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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Development of Novel Mucosal Vaccines: Advances in Technology and Delivery

edited by

Mohamed I. Husseiny El-Sayed

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2479 | Submission Open

Keywords: oral vaccines; nasal vaccines; live attenuated vaccines; DNA vaccines; mRNA vaccines; viral vectors vaccine; nanoparticle delivery system; adjuvants; gene-based vaccine; microencapsulation

(This special issue belongs to the Section Therapeutic Vaccines and Antibody Therapeutics)

Advances in Vaccine Adjuvants

edited by Devyani Joshi and Sanjeev Kumar

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1646 | Submission Open

Keywords: infectious diseases; cancer vaccines; mechanisms of adjuvants; novel adjuvants; delivery systems; particulate adjuvants; innate immune response; adaptive immune response

(This special issue belongs to the Section Vaccine Adjuvants)

Challenges to Developing New Vaccines and Improving Existing Platforms

edited by

S. Louise Cosby

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1482 | Submission Open

Keywords: infectious disease; cancer vaccines; humoral and cellular immunity; flaviviruses vaccines; inactivated and subunit vaccines; novel assays

Novel Immunotherapies, Cell Therapies and Cancer Vaccines

edited by

Vita Golubovskaya

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1167 | Submission Open

Keywords: cell therapy; vaccine; cancer; immunotherapy; antibody

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Vaccination Against Major Respiratory Pathogens in Livestock Farming

edited by

Enrico Brugnera

submission deadline 31 Jan 2026 | 1 articles | Viewed by 729 | Submission Open

Keywords: respiratory tract infections; innate and adaptive immune responses; vaccines; safety issues; risks and benefits studies

(This special issue belongs to the Section Veterinary Vaccines)

Immune Responses After Malaria Infection and Next Generation Malaria Vaccine

edited by Yu-Min Chuang

submission deadline 31 Jan 2026 | Viewed by 349 | Submission Open

Keywords: humoral immune response; cellular immune response; malaria; antimalaria vaccine; Plasmodium

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for Porcine Diseases

edited by Xiaohu Wang and

Lizette M. Cortes

submission deadline 31 Jan 2026 | Viewed by 278 | Submission Open

Keywords: vaccine development; immune mechanisms; adjuvants; global animal health; porcine diseases; vaccine candidate targets

(This special issue belongs to the Section Veterinary Vaccines)

Reactive Vaccination During Outbreaks

edited by Giuseppe Ippolito, Gary Kobinger and Giovanni Rezza

submission deadline 31 Jan 2026 | Viewed by 226 | Submission Open

Keywords: vaccination strategies; reactive vaccination; vaccine efficacy; efficiency; duration of protection; and the selection of populations

(This special issue belongs to the Section Human Vaccines and Public Health)

Chronic Viral Infections and Cancer: Openings for Vaccines and Cure

edited by

Maria G. Isaguliants

and Karl Ljungberg

submission deadline 31 Jan 2026 | Viewed by 220 | Submission Open

Keywords: chronic viral infection; oncogenic viruses; hepatitis B virus; high risk human papillomaviruses; hepatitis C virus; epstein– barr virus; human immunodeficiency virus type I; cancer associated with viral infection; immunotherapy; prophylactic viral vaccines; therapeutic viral vaccines

Host Immunity and Vaccines for Respiratory Pathogens

edited by

Hanqing He

and

Yuxia Liang

submission deadline 31 Jan 2026 | Viewed by 192 | Submission Open

Keywords: vaccines; immunity; infectious disease; respiratory pathogens

The Era of Vaccines: Advancing Tumor Immunology and Immunotherapy

edited by

Surendra Shukla

and

Vinay Kumar

submission deadline 31 Jan 2026 | Viewed by 131 | Submission Open

Keywords: cancer immunotherapy; tumor microenvironment; immune editing; immune checkpoints; CAR-T and NK therapy; biomarkers for immunotherapy

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Vaccine Design and Development

edited by

Vladimir Temchura

submission deadline 31 Jan 2026 | Viewed by 94 | Submission Open

Keywords: vaccine design; vaccine development; vaccinology; immunization; immune response; vaccine delivery; vaccine efficacy

(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)

