Advances in Molecular Diagnosis in Neglected Tropical Diseases
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366).
Deadline for manuscript submissions: 30 April 2025 | Viewed by 820
Special Issue Editor
Special Issue Information
Dear Colleagues,
Neglected tropical diseases (NTDs) remain a major public health problem in tropical and subtropical regions, with 10% of the world’s population being infected. The management and control of NTDs have been hampered by the difficulty in deploying rapid, specific, and affordable diagnostic tools in low-resource settings. Point-of-care real-time PCR (POC-qPCR) and loop-mediated isothermal amplification (LAMP) have emerged as an alternative to PCR for molecular diagnostics of NTDs, allowing a more affordable approach. These assays have been developed for the diagnosis of various NTDs and diseases associated with sanitary emergencies. These assays have shown promising results when compared to traditional methods. However, to address the diagnostic needs for NTDs, context-specific solutions are required that consider the end-user needs, available resources, and treatment options. Integrating diagnostic solutions to address multiple diseases simultaneously can help reduce the global burden of NTDs. In summary, molecular diagnostic techniques show promise for improving the diagnosis of NTDs, further research and development are needed to overcome the current limitations and ensure their widespread implementation as cost-effective, sensitive, and specific POC tests in endemic regions. So, we encourage this publication type demonstrating novel assays using molecular methods in microbiology and parasitology in novel emergency conditions and NTD diseases.
Dr. Rita De Cássia Pontello Rampazzo
Guest Editor
Manuscript Submission Information
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Keywords
- tropical emergent/reemergent pathogens
- novel molecular diagnosis
- point of care
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