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Target Design of Novel Histone Deacetylase 6 Selective Inhibitors with 2-Mercaptoquinazolinone as the Cap Moiety

  • Hue Thi Buu Bui,
  • Phuong Hong Nguyen,
  • Quan Minh Pham,
  • Hoa Phuong Tran and ,
  • De Quang Tran,
  • Hosun Jung,
  • Quang Vinh Hong,
  • Quoc Cuong Nguyen,
  • Quy Phu Nguyen and
  • Su-Geun Yang
  • + 6 authors+ 1 author
Molecules2022, 27(7), 2204;https://doi.org/10.3390/molecules27072204

28 March 2022

Epigenetic alterations found in all human cancers are promising targets for anticancer therapy. In this sense, histone deacetylase inhibitors (HDACIs) are interesting anticancer agents that play an important role in the epigenetic regulation of cance...

(This article belongs to the Section Medicinal Chemistry)
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