Recent Research on Human Papillomavirus (HPV) Infection and Vaccination: 2nd Edition

edited by

Li Shi

and Yufeng Yao

submission deadline 31 Jan 2026 | Viewed by 84 | Submission Open

Keywords: HPV infection; HPV vaccination; willingness; hesitancy; therapeutic vaccines; cervical cancer prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Communicable Diseases: New and Old Therapies and Preventive Strategies, 2nd Edition

edited by

Cristina Genovese

Calimeri Sebastiano

, Daniela Lo Giudice,

Vincenza La Fauci

and

Vincenza Gianfredi

submission deadline 26 Feb 2026 | Viewed by 52 | Submission Open

Keywords: vaccines; therapies; communicable diseases

Improving HPV Vaccination Coverage: Current Issues, Future Prospects and Strategies

edited by

Irena Ilic

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7896 | Submission Open

Keywords: HPV vaccine; HPV-related cancers; vaccination; vaccine coverage; vaccine acceptance; vaccine hesitancy; vaccines knowledge; attitudes and practice; immunity; prevention

(This special issue belongs to the Section Human Papillomavirus Vaccines)

Viral Infections, Host Immunity and Vaccines

edited by Salman L. Butt and

Henry Kariithi

submission deadline 28 Feb 2026 | 6 articles | Viewed by 7567 | Submission Open

Keywords: multi-omics; innate immunity; spatial; virulence; persistence

(This special issue belongs to the Section Pathogens-host Immune Interface)

Recombinant Vaccine for Human and Animal Diseases

edited by

Shawn Babiuk

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5945 | Submission Open

Keywords: subunit vaccines; protein expression; synthetic biology; virus like particles; bacterial antigens; baculovirus antigens; plant antigens

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines to Reduce Antimicrobial Resistance to Bacterial Pathogens

edited by

Miriam Moscoso

, Astrid Pérez and Eva Gato

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3794 | Submission Open

Keywords: antimicrobial resistance; immune responses; infectious diseases; bacterial vaccines; antibody response; cellular response; mucosal immunity; efficacy evaluation; vaccine development

(This special issue belongs to the Section Pathogens-host Immune Interface)

Enterovirus Vaccines Development and Immune Responses Following Immunization

edited by

Yuefei Jin

and

Shuaiyin Chen

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3459 | Submission Open

Keywords: enterovirus; vaccine; immune efficacy; immune response

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Nanoparticle-Based Delivery Systems for Vaccines

edited by

Sergio Rosales-Mendoza

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1521 | Submission Open

Keywords: virus-like particle; nanocage; chimeric antigen; mucosal vaccine; nanoadjuvant; nanoparticle

(This special issue belongs to the Section Vaccine Adjuvants)

The Effectiveness of Influenza Vaccine

edited by Filippo Ansaldi and

Amicizia Daniela

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1354 | Submission Open

Keywords: effectiveness; influenza vaccines; infection control; influenza vaccination; seasonal influenza vaccines

(This special issue belongs to the Section Influenza Virus Vaccines)

Vaccine Strategies to Prevent Community-Acquired Pneumonia

edited by

Vissaria Sakka

and

Garyphallia Poulakou

submission deadline 28 Feb 2026 | Viewed by 517 | Submission Open

Keywords: community-acquired respiratory infections; Streptococcus pneumoniae; Staphylococcus aureus; influenza; pneumonia; respiratory infections; respiratory pathogens

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Safety and Side Effects in SARS-CoV-2 Vaccine

edited by

Ying-Fei Yang

and

Sher Singh

submission deadline 28 Feb 2026 | Viewed by 443 | Submission Open

Keywords: COVID-19 vaccine; vaccine adverse event reporting system (VAERS); vaccine safety datalink (VSD); adverse event; safety and side effects

(This special issue belongs to the Section Vaccine Efficacy and Safety)

Advances in DNA Vaccine Research

edited by Dabbu Jaijyan

submission deadline 28 Feb 2026 | Viewed by 297 | Submission Open

Keywords: DNA vaccines; DNA-vectored vaccine; vectors for DNA vaccines; adjuvants; DNA vaccine delivery

(This special issue belongs to the Section DNA and mRNA Vaccines)

Advancements in NK Vaccines for Solid Tumors: A Focus on Ongoing Clinical Trials

edited by

Yutao Wang

submission deadline 28 Feb 2026 | Viewed by 291 | Submission Open

Keywords: natural killer (NK) cell-based vaccines; solid tumors; cancer immunotherapy; clinical trials; immune response modulation

Mucosal Vaccines: Advances in Technology and Delivery

edited by

Kai Zhao

submission deadline 28 Feb 2026 | Viewed by 200 | Submission Open

Keywords: mucosal immunization; mucosal vaccine; adjuvant; vaccine delivery strategy; vaccine formulations; immune response

(This special issue belongs to the Section Vaccine Adjuvants)

