Zearalenone (ZEN) and Deoxynivalenol (DON) Mycotoxicosis

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Mycotoxins".

Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 9016

Special Issue Editor


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Guest Editor
Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13,10-718 Olsztyn, Poland
Interests: mycotoxins; detection; feed; mycotoxicosis; immunology; diagnostics; animal pathology

Special Issue Information

Dear Colleagues,

Mycotoxicosis is the name given to the group of illnesses and disorders in humans and animals resulting from toxic secondary metabolites (mycotoxins) produced by some fungi species. Mycotoxicoses are acute and chronic toxic diseases. Their clinical features, target organs, and outcome depend on the intrinsic toxic features of the mycotoxin and the quantity and length of exposure, as well as the health status of the exposed animals. The most prevalent mycotoxins are produced by Fusarium which can produce mycotoxicosis, i.e., zearalenone (ZEN) and deoxynivalenol (DON). DON is known to elicit gastrointestinal disorders and immune suppression, whereas zearalenone creates estrogenic disturbances and shifts the immune response. For this reason, the Special Issue of Toxins will focus on the responses of different bodily systems in animals to various doses of DON or/and ZEN causing mycotoxicosis. We look forward to receiving your contributions for this Special Issue, in the form of original research, case studies, or review papers, shedding new light on DON and ZEN implications for disease developments in animals under realistic conditions.

Prof. Dr. Kazimierz Obremski
Guest Editor

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Keywords

  • deoxynivalenol
  • zearalenone
  • toxic effects
  • mycotoxicosis
  • gastrointestinal tract
  • reproductive system
  • immunomodulation

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Published Papers (1 paper)

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Review

24 pages, 898 KiB  
Review
Occurrence, Impact on Agriculture, Human Health, and Management Strategies of Zearalenone in Food and Feed: A Review
by Dipendra Kumar Mahato, Sheetal Devi, Shikha Pandhi, Bharti Sharma, Kamlesh Kumar Maurya, Sadhna Mishra, Kajal Dhawan, Raman Selvakumar, Madhu Kamle, Awdhesh Kumar Mishra and Pradeep Kumar
Toxins 2021, 13(2), 92; https://doi.org/10.3390/toxins13020092 - 26 Jan 2021
Cited by 125 | Viewed by 8216
Abstract
Mycotoxins represent an assorted range of secondary fungal metabolites that extensively occur in numerous food and feed ingredients at any stage during pre- and post-harvest conditions. Zearalenone (ZEN), a mycotoxin categorized as a xenoestrogen poses structural similarity with natural estrogens that enables its [...] Read more.
Mycotoxins represent an assorted range of secondary fungal metabolites that extensively occur in numerous food and feed ingredients at any stage during pre- and post-harvest conditions. Zearalenone (ZEN), a mycotoxin categorized as a xenoestrogen poses structural similarity with natural estrogens that enables its binding to the estrogen receptors leading to hormonal misbalance and numerous reproductive diseases. ZEN is mainly found in crops belonging to temperate regions, primarily in maize and other cereal crops that form an important part of various food and feed. Because of the significant adverse effects of ZEN on both human and animal, there is an alarming need for effective detection, mitigation, and management strategies to assure food and feed safety and security. The present review tends to provide an updated overview of the different sources, occurrence and biosynthetic mechanisms of ZEN in various food and feed. It also provides insight to its harmful effects on human health and agriculture along with its effective detection, management, and control strategies. Full article
(This article belongs to the Special Issue Zearalenone (ZEN) and Deoxynivalenol (DON) Mycotoxicosis)
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