Proteomics Studies of Stem Cells
A special issue of Proteomes (ISSN 2227-7382).
Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 506
Special Issue Editor
2. Department of Histology and Embryology, Poznan University of Medical Sciences, 60-701 Poznan, Poland
3. Prestage Department of Poultry Sciences, North Carolina State University, Raleigh, NC 27695, USA
4. Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland
5. Department of Obstetrics and Gynaecology, University Hospital and Masaryk University, 601 77 Brno, Czech Republic
Interests: biology and biotechnology of stem cells; human and animal ovarian granulosa and cumulus oophorus cells; luminal epithelial endometrial cells; oviductal epithelial cells; HUVECs; Wharton’s jelly; human cytotrophoblast cells; dental pulp cells; gingival cells and human oral mucosa; human vascular endothelium; human cardiac stem cells (cardiomyoblasts)
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Special Issue Information
Dear Colleagues,
The 21st century is undoubtedly the time of the most intensive research on the topic of stem cells. Stem cells are commonly used in animal model studies (e.g., mouse, rat, rabbit, as well as dog, pig or goat), both those in the field of basic research and aiming to design new forms of targeted therapy. The basic animal model studies focus on the analysis of physiological and biochemical properties of stem cells, while clinical research searches for the best way of cell-based therapy administration, as well as their interaction with drugs and other cells and tissues of the organism. In vitro research continues to play an important role in the medicine, as preclinical and clinical trials are still associated with a high risk of post-treatment complications. Nevertheless, stem cell therapies are increasingly common in orthopedics and traumatology, plastic surgery, aesthetic medicine, and cosmetology.
Additionally, there have been some far more advanced studies on the biotechnology of stem cells in bird, fish (Danio rerio), or Caenorhabditis elegans embryos, as well as plants.
Despite increasing knowledge on the physiological properties of stem cells, a large number of genetic, molecular, and biochemical studies still needs to be conducted. The development of transcriptomic and proteomic techniques allows for complex discovery of stem cell properties. Proteomic analyses, from the simple Western blot to advanced methods of mass spectrometry, permit the discovery and detailed molecular identification of new protein markers, the structure and biochemical activity of which is key from the viewpoint of therapeutic properties of stem cells.
This Special Issue aims to present the results of studies concerning proteomic analyses in the field of human, animal and plant stem cell bioengineering.
Dr. Bartosz Kempisty
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Proteomes is an international peer-reviewed open access quarterly journal published by MDPI.
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Keywords
- human stem cells
- animal stem cells
- plant stem cells
- stem cells therapy
- protein signaling pathways
- proteome assays
- mass spectrometry
- amino acids composition of proteins
- protein structure and enzyme activity
- biochemical properties of proteins
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