Special Issue "Botulinum Toxin: The Role in Neuro-Rehabilitation"
Deadline for manuscript submissions: closed (30 April 2019)
Prof. Dr. Andrea Santamato
Physical Medicine and Rehabilitation Section, Riuniti Hospital, University of Foggia, Italy
Current best practice in neuro-rehabilitation aims to increase the residual motor upper and lower limb function impeded by the muscles hyperactivity or movement disorders reducing abnormal posture, pain and spastic dystonic movements, in order to increase a functional recovery through rehabilitation treatments.
Botulinum toxin represents the gold standard therapy not only for positive muscles symptoms (i.e. focal spasticity, focal dystonias, spasms or muscle painful contractures) related to stroke, brain and spinal cord injuries, but also for autonomic disorders (i.e., secretory, bladder), with many label and off-label indications.
Moreover, several researches have shown a double action of botulinum toxin, not only at motor endplates, but also at the central level after peripheral intervention.
There is increasing evidence that the best choice of dosage, as well as the selection of correct muscles, the time of re-injection and correct techniques depend on the clinicians’ experience, due to a lack of approved guides. However, it is important, before each botulinum toxin treatment, to have an adequate goal for the treatment considering a patient-centered approach.
The focus of this Special Issue of Toxins will be on botulinum toxin in neuro-rehabilitation. I invite you to submit original research articles and reviews about label and off label indications, as well as the different effects related to doses, injection techniques, outcome measures, sensorimotor changes, post injections treatments, cost-effectiveness analyses, both in adults and in children affected by central and peripheral nervous system lesions.
Prof. Dr. Andrea Santamato
Manuscript Submission Information
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- Botulinum toxin type A
- Injection techniques
- Brain and spinal cord injuries