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Review

35 Citations

16,040 Views

17 Pages

Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure

Barbara Ficial,
Francesco Vasques,
Joe Zhang,
Stephen Whebell,
Michael Slattery,
Tomas Lamas,
Kathleen Daly,
Nicola Agnew and
Luigi Camporota

Membranes2021, 11(3), 225;https://doi.org/10.3390/membranes11030225

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22 March 2021

Extracorporeal life support (ECLS) for severe respiratory failure has seen an exponential growth in recent years. Extracorporeal membrane oxygenation (ECMO) and extracorporeal CO2 removal (ECCO2R) represent two modalities that can provide full or par...

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Review

2 Citations

4,832 Views

16 Pages

Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal

Tomás Lamas,
Susana M. Fernandes,
Francesco Vasques,
Christian Karagiannidis,
Luigi Camporota and
Nicholas Barrett

J. Clin. Med.2025, 14(1), 12;https://doi.org/10.3390/jcm14010012

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24 December 2024

Extracorporeal carbon dioxide removal (ECCO2R) is an emerging technique designed to reduce carbon dioxide (CO2) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing. Unlike high-flow extracorporeal me...

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Case Report

3 Citations

2,807 Views

10 Pages

Ultraprotective Ventilation via ECCO2R in Three Patients Presenting an Air Leak: Is ECCO2R Effective?

Carolina Ferrer Gómez,
Tania Gabaldón and
Javier Hernández Laforet

J. Pers. Med.2023, 13(7), 1081;https://doi.org/10.3390/jpm13071081

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29 June 2023

Extracorporeal CO2 removal (ECCO2R) is a therapeutic approach that allows protective ventilation in acute respiratory failure by preventing hypercapnia and subsequent acidosis. The main indications for ECCO2R in acute respiratory failure are COPD (ch...

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Article

1 Citations

2,746 Views

19 Pages

A Wearable Extracorporeal CO₂ Removal System with a Closed-Loop Feedback

Andrew Zhang,
Brian J. Haimowitz,
Kartik Tharwani,
Alvaro Rojas-Peña,
Robert H. Bartlett and
Joseph A. Potkay

Bioengineering2024, 11(10), 969;https://doi.org/10.3390/bioengineering11100969

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27 September 2024

Extracorporeal Carbon Dioxide Removal (ECCO2R) systems support patients with severe respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes, but these procedures are limited by the complexity and size of the extracorp...

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Review

8 Citations

6,346 Views

16 Pages

Extracorporeal Carbon Dioxide Removal: From Pathophysiology to Clinical Applications; Focus on Combined Continuous Renal Replacement Therapy

Francesca Cappadona,
Elisa Costa,
Laura Mallia,
Filippo Sangregorio,
Lorenzo Nescis,
Valentina Zanetti,
Elisa Russo,
Stefania Bianzina,
Francesca Viazzi and
Pasquale Esposito

Biomedicines2023, 11(1), 142;https://doi.org/10.3390/biomedicines11010142

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5 January 2023

Lung-protective ventilation (LPV) with low tidal volumes can significantly increase the survival of patients with acute respiratory distress syndrome (ARDS) by limiting ventilator-induced lung injuries. However, one of the main concerns regarding the...

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Article

2 Citations

3,133 Views

11 Pages

Safety and Effectiveness of Carbon Dioxide Removal CO2RESET Device in Critically Ill Patients

Fabio Silvio Taccone,
Simone Rinaldi,
Filippo Annoni,
Leda Nobile,
Matteo Di Nardo,
Jessica Maccieri,
Anna Aliberti,
Maximilan Valentin Malfertheiner,
Andrea Marudi and
Mirko Belliato
+ 1 author

Membranes2023, 13(7), 686;https://doi.org/10.3390/membranes13070686

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24 July 2023

Background: In this retrospective study, we report the effectiveness and safety of a dedicated extracorporeal carbon dioxide removal (ECCO2R) device in critically ill patients. Methods: Adult patients on mechanical ventilation due to acute respirator...