Receptor-Binding Domain-Based Vaccines Against SARS-CoV-2

edited by Puthupparampil Scaria

submission deadline 28 Feb 2026 | 1 articles | Viewed by 137 | Submission Open

Keywords: RBD vaccine; COVID-19; vaccine; SARS-CoV-2

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Cancer Vaccines: Current Advances, Clinical Applications, and Future Directions

edited by

Paulina Niedźwiedzka-Rystwej

, Kajetan Kiełbowski and

Rafał Becht

submission deadline 28 Feb 2026 | Viewed by 131 | Submission Open

Keywords: cancer; cancer vaccines; tumor microenvironment; mRNA vaccines; DNA vaccines; neoantigen vaccines; translational medicine

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Memory T Cells in Vaccine-Induced Immunity for Infectious Diseases

edited by Bingdong Zhu

submission deadline 28 Feb 2026 | Viewed by 107 | Submission Open

Keywords: memory T cells; vaccination; adjuvant; immune strategy; infectious disease

Applications of Nanoparticles in Vaccines

edited by Kirsty Wilson,

Magdalena Plebanski

and Nhiem L. Tran

submission deadline 28 Feb 2026 | Viewed by 93 | Submission Open

Keywords: nanoparticles; vaccine design; nanoparticle applications in vaccines; antigen incorporation with nanoparticles; physicochemical properties of nanoparticles; adjuvant properties of nanoparticles; mechanisms of nanovaccines; immune response; disease models

SARS-CoV-2: Infections, Treatment, and Development of Vaccines—2nd Edition

edited by

Yasunari Matsuzaka

and

Ryu Yashiro

submission deadline 28 Feb 2026 | Viewed by 82 | Submission Open

Keywords: SARS-CoV-2; vaccines; COVID-19; diagnosis; treatment; antibodies; monoclonal antibodies; recombinant protein

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Vaccination and Infectious Disease Epidemics

edited by

King-Pui Florence Chan

and

Ken Ka Pang Chan

submission deadline 28 Feb 2026 | Viewed by 76 | Submission Open

Keywords: vaccination; infectious disease; epidemics; vaccination efficacy

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Recent Advances in Ruminant Vaccines

edited by

Petr Slama

submission deadline 28 Feb 2026 | Viewed by 56 | Submission Open

Keywords: mastitis; ruminant; vaccine; mammary gland; cattle; inflammation

Advances in Veterinary Vaccine Development and Immunoprophylaxis for Livestock Diseases

edited by

Viviana Parreno

and

Marina Bok

submission deadline 28 Feb 2026 | Viewed by 33 | Submission Open

Keywords: livestock vaccines; veterinary immunoprophylaxis; antibody-based vaccines; nanobodies; passive immunization strategies; One Health vaccinology; sustainable animal health

(This special issue belongs to the Section Veterinary Vaccines)

Advances in Vaccines against Infectious Diseases

edited by

Salvatore Giovanni De Simone

submission deadline 1 Mar 2026 | 16 articles | Viewed by 30036 | Submission Open

Keywords: vaccination; antigens; disease; immune; immunity; vaccine delivery; host responses; biodefence; emerging pathogens; MERS; parasites; virus; bacteria; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

African Swine Fever Virus Immunotherapies and Vaccine Development

edited by

Tao Feng

and Xiaodong Qin

submission deadline 1 Mar 2026 | Viewed by 289 | Submission Open

Keywords: ASFV; vaccine development; pathogenesis; immune evasion; diagnostic tools and technologies

(This special issue belongs to the Section Veterinary Vaccines)

Advances in Cancer Immunotherapy and Vaccines Research: 2nd Edition

edited by

Takumi Kumai

submission deadline 20 Mar 2026 | 8 articles | Viewed by 11883 | Submission Open

Keywords: tumor vaccine; immune adjuvants; tumor immune environment; peptide vaccine; chemoradiotherapy; cytokines; suppressive immune cells; checkpoint inhibitors

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Advancements in Vaccine Research: Epidemiology, Immunogenicity, Effectiveness and Safety

edited by

Chloé Dimeglio

submission deadline 20 Mar 2026 | Viewed by 354 | Submission Open

Keywords: vaccine epidemiology; immune response; immunogenicity; vaccine effectiveness; safety; infectious diseases; public health; vaccine development; immunization strategies

(This special issue belongs to the Section Vaccine Efficacy and Safety)

Innovative Strategies to Boost the Immunogenicity of Cancer Vaccines

edited by Eric O'Neill and

Shisong Jiang

submission deadline 20 Mar 2026 | Viewed by 16 | Submission Open

Keywords: cancer vaccines; tumor antigens; tumor-associated antigens (TAAs); tumor-specific antigens (TSAs); subunit vaccines; peptide vaccines; mRNA vaccines; viral vector vaccines; adjuvants; antigen presentation; MHC class I and II upregulation; cancer immunotherapy; antibody– drug conjugates (ADCs); T cell engages; combination immunotherapy

