Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Enveloped and Non-Enveloped Virus Assembly submission deadline 30 Nov 2025 | Viewed by 220 | Submission Open
Keywords: virus assembly; viral host factors; virus methodology; virus egress; membrane remodeling; cellular imaging; virus budding and release; protein-protein interactions; genome packaging; viral capsid; assembly inhibitors
(This special issue belongs to the Section Human Virology and Viral Diseases)
Cellular Mechanisms Regulating HIV Replication, 2nd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 135 | Submission Open
Keywords: HIV-1; HIV-1 replication; host factors
(This special issue belongs to the Section Human Virology and Viral Diseases)
Functional Structures in RNA Viruses
edited by Riccardo Delli Ponti, , and Laura Broglia
submission deadline 30 Nov 2025 | Viewed by 72 | Submission Open
Keywords: RNA secondary structure; RNA viruses; machine learning; SHAPE; protein– RNA interactions
(This special issue belongs to the Section General Virology)
Virology Research in South Africa—from a Great Legacy to an Optimistic Future submission deadline 1 Dec 2025 | 9 articles | Viewed by 27936 | Submission Open
Keywords: SARS-CoV-2; other respiratory viruses; vaccines; HIV; antiviral resistance; zoonotic viruses; hepatitis viruses; enteric viruses; novel viruses/virus discovery
(This special issue belongs to the Section General Virology)
Structure-Based Antiviral Drugs and Vaccine Design
edited by and
submission deadline 15 Dec 2025 | 3 articles | Viewed by 3147 | Submission Open
Keywords: antiviral; structure based; AI-powered; drug design; vaccine design
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Bioinformatics and Computational Approaches in Viral Genomics and Evolution 2025
edited by Camila Malta Romano, Mariana Severo Ramundo and Nilson Coimbra
submission deadline 16 Dec 2025 | 4 articles | Viewed by 3479 | Submission Open
Keywords: bioinformatics tools; genomic surveillance; viral evolution; computational genomics; host-pathogen interactions
(This special issue belongs to the Section General Virology)
Diversity and Coinfections of Plant or Fungal Viruses, 3rd Edition submission deadline 20 Dec 2025 | 4 articles | Viewed by 6168 | Submission Open
Keywords: diagnosis; surveillance; molecular mechanism; viroid; subviral agents; mycoviruses; biological control; pesticide resistance; antiviral defense mechanism; population genetics; recombination; gene expressions; host range
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Swine Viruses: Immunology and Vaccinology
edited by and
submission deadline 20 Dec 2025 | 1 articles | Viewed by 808 | Submission Open
Keywords: swine virology; swine immunology; vaccine development; vaccinology; viral pathogenesis; vaccine design; disease prevention; swine health
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Virology in Italy 2025—9th National Congress of the Italian Society for Virology submission deadline 20 Dec 2025 | Viewed by 255 | Submission Open
Keywords: Italy; emerging viruses; viral subversion of host cell processes; viruses of microbes; antivirals; vaccines; emerging methods in virology; RNA in virus infection; plant viruses; antiviral innate immunity; animal viruses; mycoviruses
(This special issue belongs to the Section General Virology)
Understanding the Oncogenesis of Human Herpesviruses through Their Critical Comparisons
edited by Ya-Fang Chiu and Bill Sugden
submission deadline 30 Dec 2025 | 3 articles | Viewed by 7027 | Submission Open
(This special issue belongs to the Section Human Virology and Viral Diseases)
RSV Epidemiological Surveillance: 2nd Edition
edited by Emanuele Castagno and Irene Raffaldi
submission deadline 30 Dec 2025 | 4 articles | Viewed by 5007 | Submission Open
Keywords: respiratory syncytial virus (RSV); epidemiological surveillance; bronchiolitis; children; newborns; infants
(This special issue belongs to the Section Human Virology and Viral Diseases)
Immune Mechanisms Against Respiratory Viral Pathogens
edited by Telugu Akula Narasaraju and Sunil More
submission deadline 30 Dec 2025 | Viewed by 89 | Submission Open
Keywords: respiratory viral infections; innate and adaptive immunity; host– pathogen interactions; inflammatory response; therapeutic interventions
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
HIV Reservoirs, Latency, and the Factors Responsible
edited by Yuyang Tang and
submission deadline 31 Dec 2025 | 4 articles | Viewed by 19930 | Submission Open
Keywords: HIV; HIV latency; HIV persistence; HIV eradication; HIV cure; HIV vaccine
(This special issue belongs to the Section Human Virology and Viral Diseases)
Microscopy Methods for Virus Research
edited by Krishanu Ray
submission deadline 31 Dec 2025 | 7 articles | Viewed by 16961 | Submission Open
Keywords: viruses; fluorescence imaging; single-molecule imaging; super-resolution imaging; intra-vital imaging; electron microscopy; Cryo-EM; Cryo-ET
(This special issue belongs to the Section General Virology)
Viral Infections and Immune Dysregulation 2024–2025 submission deadline 31 Dec 2025 | 6 articles | Viewed by 15617 | Submission Open
Keywords: immune responses; immune dysregulation; autoimmunity; viral infections; immunomodulation
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Controlling Zoonotic Viral Diseases from One Health Perspective 2025
edited by and Erika Schwarz-Collins
submission deadline 31 Dec 2025 | 5 articles | Viewed by 13891 | Submission Open
