Bacillus thuringiensis: A Broader View of Its Biocidal Activity v2.0

Dear Colleagues,

Bacillus thuringiensis (Bt), a Gram-positive entomopathogenic bacterium, stands as the standard of microbial insecticides, boasting diverse strains equipped with plasmids housing an array of insecticidal genes. Over time, Bt-derived products have become the most widely marketed microbial insecticides, leveraging their efficacy in combating a multitude of insect pests.

The repertoire of encoded pesticidal proteins extends to both crystal and vegetative insecticidal proteins, demonstrating high toxicity across a wide spectrum of invertebrates. These proteins have been incorporated into crops, thus endowing them with resistance against some of the most destructive insect species globally.

Despite initial success, the relentless exposure of targeted insects to Bt crops has led to the emergence of resistance to commonly used insecticidal proteins. This phenomenon has prompted global screening programs in search of Bt strains that harbor novel insecticidal proteins. The objective is not only to counteract insect resistance, but also to expand the host range, thus fortifying the effectiveness of Bt-based insecticides.

In line with these developments, we are thrilled to present the second version of our Special Issue, entitled “Bacillus thuringiensis: A Broader View of Its Biocidal Activity v2.0.” This edition will delve into the detailed characterization of isolated Bt strains and novel insecticidal proteins, unveiling their unique biocidal activities, structural information and mode of action. The focus extends beyond mere insect resistance management to encompass the augmentation of host spectrums, thereby paving the way for sustainable and comprehensive pest control strategies.

Dr. Leopoldo Palma
Dr. Diego Herman Sauka
Prof. Dr. Primitivo Caballero
Guest Editors

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• Bacillus thuringiensis
• pesticidal proteins
• crystal proteins
• vegetative insecticidal proteins
• invertebrate pests
• biological control
• crop protection