Porcine Bacteria and Virus Vaccines

edited by Huixing Lin

submission deadline 25 Mar 2026 | Viewed by 23 | Submission Open

Keywords: Porcine; bacteria; virus; vaccine; diarrhea; dyspnea; adjuvant; attenuated vaccine; live vector vaccine; peptide vaccine

(This special issue belongs to the Section Veterinary Vaccines)

The Recent Development of Influenza Vaccine: 2nd Edition

edited by

Ramireddy Bommireddy

submission deadline 31 Mar 2026 | 7 articles | Viewed by 11030 | Submission Open

Keywords: influenza; older population; adjuvants; universal vaccine

(This special issue belongs to the Section Influenza Virus Vaccines)

Vaccines and Vaccine Preventable Diseases

edited by Elie Saade and Stefan Gravenstein

submission deadline 31 Mar 2026 | 6 articles | Viewed by 5443 | Submission Open

Keywords: vaccine-preventable diseases (VPDs); at-risk populations; older adults; nosocomial transmission; vaccine equity; immunization disparities; public health policy; social determinants of health; infection control; prophylactic and therapeutic vaccines

(This special issue belongs to the Section Human Vaccines and Public Health)

From Knowledge to Action: Advances in Herpes Zoster Vaccine and Vaccination

edited by Giulia Silvestrini and

Manuela Chiavarini

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1961 | Submission Open

Keywords: knowledge; attitudes; and practices regarding herpes zoster vaccination; vaccine hesitancy; vaccine uptake and inequality; efficacy; reactogenicity; and safety of herpes zoster vaccine; efficacy of different vaccines; the role of different type of herpes zoster vaccine in different target of population; active campaign

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Novel Adjuvants and Delivery Systems for Vaccines

edited by Christiane Chbib and

Mohammad N. Uddin

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1353 | Submission Open

Keywords: vaccines; drug development; adjuvants; nanoparticle

(This special issue belongs to the Section Vaccine Adjuvants)

Cancer Vaccines and Immunotherapies

edited by

Subbaya Subramanian

submission deadline 31 Mar 2026 | Viewed by 301 | Submission Open

Keywords: cancer vaccines; tumor immunology; immunotherapy; mRNA vaccines; neoantigen-based therapies

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

Cancer Vaccines: 4th Edition

edited by

So Young Yoo

submission deadline 31 Mar 2026 | Viewed by 221 | Submission Open

Keywords: cancer immunotherapy; therapeutic vaccine; tumor-associated antigens; neoantigens; adjuvant; tumor microenvironment; oncolytic viruses; immune checkpoint inhibitors

(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)

SARS-CoV-2 Infection and COVID-19 Vaccination: Exploring Pathogenesis, Immune Response and Immunopathogenic Complications

edited by

Ronaldo B. Martins

, Tamara Rodrigues and Flavio Protasio Veras

submission deadline 31 Mar 2026 | Viewed by 215 | Submission Open

Keywords: SARS-CoV-2; COVID-19; vaccine adverse events; myocarditis and thrombosis; multisystem inflammatory syndrome; long COVID-19; immune response and autoimmunity; post-vaccine complications; therapeutic strategies; vaccine safety

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Veterinary Antiparasitic Vaccines

edited by

Miriam Tendler

and Marília Sirianni dos Santos Almeida

submission deadline 31 Mar 2026 | Viewed by 178 | Submission Open

Keywords: anti-parasitic vaccines; veterinary vaccines; vaccine manufacturing platforms; helminths; One Health; zoonosis; Immunization Agenda 2030

(This special issue belongs to the Section Veterinary Vaccines)

The Role of Vaccination on Public Health and Epidemiology

edited by

Antonio Rosa de Sousa Neto

and Daniela Reis Joaquim Reis Joaquim de Freitas

submission deadline 31 Mar 2026 | Viewed by 176 | Submission Open

Keywords: vaccines; immunization; epidemiology; public health; vaccine-preventable diseases; pandemic preparedness; health equity

(This special issue belongs to the Section Human Vaccines and Public Health)

Influenza Virus Infections, Vaccines and Diagnosis

edited by

Roberta Antonia Diotti

, Isabel Pagani and Valeria Caputo

submission deadline 31 Mar 2026 | Viewed by 173 | Submission Open

Keywords: influenza; avian influenza; monoclonal antibodies; vaccine; therapy; infection

(This special issue belongs to the Section Influenza Virus Vaccines)

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