Keywords: one health; viral zoonoses; control; vaccine; surveillance; epidemiology
(This special issue belongs to the Section Animal Viruses)
H5N1 Influenza Viruses
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 8906 | Submission Open
Keywords: H5N1; avian influenza; genetic diversity; immune response; vaccines and antiviral therapies
(This special issue belongs to the Section Animal Viruses)
EBV and Disease: New Perspectives in the Post COVID-19 Era
edited by and Dengke Li
submission deadline 31 Dec 2025 | 6 articles | Viewed by 8089 | Submission Open
Keywords: EBV; reactivation and immune dysregulation; EBV-associated malignancies; autoimmune diseases; diagnostic and therapeutic
(This special issue belongs to the Section Human Virology and Viral Diseases)
Preparation for the Next Potential Pandemic—Chikungunya, Dengue, Zika and Other Viruses
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 7778 | Submission Open
Keywords: chikungunya; dengue; zika; next pandemic; epidemiology; pharmaceutics; immunology
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Biomarkers for Viral Infection submission deadline 31 Dec 2025 | 3 articles | Viewed by 5989 | Submission Open
Keywords: molecular biomarkers; viral infections
(This special issue belongs to the Section Animal Viruses)
Application of Genetically Engineered Plant Viruses
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 5422 | Submission Open
Keywords: plant virus; infectious clone; viral vector; virus-induced gene silencing (VIGS); virus-like particles (VLPs); cross-protection
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Interplay Between Influenza Virus and Host Factors
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4525 | Submission Open
Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications
(This special issue belongs to the Section Animal Viruses)
Intra-patient Viral Evolution and Diversity
edited by Adam A. Capoferri and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3863 | Submission Open
Keywords: intra-patient viral evolution; drug resistance; immune escape; co-evolution; virus persistence; virus evolution
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Virus–Insect Interactions, 2nd Edition
edited by Li-Long Pan
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3783 | Submission Open
Keywords: plant virus-insect vector interactions; virus transmission; entomopathogenic virus-insect host interactions; insect-specific viruses; induction and suppression of immune responses
(This special issue belongs to the Section Invertebrate Viruses)
Surveillance, Transmission Dynamics, and Control of Zoonotic Viruses
edited by Dimitrios A. Chatzidimitriou, and Ilias Bouzalas
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3439 | Submission Open
Keywords: zoonosis; surveillance; epidemiology; diagnostics
(This special issue belongs to the Section Animal Viruses)
Emerging Microbes, Infections and Spillovers, 2nd Edition submission deadline 31 Dec 2025 | 3 articles | Viewed by 2739 | Submission Open
Keywords: emerging infections; virus spillovers; microbes; cross-species transmission; virus evolution; viral disease; virus reservoirs; virus– host interaction; pathogenesis
(This special issue belongs to the Section Animal Viruses)
Lung Immunity to Viral Infections submission deadline 31 Dec 2025 | 1 articles | Viewed by 2467 | Submission Open
Keywords: respiratory virus; lung immune response; vaccines to respiratory virus; microbiota and lung immune response; environmental factors and lung immune responses; virus– host interaction in the lung; immunotherapies to prevent or treat respiratory viral infection
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Severe Fever with Thrombocytopenia Syndrome Virus 2025
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2435 | Submission Open
Keywords: SFTS; SFTSV; emerging viral infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Human Hepatitis Viruses and Their Animal Homologues
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2431 | Submission Open
Keywords: hepatitis viruses; animal virome; genetic diversity; genomic organization; ecology and evolution; molecular biology; molecular epidemiology; zoonotic potential
(This special issue belongs to the Section General Virology)
Advancing Hepatitis Elimination: HBV, HDV, and HCV
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 2419 | Submission Open
Keywords: hepatitis elimination; HBV; HCV; HDV
(This special issue belongs to the Section Human Virology and Viral Diseases)
SARS-CoV-2, COVID-19 Pathologies, Long COVID, and Anti-COVID Vaccines
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2347 | Submission Open
Keywords: SARS-CoV-2; COVID-19; long COVID; anti-COVID vaccines; spikeopathy; renin– angiotensin system
(This special issue belongs to the Section Coronaviruses)
Porcine Viruses 2025
edited by , and
submission deadline 31 Dec 2025 | 3 articles | Viewed by 2005 | Submission Open
Keywords: epidemiology; pathogenesis; immune evasion; virus evolution; vaccine
(This special issue belongs to the Section Animal Viruses)
Coronavirus Pathogenesis and Virus-Host Interaction
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1914 | Submission Open
Keywords: COVID-19; SARS-CoV-2; SARS-CoV-1; MERS-CoV; pathogenesis; virus– host interaction; virus entry; host factors; animal models; SARS-CoV-2 variants
(This special issue belongs to the Section General Virology)
Antiviral Development for Emerging and Re-Emerging Viruses
