views

12 Pages

In Vitro Antileishmanial and Antischistosomal Activities of Anemonin Isolated from the Fresh Leaves of Ranunculus multifidus Forsk

Betelhem Sirak,
Kaleab Asres,
Asrat Hailu,
Mthandazo Dube,
Norbert Arnold,
Cecile Häberli,
Jennifer Keiser and
Peter Imming

Molecules2021, 26(24), 7473;https://doi.org/10.3390/molecules26247473

10 December 2021

Leishmaniasis and schistosomiasis are neglected tropical diseases (NTDs) infecting the world’s poorest populations. Effectiveness of the current antileishmanial and antischistosomal therapies are significantly declining, which calls for an urge...

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Article

13 Citations

6,386 Views

16 Pages

In Vivo Antimalarial Activity of Leaf Extracts and a Major Compound Isolated from Ranunculus multifidus Forsk

Betelhem Sirak,
Lea Mann,
Adrian Richter,
Kaleab Asres and
Peter Imming

Molecules2021, 26(20), 6179;https://doi.org/10.3390/molecules26206179

13 October 2021

The leaves of Ranunculus multifidus Forsk. are traditionally used for the treatment of malaria in several African countries. In the present study, 80% methanol (RM-M) and hydrodistilled (RM-H) extracts of fresh leaves from R. multifidus and its major...

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Article

4 Citations

2,771 Views

26 Pages

Potential Benefits of Dietary Plant Compounds on Normal and Tumor Brain Cells in Humans: In Silico and In Vitro Approaches

Lucia Camelia Pirvu,
Georgeta Neagu,
Adrian Albulescu,
Amalia Stefaniu and
Lucia Pintilie

Int. J. Mol. Sci.2023, 24(8), 7404;https://doi.org/10.3390/ijms24087404

17 April 2023

Neuroblastoma can be accessed with compounds of larger sizes and wider polarities, which do not usually cross the blood–brain barrier. Clinical data indicate cases of spontaneous regression of neuroblastoma, suggesting a reversible point in the...

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