Special Issue "Advancement in Leishmaniasis Diagnosis and Therapeutics"

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Neglected and Emerging Tropical Diseases".

Deadline for manuscript submissions: 28 August 2022 | Viewed by 399

Special Issue Editors

Dr. Fernanda Nazaré Morgado
E-Mail Website
Guest Editor
Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil
Interests: visceral leishmaniasis; canine leishmaniasis; cutaneous leishmaniasis; diagnostic; immunopathology; animal leishmaniasis
Dr. Renato Porrozzi
E-Mail Website
Guest Editor
Instituto Oswaldo Cruz, Fundacão Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil
Interests: visceral leishmaniasis; canine leishmaniasis; cutaneous leishmaniasis; diagnostic; immunopathology; animal leishmaniasis
Dr. Fatima Conceição-Silva
E-Mail Website
Guest Editor
Instituto Oswaldo Cruz, Fundacão Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil
Interests: cutaneous and mucocutaneous leishmaniasis; immune response; immunopathology; skin infectious diseases
Dr. Maria Inês Fernandes Pimentel
E-Mail Website
Guest Editor
Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro 21040-360, Brazil
Interests: cutaneous leishmaniasis; visceral leishmaniasis; infectious dermatology

Special Issue Information

Dear Colleagues,

Leishmaniasis is a complex of diseases that annually affect thousands of people in the world. Leishmanias are mainly zoonoses, affecting wild and domestic animals. According to their clinical manifestation, they are classified as tegumentary (TL) and visceral (VL) forms. The TL can lead to irreversible and inaesthetic sequelae, whereas VL can be lethal if not promptly diagnosed and treated. Correct diagnosis and adequate treatment constitute two important pillars of the control measures that demand: a) provision of specific and sensitive diagnostic tools widely available in the endemic regions, for the identification of human and animal cases; b) adequate treatment and management of humans and animals, reducing morbidity and mortality and allowing the interruption of the parasite transmission cycle. Advances in treatment have been limited to a few available drugs.

For decades, pentavalent antimony and amphotericin B have been considered the drugs of choice for most of Leishmania species, despite all side effects, for both cutaneous and visceral leishmaniasis. Pentamidine is the first option for L. (V.) guyanensis. Miltefosine and local therapeutic approaches have also been successfully used for cutaneous leishmaniasis. Efficient drugs are needed for the treatment of canine visceral leishmaniasis that may not result in resistant parasites. In many regions, only microscopic parasitological diagnosis is available. Despite many described molecular tools, they are almost limited to reference centers. Rapid tests have great potential in both cutaneous and visceral leishmaniasis due to the ease of storage and handling. However, studies focused on the development or improvement of diagnostic tools and treatment methods are needed.

This Special Topic aims to publish original articles, reviews and mini reviews, case reports, and short communications that are related to testing new drugs, new treatment strategies, identification of target molecules with potential use in treatment, serological, molecular and parasitological diagnosis applicable to improve control of human and animal leishmaniasis.

Dr. Fernanda Nazaré Morgado
Dr. Renato Porrozzi
Dr. Fatima Conceição-Silva
Dr. Maria Inês Fernandes Pimentel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • serological diagnosis
  • molecular diagnosis
  • parasitological diagnosis
  • treatment
  • visceral leishmaniasis
  • cutaneous leishmaniasis
  • human leishmaniasis
  • animal leishmaniasis

Published Papers

This special issue is now open for submission.
Back to TopTop