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Most Cited

  • Review
  • Open Access
47 Citations
12,376 Views
41 Pages

Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications

  • Deepak Kulkarni,
  • Dipak Gadade,
  • Nutan Chapaitkar,
  • Santosh Shelke,
  • Sanjay Pekamwar,
  • Rushikesh Aher,
  • Ankita Ahire,
  • Manjusha Avhale,
  • Rupali Badgule and
  • Radhika Bansode
  • + 1 author

Microneedles are gaining popularity as a new paradigm in the area of transdermal drug delivery for biomedical and healthcare applications. Efficient drug delivery with minimal invasion is the prime advantage of microneedles. The concept of the micron...

  • Review
  • Open Access
39 Citations
11,932 Views
34 Pages

Cancer is a large group of diseases that can affect any organ or body tissue due to the abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic agents are highly toxic with a low level of selectivity. Additionally, th...

  • Review
  • Open Access
35 Citations
11,256 Views
20 Pages

Chromobacterium Violaceum: A Model for Evaluating the Anti-Quorum Sensing Activities of Plant Substances

  • Petya D. Dimitrova,
  • Tsvetozara Damyanova and
  • Tsvetelina Paunova-Krasteva

In the new antibiotic era, the exponential increase in multiresistant bacterial strains has become the main global health problem. Many researchers have focused their efforts on exploring novel or combined strategies for combating bacterial resistanc...

  • Review
  • Open Access
31 Citations
23,707 Views
24 Pages

A Review of the Biological Properties of Purple Corn (Zea mays L.)

  • Hee Yeon Kim,
  • Ki Yeon Lee,
  • Minju Kim,
  • Minji Hong,
  • Ponnuvel Deepa and
  • Songmun Kim

In the food and beverage industries, replacing synthetic colorants with plant-based colorants has become popular in recent times. Purple corn (Zea mays L.) is an important source of natural colorants due to its range in color from orange to purple. T...

  • Review
  • Open Access
29 Citations
3,600 Views
28 Pages

Targeting c-MYC G-Quadruplexes for Cancer Treatment with Small Molecules

  • Prasanth Thumpati,
  • Sachchida Nand Rai,
  • Chandrabhan Prajapati,
  • Kakarla Ramakrishna and
  • Santosh Kumar Singh

Novel therapies are required due to the rising cancer burden. Conventional chemotherapeutics tend to be particularly toxic, but there is a promising alternative for oncogenes, such as c-MYC. Often overexpressed in many cancer types, the potential c-M...

  • Review
  • Open Access
27 Citations
8,030 Views
18 Pages

Antiviral Molecular Targets of Essential Oils against SARS-CoV-2: A Systematic Review

  • Muhammad Iqhrammullah,
  • Diva Rayyan Rizki,
  • Agnia Purnama,
  • Teuku Fais Duta,
  • Harapan Harapan,
  • Rinaldi Idroes and
  • Binawati Ginting

Essential oils are potential therapeutics for coronavirus disease 2019 (COVID-19), in which some of the volatile compounds of essential oils have been well known for their broad antiviral activities. These therapeutic candidates have been shown to re...

  • Review
  • Open Access
24 Citations
19,455 Views
16 Pages

Wide Use of Hyaluronic Acid in the Process of Wound Healing—A Rapid Review

  • Magdalena Antoszewska,
  • Ewa Maria Sokolewicz and
  • Wioletta Barańska-Rybak

Hyaluronic acid (HA), as one of the main components of the extracellular matrix (ECM), plays an important role in the process of wound-healing and tissue-repair processes due to its unique properties and different physiological functions. HA has an a...

  • Article
  • Open Access
21 Citations
4,819 Views
18 Pages

21 December 2022

To explore the performance of the cationic nanocarrier leciplex (LPX) in escalating the oral bioavailability of vancomycin hydrochloride (VAN) by promoting its intestinal permeability. With the aid of a D-optimal design, the effect of numerous factor...

  • Article
  • Open Access
20 Citations
5,253 Views
14 Pages

Antimicrobial Activity of Novel Deep Eutectic Solvents

  • Noor Akbar,
  • Naveed Ahmed Khan,
  • Taleb Ibrahim,
  • Mustafa Khamis,
  • Amir Sada Khan,
  • Ahmad M. Alharbi,
  • Hasan Alfahemi and
  • Ruqaiyyah Siddiqui

Herein, we utilized several deep eutectic solvents (DES) that were based on hydrogen donors and hydrogen acceptors for their antibacterial application. These DES were tested for their bactericidal activities against Gram-positive (Streptococcus pyoge...

  • Review
  • Open Access
17 Citations
17,515 Views
19 Pages

In Vitro and Ex Vivo Models for Screening Topical Anti-Inflammatory Drugs

  • Juan Luis Pérez-Salas,
  • Martha Rocío Moreno-Jiménez,
  • Nuria Elizabeth Rocha-Guzmán,
  • Rubén Francisco González-Laredo,
  • Luis Medina-Torres and
  • José Alberto Gallegos-Infante

Skin inflammation occurs as an immune response to various stimuli such as ultraviolet light, irritants, or any type of skin barrier injury. Finding safe and effective drugs to combat skin inflammation remains a research challenge. Ethical and legal c...

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Sci. Pharm. - ISSN 2218-0532