edited by and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1830 | Submission Open
Keywords: protein– protein interaction; viral– host interaction; viral replication; antiviral; human viruses; emerging infections
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Harnessing AI and Machine Learning for Antiviral Development
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1488 | Submission Open
Keywords: artificial intelligence; machine learning; antiviral therapies; personalized medicine; drug discovery; drug repurposing; drug resistance
(This special issue belongs to the Section General Virology)
Viral Strategies and Cellular Countermeasures That Regulate mRNA Access to the Translation Apparatus: 2nd Edition submission deadline 31 Dec 2025 | 1 articles | Viewed by 1225 | Submission Open
Keywords: virus– host interactions; IRES elements; RNA structure; translation initiation; translational control; innate immune response; RNA modification
(This special issue belongs to the Section General Virology)
Virology and Immunology of Gene Therapy 2025
edited by Weidong Xiao and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1107 | Submission Open
Keywords: gene therapy; viral vector; vaccine; immune responses; viruses; AAV; lentiviral vectors; neutralizing antibody
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Animal Virus Discovery and Genetic Diversity: 2nd Edition
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1035 | Submission Open
Keywords: animal virus; evolution; genetic; diversity; richness; emerging viruses; virome; metagenomics; ecology; cross-species transmission; zoonotic
(This special issue belongs to the Section Animal Viruses)
Zika Virus and Congenital Zika Syndrome, 2nd Edition
edited by Marcos Vinicius da Silva Pone and Sheila Moura Pone
submission deadline 31 Dec 2025 | 1 articles | Viewed by 920 | Submission Open
Keywords: viral infections; Zika virus; congenital Zika syndrome
(This special issue belongs to the Section Human Virology and Viral Diseases)
Current: Measles Outbreak, a Global Situation
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 877 | Submission Open
Keywords: measles; vaccination; surveillance; complications; outbreaks
(This special issue belongs to the Section Human Virology and Viral Diseases)
Arboviruses and Climate, 2nd Edition
edited by José Lourenço and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 875 | Submission Open
Keywords: arbovirus; climate; climate change; arthropods; vectors; epidemiology; evolution; ecology; public health
(This special issue belongs to the Section Invertebrate Viruses)
The Structure and Function of Flavivirus Genes and Proteins
edited by and Kay Choi
submission deadline 31 Dec 2025 | 1 articles | Viewed by 731 | Submission Open
Keywords: flavivirus; structural protein; non-structural protein; 5'UTR; 3'UTR
(This special issue belongs to the Section General Virology)
Virological and Immunological Factors Underlying HBV Functional Cure and HBV Reactivation
edited by
submission deadline 31 Dec 2025 | Viewed by 617 | Submission Open
Keywords: HBV persistence; HBV functional cure; cccDNA; immunology of HBV; HBV reactivation; immune-escape mutations
(This special issue belongs to the Section Human Virology and Viral Diseases)
Advancing Research of Anelloviruses, Second Edition submission deadline 31 Dec 2025 | Viewed by 389 | Submission Open
Keywords: TTV; TTMV; TTMDV; virome; viral species; immune system; orphan virus
(This special issue belongs to the Section Human Virology and Viral Diseases)
Virus Bioinformatics 2025
edited by and
submission deadline 31 Dec 2025 | Viewed by 371 | Submission Open
Keywords: virus bioinformatics; software; viral metagenomics and ecology; virus– host interactions; viral diversity and evolution; virus identification
(This special issue belongs to the Section General Virology)
Phage Display in Cancer Diagnosis and Screening
edited by
submission deadline 31 Dec 2025 | Viewed by 335 | Submission Open
Keywords: phage display; cancer; diagnosis; screening; prognosis and monitoring
(This special issue belongs to the Section Bacterial Viruses)
Virus Biosensing
edited by Guobin Mao
submission deadline 31 Dec 2025 | Viewed by 320 | Submission Open
Keywords: virus detection; molecular diagnosis; immunoassay; nucleic acid amplification; CRISPR-based detection; nucleic acid assembly; biosensor; point-of-care testing
(This special issue belongs to the Section General Virology)
RNA Viruses Replication and Innate Immunity
edited by
submission deadline 31 Dec 2025 | Viewed by 315 | Submission Open
Keywords: RNA virus replication and transcription; pathogen-associated molecular patterns; interferons; cytokines; signaling pathways
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Tackling Viral Resistance—Advances in Mechanisms, Detection, and Control
edited by and Claudia Palladino
submission deadline 31 Dec 2025 | Viewed by 265 | Submission Open
Keywords: viral resistance; antiviral therapies; drug resistance mechanisms; epidemiology; diagnostic advancements; clinical management
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Immunology in Transplant Patients submission deadline 31 Dec 2025 | Viewed by 228 | Submission Open
Keywords: viral infections; transplant patients; immunocompromised; immune response; host– pathogen interactions; immunotherapies; diagnostic approaches; preventive strategies
(This special issue belongs to the Section Human Virology and Viral Diseases)
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