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3 Results Found

  • Review
  • Open Access
3 Citations
3,147 Views
10 Pages

HUNK Gene Alterations in Breast Cancer

  • Nicole Ramos-Solis,
  • Tinslee Dilday,
  • Alex E. Kritikos and
  • Elizabeth S. Yeh

29 November 2022

Hormonally upregulated neu-associated kinase (HUNK) is a serine/threonine (S/T) protein kinase related to the adenosine monophosphate-activated protein kinase (AMPK) family of kinases. HUNK was originally discovered using a screen to identify kinases...

(This article belongs to the Section Cancer Biology and Oncology)
  • Article
  • Open Access
15 Citations
6,072 Views
11 Pages

HUNK Phosphorylates Rubicon to Support Autophagy

  • Joelle N. Zambrano,
  • Scott T. Eblen,
  • Melissa Abt,
  • J. Matthew Rhett and ,
  • Robin Muise-Helmericks and
  • Elizabeth S. Yeh
  • + 1 author+ 0 author

19 November 2019

Background: Autophagy is a catabolic cellular recycling pathway that is essential for maintaining intracellular homeostasis. Autophagosome formation is achieved via the coordination of the Beclin-1 protein complex. Rubicon is a Beclin-1 associated pr...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
5 Citations
4,893 Views
38 Pages

28 March 2024

Software evolution is driven by changes made during software development and maintenance. While source control systems effectively manage these changes at the commit level, the intent behind them are often inadequately documented, making understandin...