Special Issue "Application of LC-MS/MS in the Mycotoxins Studies"
Deadline for manuscript submissions: closed (31 December 2019).
Interests: Development of analytical methods based on separative techniques, as LC-MS/MS, for determination of food contaminants, focusing on mycotoxins
Special Issues and Collections in MDPI journals
Interests: Targeted and untargeted analytical approaches based on High Resolution Mass Spectrometry for determination of known and unknown fungal secondary metabolites
Mycotoxins are secondary metabolites produced by fungi of different species, mainly Aspergillus, Fusarium or Penicillium, that can contaminate food and feed with toxic effects for humans and animals. Notifications on the Rapid Alert System for Food and Feed (RASFF) concerning mycotoxins are becoming frequent, being among the “top 10” hazards reported on food products, mainly cereals and nuts. Regulations around the world have established maximum levels for different mycotoxins in foodstuffs, including aflatoxins B1, B2, G1, G2 and M1, ochratoxin A, patulin, deoxynivalenol, zearalenone, fumonisins B1 and B2, HT-2 and T-2 toxins, citrinin, and ergot alkaloids. However, there are other “emerging mycotoxins” that have been considered as relevant as they could contribute to the risk posed to humans and animals. This group includes Alternaria toxins, sterigmatocystin, Fusarium toxins (as enniantins and beauvericin), phomopsins and others. Moreover, the so-called “modified mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing in mammals) can be more or less toxics than the original mycotoxin, and should also be taken into account.
All these facts make necessary the development of analytical methods for the accurate determination of mycotoxins in different food matrices and feeds. In this sense, liquid chromatography tandem mass spectrometry (LC-MS/MS) is a powerful tool for the unique identification and quantification of analytes, being the technique of choice when a multimycotoxin determination is required. Moreover, the use of high resolution mass spectrometry (HRMS) has allowed the identification of novel mycotoxins and a targeted / untargeted approaches for their study, including metabolomics.
This issue is dedicated to recent applications of LC-MS/MS in mycotoxin studies, including development of new analytical methods for their extraction in different matrices, identification and quantification, occurrence studies and metabolomics, or review articles about this topic.
Prof. Dr. Laura Gámiz-Gracia
Prof. Dr. Ana M. García-Campaña
Prof. Dr. Natalia Arroyo-Manzanares
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Emerging mycotoxins
- Modified mycotoxins
- Liquid chromatography
- Mass spectrometry