Special Issue "Current Knowledge on Bacterial Genotoxins and Their Effects on Host Cells"

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".

Deadline for manuscript submissions: 15 November 2019.

Special Issue Editor

Guest Editor
Dr. Gladys Mirey Website E-Mail
Toxalim INRA, 180 chemin de Tournefeuille, 31027 Toulouse, France

Special Issue Information

Dear Colleagues,

Bacterial genotoxins, inducing damage to DNA, are found in different bacterial species. Bacterial genotoxin archetypes are the cytolethal distending toxins (CDTs), holotoxins expressed in many gram-negative bacteria, and colibactin, a secondary metabolite produced through a complex biosynthetic chain by E. coli and other Enterobacteriaceae species.

However, few genotoxins are currently known, and general concerns regarding their mode-of-action and host-cell effects are growing. Indeed, due to their common characteristic of being able to damage DNA, genotoxins may lead to plethora of cell–host responses, from cell-cycle checkpoints to cell death, also including senescence, inflammation, etc.

This Special Issue will focus on current knowledge regarding genotoxins. Particularly, their function in host cells and their implications in different pathologies will be emphasized in order to provide an overview and shed new light concerning these specific questions.

Dr. Gladys Mirey
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Genotoxins
  • DNA damage
  • Cell response
  • Cell death
  • Senescence
  • Inflammation
  • Pathology

Published Papers

This special issue is now open for submission.
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