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Article

4 Citations

5,192 Views

9 Pages

Evaluation of a New Extracorporeal CO₂ Removal Device in an Experimental Setting

Matteo Di Nardo,
Filippo Annoni,
Fuhong Su,
Mirko Belliato,
Roberto Lorusso,
Lars Mikael Broman,
Maximilian Malfertheiner,
Jacques Creteur and
Fabio Silvio Taccone

Membranes2021, 11(1), 8;https://doi.org/10.3390/membranes11010008

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23 December 2020

Background: Ultra-protective lung ventilation in acute respiratory distress syndrome or early weaning and/or avoidance of mechanical ventilation in decompensated chronic obstructive pulmonary disease may be facilitated by the use of extracorporeal CO...

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Article

2 Citations

3,262 Views

18 Pages

Alkaline Liquid Ventilation of the Membrane Lung for Extracorporeal Carbon Dioxide Removal (ECCO₂R): In Vitro Study

Luigi Vivona,
Michele Battistin,
Eleonora Carlesso,
Thomas Langer,
Carlo Valsecchi,
Sebastiano Maria Colombo,
Serena Todaro,
Stefano Gatti,
Gaetano Florio and
Alberto Zanella
+ 2 authors

Membranes2021, 11(7), 464;https://doi.org/10.3390/membranes11070464

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22 June 2021

Extracorporeal carbon dioxide removal (ECCO2R) is a promising strategy to manage acute respiratory failure. We hypothesized that ECCO2R could be enhanced by ventilating the membrane lung with a sodium hydroxide (NaOH) solution with high CO2 absorbing...

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Article

3 Citations

3,421 Views

12 Pages

Comparison of Circular and Parallel-Plated Membrane Lungs for Extracorporeal Carbon Dioxide Elimination

Leonie S. Schwärzel,
Anna M. Jungmann,
Nicole Schmoll,
Stefan Caspari,
Frederik Seiler,
Ralf M. Muellenbach,
Moritz Bewarder,
Quoc Thai Dinh,
Robert Bals and
Albert J. Omlor
+ 1 author

Membranes2021, 11(6), 398;https://doi.org/10.3390/membranes11060398

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27 May 2021

Extracorporeal carbon dioxide removal (ECCO2R) is an important technique to treat critical lung diseases such as exacerbated chronic obstructive pulmonary disease (COPD) and mild or moderate acute respiratory distress syndrome (ARDS). This study appl...

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Article

13 Citations

4,949 Views

18 Pages

Development of a CO₂ Sensor for Extracorporeal Life Support Applications

Michele Bellancini,
Laura Cercenelli,
Stefano Severi,
Guido Comai and
Emanuela Marcelli

Sensors2020, 20(13), 3613;https://doi.org/10.3390/s20133613

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27 June 2020

Measurement of carbon dioxide (CO2) in medical applications is a well-established method for monitoring patient’s pulmonary function in a noninvasive way widely used in emergency, intensive care, and during anesthesia. Even in extracorporeal-li...

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10 Results Found

Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure

Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal

Ultraprotective Ventilation via ECCO2R in Three Patients Presenting an Air Leak: Is ECCO2R Effective?

A Wearable Extracorporeal CO2 Removal System with a Closed-Loop Feedback

Extracorporeal Carbon Dioxide Removal: From Pathophysiology to Clinical Applications; Focus on Combined Continuous Renal Replacement Therapy

Safety and Effectiveness of Carbon Dioxide Removal CO2RESET Device in Critically Ill Patients

Evaluation of a New Extracorporeal CO2 Removal Device in an Experimental Setting

Alkaline Liquid Ventilation of the Membrane Lung for Extracorporeal Carbon Dioxide Removal (ECCO2R): In Vitro Study

Comparison of Circular and Parallel-Plated Membrane Lungs for Extracorporeal Carbon Dioxide Elimination

Development of a CO2 Sensor for Extracorporeal Life Support Applications

A Wearable Extracorporeal CO₂ Removal System with a Closed-Loop Feedback

Evaluation of a New Extracorporeal CO₂ Removal Device in an Experimental Setting

Alkaline Liquid Ventilation of the Membrane Lung for Extracorporeal Carbon Dioxide Removal (ECCO₂R): In Vitro Study

Development of a CO₂ Sensor for Extracorporeal Life Support Applications